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Apoptosis Apoptosis Inducer Bcl-2 Caspase c-Myc c-RET DAPK IAP MDM2 p53 PD-1/PD-L1 PERK PKD Survivin Thymidylate Synthase TNF-alpha
Autophagy Autophagy CXCR LRRK2 ULK
Cell Cycle APC Aurora Kinase Casein Kinase CDK Chk c-Myc CRISPR/Cas9 CRM1 DHFR DNA/RNA Synthesis DUB DYRK eIF G-quadruplex Haspin Kinase HSP IRE1 Kinesin LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PD-1/PD-L1 PERK PLK PPAR PTEN RAD51 Rho ROCK Wee1 BUB HSF p21 E1/E2/E3 Enzyme
Cytoskeleton Akt Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK Wnt β-catenin Selectin Arp2/3 Complex PKC
DNA Damage ATM/ATR DNA/RNA Synthesis DNA Alkylator/Crosslinker DNA-PK HDAC MTH1 PARP Sirtuin Telomerase Topoisomerase
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Epigenetics AMPK Aurora Kinase CECR2 DNA Methyltransferase Epigenetic Reader Domain HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK microRNA PAD PARP Pim PKC Sirtuin
GPCR/G Protein Adenosine Receptor Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRTH2 CXCR Dopamine Receptor Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor Guanylate Cyclase Hedgehog Histamine Receptor Imidazoline Receptor LPA Receptor LTR mGluR Motilin Receptor MT Receptor Neurotensin Receptor NK Receptor NMUR Opioid Receptor OX Receptor OXTR P2Y Receptor PAFR PAR PKA Prostaglandin Receptor Ras RGS SGLT Sigma Receptor SSTR TSH Receptor Urotensin Receptor Vasopressin Receptor HDR More >>
Immunology/Inflammation CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTR MALT1 NADPH Oxidase NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK STING Thrombopoietin Receptor TLR Calcineurin IL IRF3 MIF S100A9 TSPO cGAS Immunology & Inflammation Related LTA4H MYD88
JAK/STAT Signaling EGFR JAK Pim STAT
LIF/Stat3 LIF
MAPK/ERK Pathway ERK JNK KLF MEK MLK MNK p38 MAPK Raf RSK MAP4K4
Membrane Transporter/Ion Channel AMPAR BCRP CFTR Chloride Channel CRAC Channel CRM1 EAAT2 HCN Channel MAT MCT Na+/Ca2+ Exchanger NKCC P2X Receptor P-gp Potassium Channel Proton Pump Sodium Channel TRPV URAT1 VDAC GABA Receptor IBAT Oct SGLT AChR ATPase Calcium Channel EAAT1 GlyT1 Na+/K+ ATPase NBC NMDAR TRP Channel SLC PIEZO1
Metabolic Enzyme 15-PGDH ACC ACE Adenosine Deaminase Adenosine Kinase AhR ALDH Aldose Reductase Aminopeptidase ATP Citrate Lyase Carbonic Anhydrase Cathepsin CETP COMT CPA Decarboxylase Dehydrogenase DGAT DHFR Elastase Enolase FAAH FABP Factor Xa FAS Ferroptosis FXR Glucokinase GLUT1 GSNOR GST Hexokinase HIF HIV Integrase HMGCR HSP Hydroxylase IDH IDO Lipase Lipoxygenase LXR MAO Mineralocorticoid Receptor NAE NAMPT Neprilysin P450 PAI-1 More >>
Neuronal Signaling AChE Adenosine Kinase Adrenergic Receptor AMPAR Amyloid-β CaMK CGRP Receptor COMT COX DAT Dopamine Receptor FAAH GABA Receptor GlyT1 Histamine Receptor Imidazoline Receptor MAO mGluR MT Receptor NK Receptor NMDAR Opioid Receptor OX Receptor P2X Receptor P-gp Secretase SSRIs Substance P Choline Cholinesterase Enkephalinase Glucosylceramide Synthase RAGE 5-HT Receptor AChR PIEZO1
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN RSK FOXO PHLPP
Protease Caspase Cysteine Protease DPP4 Glutaminase HIV Protease MMP Proteasome Secretase Ser/Thr Protease NEP Aspartic Protease Tyrosinase
Protein Tyrosine Kinase/RTK Ack1 ALK Bcr-Abl BMX Kinase BTK c-FMS c-Kit c-Met/HGFR c-RET DDR1/DDR2 Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 HER2 IGF-1R Insulin Receptor ITK PDGFR PKA PTK Pyk2 Src Syk TAM Receptor Tie-2 Trk Receptor VEGFR BRK
TGF-beta/Smad TGF-beta Receptor Smad TGF-beta
Stem Cells/Wnt Casein Kinase ERK Gli GSK-3 Hedgehog JAK MST Notch PKA PORCN ROCK Secretase sFRP-1 Smo STAT Wnt YAP β-catenin BMI-1
Phosphatase
Ubiquitin APC DUB NAE p97 Proteasome E1/E2/E3 Enzyme
NF-kB HDAC IKK MALT1 NF-kB NOD1 Nrf2 PPAR RIP Kinase TAK1
Others Phosphatase SRPK ECE FANCJ Fer/FerT Fucosyltransferase Galectin-3 GBF1 GCase HPPD LAT1 MLKL MPO MTP MTTP NMD Nur77 PCSK9 PFKFB3 Phosphorylase PKG Platelet Protein Synthesis Rev-ErbA Serine Hydrolase SQS STK33 Sweetener Tgase Urease VDA Vitamin XOR Cancer Stem Cells CD73 CerK Chelating Agent ITPKA Legumain OxPhos Others
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Wnt

Wnt

Wnt

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Cat. No.	Product Name	CAS No.	Information
CSN20456	NCB-0846	1792999-26-8	NCB-0846 is an TNIK inhibitor with IC50 value of 21 nM
CSN23594	Methyl Vanillate	3943-74-6	Methyl vanillate has ability to increase bone mass and activate wnt-catenin pathway It can act as a potential lead anabolic agent for anti-osteoporosis drugs
CSN22542	LF3	664969-54-4	LF3 is an inhibitor of canonical wnt signaling pathway with IC50 of less than 2 M It can disrupt the interaction between -catenin and TCF4
CSN16086	KY 02111	1118807-13-8	KY02111 can inhibit Wnt signaling and promote differentiation of hPSCs to cardiomyocytes
CSN16481	IWP-2	686770-61-6	IWP-2 is an inhibitor of porcn-mediated Wnt palmitoylation and secretion with IC50 of 27 nM
CSN21406	iCRT-3	901751-47-1	iCRT3 can inhibit both Wnt and -catenin-responsive transcription
CSN16814	iCRT 14	677331-12-3	iCRT 14 is a potent inhibitor of -catenin-responsive transcription CRT IC50 403 nM in assays of Wnt pathway activity Thought to directly influence the interaction between -catenin and TCF4 Induces marked G0G1 cell cycle arrest in HCT-116 and HT29 cell lines
CSN22412	Gigantol	67884-30-4	Gigantol is a bibenzyl compound derived from several medicinal orchids Giganto shows promising therapeutic potential against cancer cells Gigantol is a novel inhibitor of the Wnt-catenin pathway
CSN17991	CCT251545	1661839-45-7	CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with IC50 value of 5 nM
CSN12291	BML-284	853220-52-7	BML-284 is a Wnt signaling activator with EC50 value of 07 M for inducing -catenin and TCF-dependent transcriptional activity
CSN22337	Adavivint	1467093-03-3	Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCFLEF-reporter assay in SW480 colon cancer cells.
CSN22870	JW 67	442644-28-2
CSN23011	NSC 668036	144678-63-7
CSN22741	Cardionogen 1	577696-37-8
CSN22864	IWP 4	686772-17-8

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