Unc-51-like Kinases | Autophagy| CSNpharm

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Apoptosis Apoptosis Inducer Bcl-2 Caspase c-Myc c-RET DAPK IAP MDM2 p53 PD-1/PD-L1 PERK PKD Survivin Thymidylate Synthase TNF-alpha
Autophagy Autophagy CXCR LRRK2 ULK
Cell Cycle APC Aurora Kinase Casein Kinase CDK Chk c-Myc CRISPR/Cas9 CRM1 DHFR DNA/RNA Synthesis DUB DYRK eIF G-quadruplex Haspin Kinase HSP IRE1 Kinesin LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PD-1/PD-L1 PERK PLK PPAR PTEN RAD51 Rho ROCK Wee1 BUB HSF p21 E1/E2/E3 Enzyme
Cytoskeleton Akt Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK PKC Wnt β-catenin Selectin Arp2/3 Complex
DNA Damage ATM/ATR DNA/RNA Synthesis DNA Alkylator/Crosslinker DNA-PK HDAC MTH1 PARP Sirtuin Telomerase Topoisomerase
Endocrinology/Hormones 5 alpha Reductase ACE Androgen Receptor Aromatase ERR Glucocorticoid Receptor GPCR Opioid Receptor Progesterone Receptor Renin TPO Thyroid Hormone Receptor
Epigenetics AMPK Aurora Kinase CECR2 DNA Methyltransferase Epigenetic Reader Domain HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK microRNA PAD PARP Pim PKC Sirtuin
GPCR/G Protein AChR Adenosine Receptor Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRTH2 CXCR Dopamine Receptor Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor Guanylate Cyclase Hedgehog Histamine Receptor Imidazoline Receptor LPA Receptor LTR mGluR Motilin Receptor MT Receptor Neurotensin Receptor NK Receptor NMUR Opioid Receptor OX Receptor OXTR P2Y Receptor PAFR PAR PKA Prostaglandin Receptor Ras RGS SGLT Sigma Receptor SSTR TSH Receptor Urotensin Receptor Vasopressin Receptor More >>
Immunology/Inflammation CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTR MALT1 NADPH Oxidase NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK STING Thrombopoietin Receptor TLR Calcineurin IL IRF3 MIF S100A9 TSPO cGAS Immunology & Inflammation Related LTA4H MYD88
JAK/STAT Signaling EGFR JAK Pim STAT
MAPK/ERK Pathway ERK JNK KLF MEK MLK MNK p38 MAPK Raf RSK MAP4K4
LIF/Stat3 LIF
Membrane Transporter/Ion Channel AChR AMPAR BCRP CFTR Chloride Channel CRAC Channel CRM1 EAAT2 HCN Channel MAT MCT Na+/Ca2+ Exchanger NKCC P2X Receptor P-gp Potassium Channel Proton Pump Sodium Channel TRPV URAT1 VDAC GABA Receptor IBAT Oct SGLT ATPase Calcium Channel EAAT1 GlyT1 Na+/K+ ATPase NBC NMDAR TRP Channel SLC
Metabolic Enzyme 15-PGDH ACC ACE Adenosine Deaminase Adenosine Kinase AhR ALDH Aldose Reductase Aminopeptidase ATP Citrate Lyase Carbonic Anhydrase Cathepsin CETP COMT CPA Decarboxylase Dehydrogenase DGAT DHFR Elastase Enolase FAAH FABP Factor Xa FAS Ferroptosis FXR Glucokinase GLUT1 GSNOR GST Hexokinase HIF HIV Integrase HMGCR HSP Hydroxylase IDH IDO Lipase Lipoxygenase LXR MAO Mineralocorticoid Receptor NAE NAMPT Neprilysin P450 PAI-1 More >>
Neuronal Signaling AChE AChR Adenosine Kinase Adrenergic Receptor AMPAR Amyloid-β CaMK CGRP Receptor COMT COX DAT Dopamine Receptor FAAH GABA Receptor GlyT1 Histamine Receptor Imidazoline Receptor MAO mGluR MT Receptor NK Receptor NMDAR Opioid Receptor OX Receptor P2X Receptor P-gp Secretase SSRIs Substance P Choline Cholinesterase Enkephalinase Glucosylceramide Synthase RAGE 5-HT Receptor
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN RSK FOXO PHLPP
Protease Caspase Cysteine Protease DPP4 Glutaminase HIV Protease MMP Proteasome Secretase Ser/Thr Protease NEP Aspartic Protease Tyrosinase
Protein Tyrosine Kinase/RTK Ack1 ALK Bcr-Abl BMX Kinase BTK c-FMS c-Kit c-Met/HGFR c-RET DDR1/DDR2 Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 HER2 IGF-1R Insulin Receptor ITK PDGFR PKA PTK Pyk2 Src Syk TAM Receptor Tie-2 Trk Receptor VEGFR BRK
Stem Cells/Wnt Casein Kinase ERK Gli GSK-3 Hedgehog JAK MST Notch PKA PORCN ROCK Secretase sFRP-1 Smo STAT Wnt YAP β-catenin BMI-1
TGF-beta/Smad TGF-beta Receptor Smad TGF-beta
Ubiquitin APC DUB NAE p97 Proteasome E1/E2/E3 Enzyme
Phosphatase
NF-kB HDAC IKK MALT1 NF-kB NOD1 Nrf2 PPAR RIP Kinase TAK1
Others Phosphatase SRPK ECE FANCJ Fucosyltransferase Galectin-3 GBF1 GCase HPPD LAT1 MLKL MPO MTP MTTP NMD Nur77 PCSK9 PFKFB3 Phosphorylase PKG Platelet Protein Synthesis Rev-ErbA Serine Hydrolase SQS STK33 Sweetener Tgase Urease VDA Vitamin XOR Cancer Stem Cells CD73 CerK Chelating Agent ITPKA Legumain OxPhos Others
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PROTAC E1/E2/E3 Enzyme Others

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Cat. No.	Product Name	CAS No.	Information
CSN16884	SBI-0206965	1884220-36-3	SBI-0206965 is a potent selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2
CSN19225	MRT68921·xHCl	N/A	MRT68921xhydrochloride is a potent and dual autophagy kinase ULK12 inhibitor with IC50 of 29 nM and 11 nM respectively
CSN18901	MRT68921 HCl	2070014-87-6	MRT68921 hydrochloride is a selective inhibitor of ULK1 and ULK2 with IC50 0f 29 nM and 11 nM
CSN21387	LYN-1604	2088939-99-3	LYN-1604 is a potent UNC-51-like kinase 1 ULK1 agonist with an EC50 of 1894 nM
CSN22251	LYN-1604 HCl	2216753-86-3	LYN-1604 HCl is an agonist of ULK1 with EC50 of 1894 nM

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