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TRP Channel

Cat. No. Product Name CAS No. Information
CSN17046 Zucapsaicin 25775-90-0 Zucapsaicin is a synthetic cis isomer of natural capsaicin that has therapeutic efficacy in pain accompanying osteoarthritis of the knee.
CSN22050 WS-12 68489-09-8 WS-12 is an agonist of TRPM8 with an EC50 of 39 nM.
CSN19515 Vanillyl Alcohol   498-00-0 Vanillyl alcohol is a free radical scavenger with anticonvulsive and bile secretion promoting effect. It can be extracted from the herbs of Gastrodia elata Bl..
CSN16412 SN 2 823218-99-1 SN 2 is a potent activator of TRPML3 ion channel with EC50 of 18013 M
CSN25460 9-Phenanthrol 484-17-3 Selective TRPM4 blocker (IC50 = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.
CSN18624 RN-1734   946387-07-1 RN-1734 is selective antagonist of the TRPV4 channel completely antagonizes 4PDD-mediated activation of TRPV4 with comparable low micromolar IC50 values for all three species hTRPV4 IC50 23 M mTRPV4 IC50 59 M rTRPV4 IC50 32 M
CSN16213 Nonivamide   2444-46-4 Nonivamide, an analog of capsaicin, is agonist of transient receptor potential vanilloid type 1 (TRPV1). It can be extracted from the fruits of Capsicum annuum L..
CSN19023 ML204 HCl 2070015-10-8 ML204 HCl is a potent, selective TRPC4 channel inhibitor with IC50 of 0.96 μM.
CSN16140 Icilin   36945-98-9 Icilin is an agonist of TRPM8 ion channel with EC50 of 036 M in HEK 293 cells
CSN25462 EIPA 1154-25-2 EIPA (L593754) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
CSN16141 BCTC 393514-24-4 BCTC is a potent and specific inhibitor of transient receptor potential cation channel subfamily M member 8 TRPM8 in prostate cancer PCa DU145 cells
CSN12433 6-Gingerol   23513-14-6 6-Gingerol is activator transient receptor potential vanilloid receptor TRPV1 and TRP ankyrin receptor TRPA1 with EC50 of 3.3 M and 10.4 M. Its a natural chemical found in the rhizomes of ginger (Z. officinale).
CSN23287 2-Aminoethyl diphenylborinate   524-95-8 2-Aminoethyl diphenylborinate is an antagonist of membrane permeable IP3 receptor and a blocker of broad TRP channels including TRPC5 and TRPM2
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