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TNF-alpha

TNF-alpha

Cat. No. Product Name CAS No. Information
CSN15856 VGX-1027   6501-72-0 VGX-1027 is an orally active immunomodulatory agent that primarily targets macrophages, it can inhibit TNF- secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 26 signaling pathway. VGX-1027 also reduces the secretion of pro-inflammatory cytokines IL1-, IL-10 and IFN-.
CSN12073 Thalidomide   50-35-1 Thalidomide targets to CRBN with IC50 of 85 nM It can inhibit biosynthesis of TNF- and has anti-angiogenic and immunosuppressive effects
CSN21166 R-7050 303997-35-5 R-7050 is an antagonist of tumor necrosis factor receptor TNFR that towards TNF
CSN13185 Pomalidomide   19171-19-8 Pomalidomide can inhibit LPS-induced TNF- release with IC50 of 13 nM in PBMCs.
CSN13185 Pomalidomide   19171-19-8 Pomalidomide can inhibit LPS-induced TNF- release with IC50 of 13 nM in PBMCs.
CSN22471 Nedocromil Sodium 69049-74-7 Nedocromil Sodium is a potent TNF- inhibitor with an IC50 value of 1.67 M for Blood eosinophils.
CSN11280 Lenalidomide     191732-72-6 Lenalidomide a analog of thalidomide is TNF- secretion inhibitor with IC50 of 13 nM
CSN11280 Lenalidomide   191732-72-6 Lenalidomide a analog of thalidomide is TNF- secretion inhibitor with IC50 of 13 nM
CSN10385 Geraniin 60976-49-0 Geraniin is a naturally occuring dehydroellagitannin found in geraniums which can mediates apoptosis.
CSN16027 Forsythoside B 81525-13-5 Forsythoside B is a natural product isolated and purified from the fruits of Forsythia suspensa which inhibits inflammatory response,and has antioxidant properties with potent neuroprotective effects with a favorable therapeutic time-window, reduce of cerebral ischemia and reperfusion injury degree, attenuating blood-brain barrier (BBB) breakdown, and can rescue cardiac function from I/R injury.
CSN17109 Butoconazole Nitrate   64872-77-1 Butoconazole nitrate is an anti-fungal agent and the IC50s of IL-2 TNF IFN and GM-CSF are 72 gmL 144 gmL 736 gmL and 76 gmL respectively
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