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Tie-2
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN16555 | Tie2 kinase inhibitor 1 | 948557-43-5 | Tie2 kinase inhibitor is an optimized compound of SB-203580 selective to Tie2 with IC50 of 025 M 200-fold more potent than p38 |
| CSN26565 | GW768505A free base | 501693-25-0 | GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1]。 |
| CSN15710 | Cabozantinib | 849217-68-1 | Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-134, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM11.3 nM6 nM, 14.3 nM and 7 nM, respectively. |
| CSN22221 | BAY-826 | 1448316-08-2 | BAY-826 is a selective and potent TIE-2 inhibitor with Kdof 16 nM respectively |
| CSN51566 | (S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid | 1020412-97-8 |
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