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Thymidylate Synthase
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN10505 | Trifluridine | 70-00-8 | Trifluorothymidine is a derivative of thymidine that can inhibit thymidylate synthase and lead to DNA damage and apoptosis. It could be used to treat colorectal cancer. |
| CSN11829 | Raltitrexed | 112887-68-0 | Raltitrexed is an inhibitor of thymidylate synthase with IC50 of 9 nM in L1210 cell. |
| CSN26506 | Nolatrexed dihydrochloride | 152946-68-4 | Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Hence, it does not warrant further study as a single agent for this disease. |
| CSN63119 | Thymectacin | 232925-18-7 |
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