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TAK1
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN21193 | Takinib | 1111556-37-6 | Takinib is a selective TAK1 inhibitor with IC50 of 9.5 nM, it can induce apoptosis in a TNF-α-dependent manner in rheumatoid arthritis (RA) and breast cancer models. |
| CSN13920 | NG25 | 1315355-93-1 | NG25, a TAK1 inhibitor, inhibiting the activation of IKK by TLR7 and TLR9 agonists and preventing the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. |
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