TAK1
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN21193 | Takinib | 1111556-37-6 | Takinib is a selective TAK1 inhibitor with IC50 of 9.5 nM, it can induce apoptosis in a TNF-α-dependent manner in rheumatoid arthritis (RA) and breast cancer models. |
CSN13920 | NG25 | 1315355-93-1 | NG25, a TAK1 inhibitor, inhibiting the activation of IKK by TLR7 and TLR9 agonists and preventing the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. |
CSN21923 | 5Z-7-Oxozeaenol | 253863-19-3 | 5Z-7-Oxozeaenol is a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively. |