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Syk
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN20624 | TAK-659 HCl | 1952251-28-3 | TAK-659 HCl is a selective inhibitor of spleen tyrosine kinase (Syk) with IC50 of 3.2 nM. |
| CSN20342 | SYK Inhibitor II | 227449-73-2 | SYK inhibitor II is an inhibitor of SYK |
| CSN19150 | RO9021 | 1446790-62-0 | RO9021 potently inhibits SYK kinase activity with an average IC50 of 5.6 nM and suppresses B-cell receptor signaling. |
| CSN17403 | R788 Disodium | 1025687-58-4 | R788 disodium, the disodium form of R788, is a Syk inhibitor with IC50 of 41 nM. |
| CSN16059 | Fostamatinib 2Na 6H2O | 914295-16-2 | R788 Disodium is a Syk inhibitor with IC50 of 41 nM. It is the prodrug of metabolite R406 with immunomodulatory activity. |
| CSN12668 | R406 | 841290-80-0 | R406 is an inhibitor of Syk with IC50 of 41 nM. |
| CSN16942 | R406 Benzenesulfonate | 841290-81-1 | R406 benzenesulfonate is a selective inhibitor of Syk with IC50 of 41 nM |
| CSN18340 | R112 | 575474-82-7 | R112, an ATP-competitive inhibitor, can inhibit Syk kinase with Ki of 96 nM. |
| CSN15717 | PRT062607 | 1370261-96-3 | PRT062607 is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM with 80-fold selectivity for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70. |
| CSN16941 | PRT062607 HCl | 1370261-97-4 | PRT062607 HCl is an inhibitor of SYK with IC50 of 1 nM. |
| CSN19209 | PRT060318 2HCl | N/A | PRT060318 2HCl is a selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment. |
| CSN20186 | PRT-060318 | 1194961-19-7 | PRT-060318 is an inhibitor of Syk with IC50 of 4 nM. It is used to treat heparin-induced thrombocytopenia (HIT). |
| CSN12330 | Piceatannol | 10083-24-6 | Piceatannol a natural stilbene is selective Syk inhibitor extracted from the rhizomes of Polygonum cuspidatum Sieb et Zucc |
| CSN23020 | OXSI 2 | 622387-85-3 | OXSI 2 is a potent Syk kinase inhibitor with IC50 of 14 nM, and also inhibits assembly of NLRP3 inflammasomes induced by Nigericin. |
| CSN16634 | GS-9973 | 1229208-44-9 | GS-9973 is a Syk inhibitor with IC50 value of 7.7 nM which is used for the treatment of autoimmune and oncology indications. |
| CSN15818 | Fostamatinib | 901119-35-5 | Fostamatinib, a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM. |
| CSN22810 | ER 27319 Maleate | 1204480-26-1 | ER 27319 Maleate is a selective inhibitor of Syk kinase. |
| CSN16532 | BAY 61-3606 2HCl | 648903-57-5 | BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki 7.5 nM). |
| CSN18411 | BAY 61-3606 | 732983-37-8 | BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki 7.5 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
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