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STING

STING

Cat. No. Product Name CAS No. Information
CSN24506 STING agonist-3 2138299-29-1 STING agonist-3 is a selective small-molecule STING agonist which has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
CSN16863 ML RR-S2 CDA 1638241-89-0 ML RR-S2 CDA is a highly active cyclic-di-nucleotide immune stimulators that activate DCs via the cytoplamtic receptor STING (Stimulator of Interferon Genes).
CSN19006 ML RR-S2 CDA Ammonium 1638750-96-5 ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles.
CSN23676 H-151 941987-60-6 H-151 is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro.
CSN18324 c-Di-AMP 54447-84-6 Cyclic-di-AMP is a second messenger molecule produced in bacteria but not in mammals and can induce a strong immune response in vitro and in vivo.
CSN27873 ChX710 2438721-44-7 ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels.
CSN18467 cGAMP 849214-04-6 cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity.
CSN23535 C-178 329198-87-0 C-178 is a STING inhibitor that can block palmitoylation PMA-induced clustering of STING
CSN22907 C-176   314054-00-7 C-176 is a STING inhibitor with anti-inflammatory effect. It blocks the palmitoylation of STING by covalently targeting the transmembrane cysteine residue 91.
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