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STING
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN23755 | STING ligand-1 | 2365039-41-2 | STING ligand-1 is a lead STING ligand with IC50 of 68 nM for HAQ STING |
| CSN24506 | STING agonist-3 | 2138299-29-1 | STING agonist-3 is a selective small-molecule STING agonist which has durable anti-tumor effect and tremendous potential to improve treatment of cancer. |
| CSN18399 | STING agonist-1 | 702662-50-8 | STING agonist-1 is a human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. |
| CSN27270 | SR-717 | 2375421-09-1 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity . |
| CSN29565 | SN-011 | 2249435-90-1 | SN-011 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. SN-011 is a demethyl analogue of DUN99845. |
| CSN16863 | ADU-S100 | 1638241-89-0 | ML RR-S2 CDA is a highly active cyclic-di-nucleotide immune stimulators that activate DCs via the cytoplamtic receptor STING (Stimulator of Interferon Genes). |
| CSN19006 | ADU-S100 ammonium salt | 1638750-96-5 | ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles. |
| CSN23676 | H-151 | 941987-60-6 | H-151 is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro. |
| CSN29564 | SN-001 | 727699-84-5 | DUN99845 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. |
| CSN24296 | diABZI STING agonist-1 trihydrochloride | 2138299-34-8 | diABZI STING agonist-1 is a selective STING receptor agonist with EC50 value of 130nM. |
| CSN23276 | diABZI STING agonist-1 (Tautomerism) | 2138498-18-5 | diABZI STING agonist-1 is a selective stimulator of interferon genes STING receptor agonist with EC50s of 130 186 nM for human and mouse respectively |
| CSN18324 | c-di-AMP | 54447-84-6 | Cyclic-di-AMP is a second messenger molecule produced in bacteria but not in mammals and can induce a strong immune response in vitro and in vivo. |
| CSN27873 | ChX710 | 2438721-44-7 | ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels. |
| CSN18467 | cGAMP | 849214-04-6 | cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity. |
| CSN23535 | C-178 | 329198-87-0 | C-178 is a STING inhibitor that can block palmitoylation PMA-induced clustering of STING |
| CSN22907 | C-176 | 314054-00-7 | C-176 is a STING inhibitor with anti-inflammatory effect. It blocks the palmitoylation of STING by covalently targeting the transmembrane cysteine residue 91. |
| CSN26922 | 2',3'-cGAMP | 1441190-66-4 | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1]. |
| CSN38578 | cGAMP disodium | 2407516-83-8 | |
| CSN34985 | STING agonist-4 | 2138300-40-8 | |
| CSN42704 | diABZI STING agonist-1 | 2138299-33-7 | |
| CSN43448 | CL656 | 1951464-79-1 | |
| CSN60003 | SR-717 free acid | 2375420-34-9 | |
| CSN50645 | STING agonist-4 TFA | 2138300-41-9 | |
| CSN50642 | STING agonist-20 | 2591300-72-8 | |
| CSN50646 | E7766 diammonium salt | 2242635-03-4 | |
| CSN50643 | Oxoacridinylacetic acid derivatived STING agonist | 2332803-59-3 | |
| CSN50641 | diABZI STING agonist 4 | 2591300-74-0 | |
| CSN50648 | BNBC | 55171-63-6 | |
| CSN50647 | STING Agonist C11 | 875863-22-2 | |
| CSN62640 | STING-IN-2 | 346691-38-1 | |
| CSN67865 | STING-IN-3 | 2244881-69-2 | |
| CSN74760 | 4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide | 2247732-89-2 | |
| CSN85029 | STING agonist-12 | 2259624-71-8 | |
| CSN85113 | STING agonist-10 | 2259308-69-3 | |
| CSN85217 | STING agonist-11 | 2259308-68-2 | |
| CSN86641 | STING agonist-16 | 652142-94-4 | |
| CSN91562 | BSP16 | 2727249-47-8 |
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