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Steroids

Steroids

Cat. No. Product Name CAS No. Information
CSN21869 Triamcinolone Hexacetonide 5611-51-8 Triamcinolone hexacetonide is a commonly used long-acting steroids in treatment of subacute and chronic inflammatory joint diseases.
CSN16341 Timosaponin A3 41059-79-4 Timosaponin A3, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge, triggers liver injury through inducing ROS generation and suppressing the expression of BA transporters.
CSN16895 Tigogenin 77-60-1 Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway.
CSN14486 Thevetin B 27127-79-3 Thevetin B is a natural cardiac glycoside isolated and purified from the herbs of thevetia peruviana, is a Na-, K-dependent adenosinetriphosphatase (Na,K-ATPase) (EC 3.6.1.3) inhibitors.
CSN14078 Stigmasterol Glucoside 19716-26-8 Stigmasterol glucoside, a natural product isolated and purified from the herbs of Perilla frutescens (L.) Britt., may be a plant anticancer agent.
CSN13269 Stigmastane-3,6-Dione 22149-69-5 Stigmastane-3,6-dione is a natural product isolated and purified from the roots of Piper nigrum with anti-inflammatory activity and antifeedant activity against bell weevils.
CSN13265 Stigmastane-3,5,6-Triol 20835-91-0 Stigmastane-3,5,6-triol is a natural product isolated and purified from the fruits of Evodia rutaecarpa, which can be used for preparing antiviral medicine.
CSN13329 Stigmasta-5,8-Dien-3-Ol 570-72-9 Stigmasta-5,8-dien-3-ol is a natural product isolated and purified from the herbs of Stephania delavayi.
CSN13394 Stigmasta-4,25-Dien-3-One 848669-08-9 Stigmasta-4,25-dien-3-one is a natural product isolated and purified from the herbs of Porcelia macrocarpa.
CSN13326 Stigmasta-4,22-Dien-3-One 55722-32-2 Stigmasta-4,22-dien-3-one is a natural product isolated and purified from the flower of Magnolia biondii with anti-oxidant activity.
CSN13395 Stigmasta-4,22,25-Trien-3-One 848669-09-0 Stigmasta-4,22,25-trien-3-one is a natural product isolated and purified from the herbs of Callicarpa giraldiana.
CSN13331 Stigmast-4-Ene-3,6-Dione 23670-94-2 Stigmast-4-ene-3,6-dione is a natural product isolated and purified from the roots of Echium vulgare L. with anti-inflammatory and anti-allergic properties.
CSN13210 Stigmast-4-Ene-3,6-Diol 113626-76-9 Stigmast-4-ene-3,6-diol is a natural product isolated and purified from the barks of Ailanthus altissima.
CSN19882 Spicatoside B 87425-34-1 Spicatoside B is a natural product isolated and purified from Mentha spicata L.
CSN14032 Sitoindoside I 18749-71-8 Sitoindoside I is a natural product isolated and purified from the herbs of Woodwardia orientalis. with anti-ulcerogenic activity.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN19963 Ruscogenin 472-11-7 Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway.
CSN14080 Pseudoprotodioscin 102115-79-7 Pseudoprotodioscin shows a weaker suppressing effect on the production of inflammatory cytokines and can suppress melanogenesis in B16F1 cells. Its a natural product isolated and purified from the rhizomes of Dioscorea nipponica Makino. with moderate cytotoxicity.
CSN13540 Ophiopogonin A 11054-24-3 Ophiopogonin A is a natural product isolated and purified from the root of Liriope muscari (Decne.) Baily.
CSN11601 Oleandrin 465-16-7 Oleandrin, a natural product isolated and purified from the herbs of Nerium oleander L., inhibits the activity of NF-B in various cultured cell lines (U937, CaOV3, human epithelial cells and T cells) as well as it induces programmed cell death in PC3 cell line culture.
CSN14483 Odoroside H 18810-25-8 Odoroside H is a natural product isolated and purified from the herbs of Nerium indicum with anticancer activities. Its cytotoxic effects are induced by the inhibition of the plasma membrane bound Na()K()-ATPase.
CSN14711 Neritaloside 465-13-4 Neritaloside, a natural product isolated and purified from the herbs of Nerium indicum Mill., exhibits central nervous system depressant activity in mice at a dose of 25 mgkg.
CSN19362 Hecogenin 467-55-0 Hecogenin is a natural product isolated and purified from the roots of Aconitum carmichaeli Debx with antioxidant and anti-inflammatory properties, which can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway.
CSN13978 Gracillin 19083-00-2 Gracillin is a kind of steroidal saponin isolated and purified from the roots of Dioscorea opposita Thunb. and the root bark of wild yam Dioscorea nipponica with antitumor agent.
CSN19436 Gamabufotalin 465-11-2 Gamabufotalin, a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect.
CSN14033 Ergosta-7,22-Dien-3-One 32507-77-0 Ergosta-7,22-dien-3-one is a natural product isolated and purified from Lasiosphaera fenzlii with cytotoxic and antiinflammatory effect.
CSN13257 Ergosta-4,6,8(14),22-Tetraen-3-One 19254-69-4 Ergosta-4,6,8(14),22-tetraen-3-one, a natural product isolated and purified from the fruit body of Polyporus umbellatus preventing early renal injury in aristolochic acid-induced nephropathy rats and inducing G2M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
CSN14480 Ecdysterone 20,22-Monoacetonide 22798-96-5 Ecdysterone 20,22-monoacetonide is a natural product isolated and purified from the roots of Cyanotis arachnoidea C. B. Clarke.
CSN12576 Diosgenin   512-04-9 Diosgenin, a natural product isolated and purified from the rhizomes of Dioscorea zingiberensis C.H.Wright, is an important natural source of steroidal hormones, and has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
CSN12145 Diosgenin Glucoside 14144-06-0 Diosgenin glucoside is a natural product isolated and purified from the roots of Trillium tschonoskii Maxim., which may be of use in the management of hypercholesterolemia and atherosclerosis.
CSN19485 Dioscin   19057-60-4 Dioscin, a natural product isolated and purified from the rhizome of Dioscorea Zingiberensis C.H.Wright, is a potent ITGA5 inhibitor, showing potent anti-cancer effect against a variety of tumor cell lines.
CSN10769 Deoxycholic Acid   83-44-3 Deoxycholic Acid is a proinflammatory agent and used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.
CSN14482 Clerosterol Glucoside 123621-00-1 Clerosterol glucoside is a natural product isolated and purified from the fresh fruits of Momordica charantia L..
CSN19441 Cinobufagin 470-37-1 Cinobufagin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway, can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue, and act as a potent anticancer agent against MM and possibly exerts its effects through the ROS-mediated activation of ERK, JNK and p38 MAPK leading to the activation of caspase-3 in U266 cells.
CSN19995 Chonglou Saponin VII 68124-04-9 Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation.
CSN14077 Cerevisterol 516-37-0 Cerevisterol, a natural cytotoxic steroid isolated and purified from the fruit body of Ganoderma lucidum, can inhibit the activity of DNA polymerase alpha and stimulate NGF-mediated neurite outgrowth on PC12 cells.
CSN20257 Cepa2 N/A Cepa2 is a natural product isolated and purified from shallot (Allium cepa L. Aggregatum group) with anticancer activity.
CSN19435 Bufalin 465-21-4 Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro.
CSN18282 Arenobufagin 464-74-4 Arenobufagin is a natural bufadienolide from toad venom and has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2ADM cells.
CSN14485 Adynerin 35109-93-4 Adynerin is a natural product isolated and purified from the herbs of Nerium oleander.
CSN13299 6beta-Hydroxystigmast-4-En-3-One 36450-02-9 6beta-Hydroxystigmast-4-en-3-one is a natural product isolated and purified from the herbs of Phaseolus vulgaris showing potent cytotoxicity .
CSN15226 6-O-Methylcerevisterol 126060-09-1 6-O-Methylcerevisterol is a natural product isolated and purified from the fungus Ganoderma lucidum.
CSN13285 3,7,16-Trihydroxystigmast-5-Ene 289056-24-2 3,7,16-Trihydroxystigmast-5-ene is a natural product isolated and purified from the herbs of Walsura robusta.
CSN13271 3,5-Cycloergosta-6,8(14),22-Triene 24352-51-0 3,5-Cycloergosta-6,8(14),22-triene, (3,5S,22E)- is a natural product isolated and purified from Poria cocos(Schw.)Wolf..
CSN13400 3,5,9-Trihydroxyergosta-7,22-Dien-6-One 88191-14-4 3,5,9-Trihydroxyergosta-7,22-dien-6-one is a natural product isolated and purified from the fruit body of Ganoderma lucidum.
CSN20272 27-Hydroxycholesterol 20380-11-4 27-Hydroxycholesterol is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1.
CSN14478 22-Dehydroclerosteryl Acetate 28594-00-5 22-Dehydroclerosteryl acetate is a natural product isolated and purified from the leaves of Clerodendrum campbellii.
CSN14955 17alpha-Neriifolin 7044-31-7 17alpha-Neriifolin, a natural product isolated and purified from the herbs of Nerium indicum Mill., has little anti-proliferative activity, indicating that the 17beta configuration is critical for the anti-proliferative activity of these compounds.
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