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STAT

STAT

Cat. No. Product Name CAS No. Information
CSN20470 STX-0119 851095-32-4 STX-0119 is a potent STAT3 inhibitor STX-0119 is an efficient therapeutic to overcome TMZ resistance in recurrent GBM tumors and could be the next promising compound leading to survival prolongation
CSN10157 Stattic   19983-44-9 Stattic a nonpeptidic small molecule potently inhibits STAT3 activation and nuclear translocation with IC50 of 51 M in cell-free assays highly selectivity over STAT1
CSN20442 STAT5 Inhibitor 285986-31-4 STAT5 inhibitor suppresses STAT5 via interaction of its SH2 domain with IC50 of 47 M
CSN19288 Stafib-2 1688703-26-5 Stafib-2 selectively inhibits tyrosine phosphorylation of STAT5b in human leukaemia cells and induces apoptosis in a STAT5-dependent manner
CSN19226 STA-21 111540-00-2 STA-21 is a selective STAT3 inhibitor.
CSN22560 SH5-07 1456632-41-9 SH5-07 is an inhibitor of STAT3 with IC50 of 3906 M with antitumor effects and it can suppresse human glioma and breast cancer
CSN17881 SH-4-54 1456632-40-8 SH-4-54 is a potent small molecule nonphosphorylated STAT3 inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5 respectively
CSN15990 S3I-201 501919-59-1 S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 M and low activity towards STAT1 and STAT5
CSN11557 Nifuroxazide   965-52-6 Nifuroxazide suppresses the transcription activity of STAT1 STAT3 IC50 3 M in cells and STAT5 It is a nitrofuran-based antidiarrheal agent that can prevent urinary tract infections
CSN18451 Napabucasin 83280-65-3 Napabucasin is a first-in-class cancer stemness inhibitor that targets STAT3
CSN20515 inS3-54-A18 328998-53-4 inS3-54-A18 is an inhibitor of STAT3 that suppresses tumor growth metastasis and the expression of STAT3 target genes
CSN19012 HO-3867 1172133-28-6 HO-3867 selectively inhibits the phosphorylation and transcription of STAT3 It is an analog of curcumin
CSN16361 Cryptotanshinone   35825-57-1 Cryptotanshinone is a potent STAT3 inhibitor IC50 46 M and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells
CSN14607 Corylifol A 775351-88-7 Corylifol A is a phenolic compounds isolated from Psoralea corylifolia and inhibits IL-6-induced STAT3 activation and phosphorylation IC5008 M
CSN23522 Colivelin 867021-83-8 Colivelin is a peptide and activator of STAT3 with neuroprotective effects
CSN20212 C188-9 432001-19-9 C188-9 is a STAT3 inhibitor and has no effects on non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC) in mice.
CSN17200 BP-1-102 1334493-07-0 BP-1-102 is an orally available small-molecule inhibitor of transcription factor STAT3
CSN13598 AS-1517499 919486-40-1 AS-1517499 is a potent STAT6 inhibitor with IC50 of 21 nM.
CSN22827 Galiellalactone 133613-71-5
CSN22552 HJC0152 1420290-99-8
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