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SRPK

SRPK

Cat. No. Product Name CAS No. Information
CSN24738 ZT-12-037-01 2328073-61-4 ZT-12-037-01 is a STK19-targeted inhibitor with a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. It inhibited phosphorylation of NRAS (major isoform of Ras family) with IC50 value of 24nM.
CSN19078 WNK463 2012607-27-9 WNK463 is a potant With-No-Lysine WNK kinase inhibitor with IC50s of 5169 nM for WNK1234
CSN23673 SPHINX31 1818389-84-2 SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].
CSN17802 ML281   1404437-62-2 ML281 is a potent and selective serinethreonine kinase STK33 inhibitor with IC50 of 14 nM STK33 downregulation is toxic to KRAS-dependent cancer cell lines
CSN17687 MK2-IN-1 HCl   1314118-94-9 MK2-IN-1 HCl is a non-ATP competitive inhibitor of MAPKAPK2 (MK2) with IC50 of 0.11 μM.
CSN18951 ILK-IN-2 2070015-22-2 ILK-IN-2 is a ILK inhibitor
CSN12528 4μ8C   14003-96-4 48C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
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