Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN16616 | Praeruptorin B | 73069-28-0 | Praeruptorin D, a natural product isolated and purified from the roots of Peucedanum praeruptorum Dunn., can significantly inhibit the infiltration of activated polymorphonuclear leukocytes (PMNs) and decrease the levels of TNF-α and IL-6 in bronchoalveolar lavage fluid at the same dose, suppresses LPS induced Nuclear Factor-kappa B (NF-κB) pathway activation in the lung by decreasing the cytoplasmic loss of inhibitor κB-α (IκB-α) protein and inhibiting the translocation of p65 from cytoplasm to nucleus. |
CSN38450 | PF429242 dihydrochloride | 2248666-66-0 | PF429242 2HCl is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with IC50 value of 175nM. |
CSN13748 | Fatostatin hydrobromide | 298197-04-3 | Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
CSN19276 | Fatostatin | 125256-00-0 | Fatostatin A is an inhibitor of SREBP that directly binds SCAP and blocks its ER-to-Golgi transport with IC50 of 2.5 and 10 M in mammalian cells. |
CSN76150 | 4'-Hydroxyflavanone | 6515-37-3 |