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Src

Src

Cat. No. Product Name CAS No. Information
CSN16229 WH-4-023 837422-57-8 WH-4-023 is an inhibitor of Lck and Src with IC50 of 2 nM, 6 nM, respectively.
CSN17744 WEHI-345 Analog 1354825-62-9 WEHI-345 analog is a Src inhibitor
CSN13096 TG 100801 867331-82-6 TG 100801 is the prodrug of TG 100572 which is a multi-targeted kinase inhibitor that inhibit select growth factor receptor tyrosine kinases and Src family kinases with IC50 values of 272105 nM of VEGFR1VEGFR2FGFR1SrcFyn kianse respectively
CSN18504 TG 100572 867334-05-2 TG 100572 is a multi-targeted kinase inhibitor that inhibit select growth factor receptor tyrosine kinases and Src familt kinases with IC50 values of 272105 nM for VEGFR1VEGFR2FGFR1SrcFyn kianse respectively
CSN18503 TG 100572 HCl 867331-64-4 TG 100572 hydrochloride is a multi-targeted kinase inhibitor that inhibits select growth factor receptor tyrosine kinases and Src familt kinases with IC50 values of 27210.5 nM for VEGFR1VEGFR2FGFR1SrcFyn kianse respectively.
CSN17735 T338C Src-IN-2 1351927-00-8 T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM and also inhibits T338CV323A and T338CV323S with IC50 of 57 nM19 nM
CSN17734 T338C Src-IN-1 1351926-90-3 T338C Src-IN-1 is a potent mutant-Src T338C inhibitor and exhibits the most potent inhibition of T338C IC50111 nM relative to WT c-Src10-fold increase
CSN18218 SU6656 330161-87-0 SU 6656 is an inhibitor of Src kinases and can target Src Yes Lyn and Fyn with IC50 of 280 nM 20 nM 130 nM 170 nM respectively
CSN17355 Src Inhibitor 1   179248-59-0 Src inhibitor 1 is an inhibitor of Src and Lck with IC50 of 44 nM and 88nM
CSN12259 Saracatinib 379231-04-6 Saracatinib is Src inhibitor with IC50 of 27 nM
CSN23720 RK 24466   213743-31-8 RK-24466 is an inhibitor of Lck 64-509 and LckCD isoforms with IC50s of 2 nM
CSN11759 PP2   172889-27-9 PP2 is a ATP-competitive inhibitor of the Src family of protein tyrosine kinases. The IC50s for p56lck, p59fynT, Hck, Src are 4 nM, 5 nM, 5 nM, 100 nM, respectively.
CSN11758 PP1   172889-26-8 PP1 is a selective inhibitor of Src and LckFyn with IC50 of 5 nM, 6 nM, respectively.
CSN12857 PD173955 260415-63-2 PD173955 is an src family-selective tyrosine kinase inhibitor with IC50 of 22 nM for Src Yes and Abl kinase and is less potent for FGFR and no activity on InsR and PKC
CSN17507 MCB-613   1162656-22-5 MCB-613 is a stimulator of steroid receptor coactivator SRC
CSN16563 Lck Inhibitor 847950-09-8 Lck inhibitor is a class of compounds that are potent inhibitors of Lck with an IC50 value of 7 nM.
CSN18620 Lck Inhibitor 2 944795-06-6 Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively.
CSN18935 KX2-391 Mesylate 1080645-95-9 KX2-391 mesylate is an inhibitor of Src that targets the peptide substrate site of Src with GI50 of 9-60 nM in cancer cell lines
CSN16540 KX2-391 897016-82-9 KX2-391 is an inhibitor of Src with IC50 of 9 nM-60 nM in cancer cells It is the first clinical and peptidomimetic class Src inhibitor
CSN16378 KX2-391 2HCl 1038395-65-1 KX2-391 dihydrochloride is the first clinical Src inhibitor peptidomimetic class that targets the peptide substrate site of Src with GI50 of 9-60 nM in cancer cell lines
CSN13760 KX1-004 518058-84-9 KX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL
CSN19857 KB SRC 4 1380088-03-8 KB SRC 4 is a potent and selective c-Src inhibitor Ki 44 nM and does not inhibit c-Abl at concentrations up to 125 M
CSN11935 Bosutinib   380843-75-4 Bosutinib is an inhibitor of Src and Abl with IC50 of 12 nM and 1 nM
CSN18293 AZM475271 476159-98-5 AZM475271 is a potent and selective Src kinase inhibitor with IC50 of 5 nM showing no inhibitory activity on Flt3 KDR Tie-2
CSN17121 AMG-47a 882663-88-9 AMG-47a is a Lck inhibitor that can decrease T cell proliferation with anti-inflammatory activity.
CSN17856 A 419259 3HCl 1435934-25-0 A 419259 trihydrochloride is a broad-spectrum pyrrolo-pyrimidine inhibitor designed to enhance selectivity towards the Src family with IC50 of 9 nM 3 nM and 3 nM for Src Lck and Lyn respectively
CSN18243 A 419259 364042-47-7 A 419259 is an apoptosis inducing agent that inhibits Src family kinases c-Src and also induces apoptosis in CML cell ines and blocks Stat5 and Erk activation
CSN21118 7-Hydroxy-4-chromone 59887-89-7 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of 300 M
CSN13856 1-Naphthyl PP1 221243-82-9 1-Naphthyl PP1 is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl IC50 values are 10 06 06 18 and 22 M for v-Src c-Fyn c-Abl CDK2 and CAMK II respectively
CSN15753 1-Naphthyl PP1 HCl 956025-47-1 1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl IC50 values are 10 06 06 18 and 22 M for v-Src c-Fyn c-Abl CDK2 and CAMK II respectively
CSN23025 PD 166285 2HCl 212391-63-4
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