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Src
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN18218 | SU6656 | 330161-87-0 | SU 6656 is an inhibitor of Src kinases and can target Src Yes Lyn and Fyn with IC50 of 280 nM 20 nM 130 nM 170 nM respectively |
| CSN17355 | Src Inhibitor 1 | 179248-59-0 | Src inhibitor 1 is an inhibitor of Src and Lck with IC50 of 44 nM and 88nM |
| CSN23720 | RK 24466 | 213743-31-8 | RK-24466 is an inhibitor of Lck 64-509 and LckCD isoforms with IC50s of 2 nM |
| CSN11759 | PP2 | 172889-27-9 | PP2 is a ATP-competitive inhibitor of the Src family of protein tyrosine kinases. The IC50s for p56lck, p59fynT, Hck, Src are 4 nM, 5 nM, 5 nM, 100 nM, respectively. |
| CSN11758 | PP1 | 172889-26-8 | PP1 is a selective inhibitor of Src and LckFyn with IC50 of 5 nM, 6 nM, respectively. |
| CSN12857 | PD173955 | 260415-63-2 | PD173955 is an src family-selective tyrosine kinase inhibitor with IC50 of 22 nM for Src Yes and Abl kinase and is less potent for FGFR and no activity on InsR and PKC |
| CSN23025 | PD 166285 2HCl | 212391-63-4 | PD 166285 inhibited Src nonreceptor tyrosine kinase, fibroblast growth factor receptor-1, epidermal growth factor receptor and platelet-derived growth factor receptor beta subunit (PDGFR-beta), tyrosine kinases with half-maximal inhibitory potencies (IC50 values) of 8.4 +/- 2.3 nM (n = 6), 39.3 +/- 2.8 nM (n = 16), 87.5 +/- 13.7 nM (n = 6) and 98.3 +/- 7.9 nM (n = 16), respectively. |
| CSN12108 | MLR-1023 | 41964-07-2 | MLR-1023 is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals. |
| CSN18620 | Lck Inhibitor 2 | 944795-06-6 | Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively. |
| CSN11935 | Bosutinib | 380843-75-4 | Bosutinib is an inhibitor of Src and Abl with IC50 of 12 nM and 1 nM |
| CSN18243 | A 419259 | 364042-47-7 | A 419259 is an apoptosis inducing agent that inhibits Src family kinases c-Src and also induces apoptosis in CML cell ines and blocks Stat5 and Erk activation |
| CSN21118 | 7-Hydroxy-4-chromone | 59887-89-7 | 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of 300 M |
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