SOS1/KRAS (stapled peptide) refers the stapled peptide target the interaction between SOS1 and KRAS.
|Cat. No.||Product Name||CAS No.||Information|
|CSN27257||SAH-SOS1A||1652561-87-9||SAH-SOS1A is a KRAS-targeting stapled peptide with EC50 values of 106, 109, 154, 140, 155 and 175nM for K-Ras, K-Ras (G12D), K-Ras (G12V), K-Ras (G12C), K-Ras (G12S) and K-Ras (Q61H), respectively. It disrupts the SOS1/KRAS protein interaction and directly inhibit nucleotide association to wild-type and mutant KRAS proteins.|