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Sodium Channel

Sodium Channel

Cat. No. Product Name CAS No. Information
CSN24189 Rimeporide 187870-78-6 Rimeporide is a potent and selective NHE1 inhibitor.
CSN12584 Riluzole   1744-22-5 Riluzole is an antagonist of glutamate that used as an anticonvulsant. It can prolong the survival of patients with amyotrophic lateral sclerosis.
CSN18778 Proparacaine HCl   5875-06-9 Proparacaine HCl is an antagonist of voltage-gated sodium channels with ED50 of 3.4 mM.
CSN11774 Procaine   59-46-1 Procaine, a benzoic acid derivative, is an anesthetic drug through targeting multiple proteins.
CSN12795 Phenytoin 57-41-0 Phenytoin is an inactive voltage-gated sodium channel stabilizer.
CSN21395 PF-06869206 2227425-05-8 PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a SLC34A1 with an IC50 of 380 nM
CSN25458 Licarbazepine 29331-92-8 Licarbazepine, also known as BIA-2-005; GP-47779; LIC-477; LIC-477D; TRI-477, is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate. Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.
CSN12998 Lamotrigine   84057-84-1 Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition.
CSN20530 Eniporide 176644-21-6 Eniporide is an inhibitor of NaH exchange that prevents ischemic Na overload
CSN25462 EIPA 1154-25-2 EIPA (L593754) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
CSN21438 Disopyramide   3737-09-5 Disopyramide can block sodium channel it is a class IA antiarrhythmic drug
CSN20559 Cariporide   159138-80-4 Cariporide is a selective inhibitor of NaH exchanger isoform 1 NHE1 with IC50 value of 005 M with cardioprotective and antiarrhythmic effects
CSN16283 Carbamazepine   298-46-4 Carbamazepine is a blocker of sodium channel with IC50 of 131 M in rat brain synaptosomes. It is an anticonvulsant drug.
CSN11492 Camostat Mesilate 59721-29-8 Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trypsin, prostasin and matriptase.
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