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Sodium Channel

Sodium Channel

Cat. No. Product Name CAS No. Information
CSN17315 XEN907 912656-34-9 XEN907 is a spirooxindole NaV17 blocker inhibits hNaV17 with IC50 of 3 nM
CSN16312 Sodium Channel Inhibitor 1 1198117-23-5 Sodium Channel inhibitor1 one of 3-Oxoisoindoline-1-carboxamides is a selective voltage-gated sodium channel for pain treatment
CSN22177 Sodium Channel Inhibitor 2 653573-60-5 Sodium Channel inhibitor 2 is a sodium channel blocker extracted from patent WO 2004011439 A2 compound 3c
CSN11872 Rufinamide   106308-44-5 Rufinamide, an antiepileptic agent, is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS).
CSN24189 Rimeporide 187870-78-6 Rimeporide is a potent and selective Na+/H+ exchanger (NHE1) inhibitor.
CSN12584 Riluzole   1744-22-5 Riluzole is an antagonist of glutamate that used as an anticonvulsant. It can prolong the survival of patients with amyotrophic lateral sclerosis.
CSN11774 Procaine   59-46-1 Procaine, a benzoic acid derivative, is an anesthetic drug through targeting multiple proteins.
CSN11719 Pilsicainide 88069-67-4 Pilsicainide is a sodium channel blocker and an antiarrhythmic agent and a drug to treat cardiac arrhythmias in Japan
CSN16772 Phenytoin Sodium   630-93-3 Phenytoin sodium is a stabilizer of inactive voltage-gated sodium channel
CSN12795 Phenytoin 57-41-0 Phenytoin is an inactive voltage-gated sodium channel stabilizer.
CSN18533 PH-064 892546-37-1 PH-064 is a sodium channel inhibitor
CSN13891 PF-05089771 1235403-62-9 PF-05089771 is a Nav17 channel blocker with an IC50 of 86 nM
CSN22144 PF-04531083 1079400-07-9 PF 04531083 is a selective NaV18 blocker and used for the research of neuropathicinflammatory pain
CSN16737 Oxcarbazepine   28721-07-5 Oxcarbazepine is a voltage-gated sodium channel blocker with IC50 of 160 M and it is used for the treatment of partial seizure
CSN17076 Nicainoprol 76252-06-7 Nicainoprol is a sodium channels blocker which is used as an antiarrhythmic agent
CSN21275 NHE3-IN-1 632355-68-1 NHE3-IN-1 is a sodiumproton exchanger type 3 NHE-3 inhibitor extracted from patent WO 2011019784 A1
CSN11533 Nefopam HCl   23327-57-3 Nefopam a non-opioid analgesic drug is blocker of voltage-gated sodium channel and inhibitor of serotonin dopamine and noradrenaline reuptake It is used to relieve pain
CSN17697 Nav1.7-IN-2 1332295-35-8 Nav17-IN-2 is an inhibitor of voltage-gated sodium channels Nav in particular Nav 17 with IC50 of 80 nM
CSN16914 Nav1.7 Inhibitor 1355631-24-1 Nav17 inhibitor is a sulfonamide derivative with potent Nav17 inhibition activity
CSN10544 Moricizine 31883-05-3 Moricizine is an antiarrhythmia agent used primarily for ventricular rhythm disturbances
CSN10095 Mexiletine HCl   5370-01-4 Mexiletine hydrochloride is a non-selective blocker of voltage-gated sodium channel It blongs to the anti-arrhythmic compounds of class IB
CSN12998 Lamotrigine   84057-84-1 Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition.
CSN18204 ICA-121431 313254-51-2 ICA-121431 is a nanomolar potent small molecule Nav17 channel inhibitor with IC50 of 19 nM for rat Nav17 but no inhibition on human monkey and dog Nav17
CSN16320 GS-967   1262618-39-2 GS-967 is a selective inhibitor of cardiac late sodium current late INa The IC50 values in ventricular myocytes and isolated hearts are 013 M and 021 M
CSN19828 Funapide 1259933-16-8 Funapide is an analgesic agent which may be useful for the treatment of a variety of chronic pain conditions.
CSN21301 FR183998 239440-20-1 FR183998 free base is a potent NaH-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
CSN11018 Flecainide Acetate 54143-56-5 Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav15 sodium channel in the heart causing prolongation of the cardiac action potential
CSN11017 Flecainide 54143-55-4 Flecainide acetate a class Ic antiarrhythmic agent can block the Nav15 sodium channel and inhibit ryanodine receptor 2 RyR2 It is used to prevent and treat tachyarrhythmias
CSN20530 Eniporide 176644-21-6 Eniporide is an inhibitor of NaH exchange that prevents ischemic Na overload
CSN10881 Dyclonine HCl   536-43-6 Dyclonine hydrochloride is the hydrochloride form of dyclonine which can reversibly bind to activated sodium channels on the neuronal membrane It is an anaesthetic found in sucrets
CSN13878 CNV1014802 934240-30-9 CNV1014802 is a blocker of Nav1.7 sodium channel.
CSN15719 CNV1014802 HCl 934240-31-0 CNV1014802 hydrochloride is a blocker of Nav1.7 sodium channel with analgesic effects.
CSN20559 Cariporide   159138-80-4 Cariporide is a selective inhibitor of NaH exchanger isoform 1 NHE1 with IC50 value of 005 M with cardioprotective and antiarrhythmic effects
CSN16283 Carbamazepine   298-46-4 Carbamazepine is a blocker of sodium channel with IC50 of 131 M in rat brain synaptosomes. It is an anticonvulsant drug.
CSN11492 Camostat Mesilate 59721-29-8 Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trypsin, prostasin and matriptase.
CSN16674 Benzocaine   94-09-7 Benzocaine the ethyl ester of p-aminobenzoic acid PABA inhibits voltage-dependent sodium channels VDSCs on the neuron membrane and used as a local anesthetic
CSN18717 Benzocaine HCl 23239-88-5 Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings
CSN20028 AMG8379 1642112-31-9 AMG8379 is a potent and selective small molecule sulfonamide antagonist of the voltage-gated sodium channel NaV17
CSN11757 Ambroxol HCl   23828-92-4 Ambroxol hydrochloride is an inhibitor of neuronal Na channels It inhibits TTX-resistant and sensitive Na currents with IC50 of 352 M tonic225 M phasic block and 100 M respectively
CSN16841 (-)-Sparteine 90-39-1 --Sparteine is a class 1a antiarrhythmic agent and a sodium channel blocker
CSN12884 (-)-Sparteine Sulfate Pentahydrate 6160-12-9 (-)-Sparteine sulfate is a class 1a antiarrhythmic agent and a sodium channel blocker.
CSN22716 BIX NHE1 Inhibitor 1204329-34-9
CSN23212 Zoniporide 2HCl 241799-10-0
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