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Smurf1 and Smurf2 (Smurfs) are two closely related C2-WW-HECT domain E3 ubiquitin ligases, belonging to the NEDD4 subfamily of HECT type E3s. Smurf1 and Smurf2 were originally identified as negative regulators of BMP/TGF-β signaling pathways.

Smurf

Cat. No. Product Name CAS No. Information
CSN24085 Smurf1-IN-A01   1007647-73-5 Smurf1-IN-A01 is an inhibitor of negatively regulatory factor Smurf1 for promoting bone formation.
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