Smurf1 and Smurf2 (Smurfs) are two closely related C2-WW-HECT domain E3 ubiquitin ligases, belonging to the NEDD4 subfamily of HECT type E3s. Smurf1 and Smurf2 were originally identified as negative regulators of BMP/TGF-β signaling pathways.
|Cat. No.||Product Name||CAS No.||Information|
|CSN24085||Smurf1-IN-A01||1007647-73-5||Smurf1-IN-A01 is an inhibitor of negatively regulatory factor Smurf1 for promoting bone formation.|