Sirtuin
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN25238 | UBCS039 | 358721-70-7 | UBCS039 is a specific Sirtuin 6 activator which showed robust activating effects on Sirt6-dependent H3K18ac deacetylation of both full-length histone proteins and complete HeLa nucleosomes. |
CSN12331 | Triacetylresveratrol | 42206-94-0 | Triacetylresveratrol is a prodrug of resveratrol with multiple targets including sirt, COX, IKK and LOX, etc.. |
CSN18940 | SRT3025 HCl | 2070015-26-6 | SRT3025 HCl is an orally available sirtuin modulator. |
CSN24314 | SRT1720 2HCl | 1001645-58-4 | SRT1720 2HCl is a selective SIRT1 activator. |
CSN12889 | Splitomicin | 5690-03-9 | Splitomicin is a selective NAD-dependent histone deacetylase Sir2p inhibitor with IC50 of 60 M showing a higher activity in a cell-based assay |
CSN12523 | Sirtinol | 410536-97-9 | Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 M and 38 M in cell-free assays respectively |
CSN25457 | OSS_128167 | 887686-02-4 | OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects. |
CSN16796 | Nicotinamide | 98-92-0 | Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP |
CSN18677 | Fisetin | 528-48-3 | Fisetin is an active flavonol that can be used in the synthesis of pharmaceutical with anti-inflammatory and antiproliferative activities |
CSN10146 | EX-527 | 49843-98-3 | EX-527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits 200-fold selectivity against SIRT2 and SIRT3. |
CSN10815 | Dihydrocoumarin | 119-84-6 | Dihydrocoumarin, a natural product isolated and purified from the leaves of Southern sweet-grass., is widespread used as a flavoring agent in beverages, gelatins, puddings, candy, and other food items. It is also as a fragrance in perfumes, creams, and cosmetics. |
CSN19942 | Agrimol B | 55576-66-4 | Agrimol B is a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb. |
CSN20654 | 3-TYP | 120241-79-4 | 3-TYP is a selective inhibitor of SIRT3 |