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Sirtuin

Sirtuin

Cat. No. Product Name CAS No. Information
CSN25238 UBCS039 358721-70-7 UBCS039 is a specific Sirtuin 6 activator which showed robust activating effects on Sirt6-dependent H3K18ac deacetylation of both full-length histone proteins and complete HeLa nucleosomes.
CSN12331 Triacetylresveratrol   42206-94-0 Triacetylresveratrol is a prodrug of resveratrol with multiple targets including sirt, COX, IKK and LOX, etc..
CSN18940 SRT3025 HCl 2070015-26-6 SRT3025 HCl is an orally available sirtuin modulator.
CSN24314 SRT1720 2HCl 1001645-58-4 SRT1720 2HCl is a selective SIRT1 activator.
CSN12523 Sirtinol 410536-97-9 Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 M and 38 M in cell-free assays respectively
CSN19216 SirReal2 709002-46-0 SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM
CSN25457 OSS_128167 887686-02-4 OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects.
CSN16796 Nicotinamide   98-92-0 Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP
CSN18677 Fisetin   528-48-3 Fisetin is an active flavonol that can be used in the synthesis of pharmaceutical with anti-inflammatory and antiproliferative activities
CSN10146 EX-527   49843-98-3 EX-527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits 200-fold selectivity against SIRT2 and SIRT3.
CSN10815 Dihydrocoumarin   119-84-6 Dihydrocoumarin, a natural product isolated and purified from the leaves of Southern sweet-grass., is widespread used as a flavoring agent in beverages, gelatins, puddings, candy, and other food items. It is also as a fragrance in perfumes, creams, and cosmetics.
CSN19942 Agrimol B 55576-66-4 Agrimol B is a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb.
CSN20654 3-TYP   120241-79-4 3-TYP is a selective inhibitor of SIRT3
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