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SIK

SIK

Cat. No. Product Name CAS No. Information
CSN24297 YKL 06-061 2172617-15-9 YKL 06-061 is a pan-SIK inhibitor with IC50 values of 6.56nM, 1.77nM and 20.5nM for SIK1, SIK2 and SIK3, respectively.
CSN14948 Pterosin B 34175-96-7 Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
CSN17882 HG-9-91-01 1456858-58-4 HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.
CSN24497 ARN-3236 1613710-01-2 ARN-3236 is a selective SIK2 inhibitor with IC50 values of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively.
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