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SIK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN28431 | YKL-05-099 | 1936529-65-5 | YKL-05-099 is a selective SIK inhibitor with IC50 values of 10 nM, 40 nM and 30 nM for SIK1, SIK2 and SIK3, respectively. |
| CSN24297 | YKL-06-061 | 2172617-15-9 | YKL 06-061 is a pan-SIK inhibitor with IC50 values of 6.56nM, 1.77nM and 20.5nM for SIK1, SIK2 and SIK3, respectively. |
| CSN33249 | WH-4-025 | 1876463-35-2 | WH-4-025 is a SIK inhibitor extracted from WO2016023014 A2. |
| CSN14948 | Pterosin B | 34175-96-7 | Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| CSN25230 | ODM-203 | 1430723-35-5 | ODM-203 is a selective inhibitor of FGFR and VEGFR with IC50 values of 11, 16, 6, 35nM for recombinant FGFR1-4 and 26, 9, 5nM for VEGFR1-3, respectively. |
| CSN17882 | HG-9-91-01 | 1456858-58-4 | HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. |
| CSN24497 | ARN-3236 | 1613710-01-2 | ARN-3236 is a selective SIK2 inhibitor with IC50 values of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. |
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