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SGLT
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22533 | Velagliflozin | 946525-65-1 | Velagliflozin is an orally available sodium-glucose cotransporter 2 SGLT2 inhibitor with anti-diabetic activity |
| CSN17552 | Tofogliflozin Hydrate | 1201913-82-7 | Tofogliflozin is a potent and highly specific sodiumglucose cotransporter 2SGLT2 inhibitor with Ki values of 29 149 and 64 nM for human rat and mouse SGLT2 |
| CSN16054 | Tofogliflozin | 903565-83-3 | Tofogliflozin is a potent and highly specific sodiumglucose cotransporter 2 SGLT2 inhibitor with Ki values of 29 149 and 64 nM for human rat and mouse SGLT2 |
| CSN20626 | TA-1887 | 1003005-29-5 | TA-1887 is a highly potent and selective hSGLT2 inhibitor with pronounced antihyperglycemic effects in high-fat diet-fed KK HF-KK mice |
| CSN11698 | Phloridzin | 60-81-1 | Phlorizin is an inhibitor of hSGLT1 Ki300 nM and hSGLT2 Ki 39 nM It can be found in a number of fruit trees |
| CSN11697 | Phloretin | 60-82-2 | Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree. |
| CSN15831 | PF-04971729 | 1210344-57-2 | PF-04971729 is a selective sodium-dependent glucose cotransporter SGLT inhibitor which selectively targets SGLT2 |
| CSN15683 | LX4211 | 1018899-04-1 | LX4211 is an inhibitor of SGLT2 and SGLT1 with antidiabetic activity. |
| CSN19739 | LX2761 | 1610954-97-6 | LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control LX2761 was designed to remain in the intestine after oral delivery to inhibit SGLT1 locally without affecting the SGLT12 mechanism in the kidney |
| CSN19830 | Luseogliflozin | 898537-18-3 | Luseogliflozin is a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2 inhibitor). |
| CSN21112 | Licogliflozin | 1291094-73-9 | Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor |
| CSN15422 | Kushenol X | 254886-77-6 | Kushenol X is a natural product isolated and purified from the roots of Sophora flavescens Ait. exhibiting inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). |
| CSN22259 | Ipragliflozin (L-Proline) | 951382-34-6 | Ipragliflozin L-Proline selectively inhibits SGLT2 with IC50 of 28 nM |
| CSN16022 | Ipragliflozin | 761423-87-4 | Ipragliflozin is a selective inhibitor of SGLT2 with IC50 of 14 nM for hSGLT2 |
| CSN20593 | Henagliflozin | 1623804-44-3 | Henagliflozin is a sodium glucose co-tranporter 2 inhibitor with the IC50 values against human SGLT2 and SGLT1 were 238 and 4324 nmolL respectively and is used for treating patients with type 2diabetes mellitus |
| CSN23815 | Ertugliflozin L-pyroglutamic Acid | 1210344-83-4 | Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2]. |
| CSN13801 | Empagliflozin | 864070-44-0 | Empagliflozin is a selective inhibitor of SGLT-2 with IC50 of 31 nM |
| CSN13871 | Dapagliflozin Propanediol Hydrate | 960404-48-2 | Dapagliflozin propanediol is an inhibitor of SGLT2 that is used for the treatment of of type 2 diabetes mellitus |
| CSN12342 | Dapagliflozin | 461432-26-8 | Dapagliflozin is a selective inhibitor of SGLT2 with EC50 of 11 nM which is used to treat type 2 diabetes mellitus |
| CSN16237 | Canagliflozin Hemihydrate | 928672-86-0 | Canagliflozin selectively inhibits SGLT2 with IC50 of 2.2 nM. |
| CSN12954 | Canagliflozin | 842133-18-0 | Canagliflozin is a novel C-glucoside with thiophene ring. |
| CSN17473 | Bexagliflozin | 1118567-05-7 | Bexagliflozin is an inhibitor of SGLT2 with IC50 value of 2 nM. |
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