SGLT
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN11698 | Phloridzin | 60-81-1 | Phlorizin is an inhibitor of hSGLT1 Ki300 nM and hSGLT2 Ki 39 nM It can be found in a number of fruit trees |
CSN11697 | Phloretin | 60-82-2 | Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree. |
CSN15831 | PF-04971729 | 1210344-57-2 | PF-04971729 is a selective sodium-dependent glucose cotransporter SGLT inhibitor which selectively targets SGLT2 |
CSN23815 | Ertugliflozin L-pyroglutamic Acid | 1210344-83-4 | Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2]. |
CSN12342 | Dapagliflozin | 461432-26-8 | Dapagliflozin is a selective inhibitor of SGLT2 with EC50 of 11 nM which is used to treat type 2 diabetes mellitus |
CSN12954 | Canagliflozin | 842133-18-0 | Canagliflozin is a novel C-glucoside with thiophene ring. |