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SGLT

SGLT

Cat. No. Product Name CAS No. Information
CSN22533 Velagliflozin 946525-65-1 Velagliflozin is an orally available sodium-glucose cotransporter 2 SGLT2 inhibitor with anti-diabetic activity
CSN17552 Tofogliflozin (hydrate) 1201913-82-7 Tofogliflozin is a potent and highly specific sodiumglucose cotransporter 2SGLT2 inhibitor with Ki values of 29 149 and 64 nM for human rat and mouse SGLT2
CSN16054 Tofogliflozin 903565-83-3 Tofogliflozin is a potent and highly specific sodiumglucose cotransporter 2 SGLT2 inhibitor with Ki values of 29 149 and 64 nM for human rat and mouse SGLT2
CSN20626 TA-1887 1003005-29-5 TA-1887 is a highly potent and selective hSGLT2 inhibitor with pronounced antihyperglycemic effects in high-fat diet-fed KK HF-KK mice
CSN11698 Phlorizin 60-81-1 Phlorizin is an inhibitor of hSGLT1 Ki300 nM and hSGLT2 Ki 39 nM It can be found in a number of fruit trees
CSN11697 Phloretin   60-82-2 Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree.
CSN15831 Ertugliflozin 1210344-57-2 PF-04971729 is a selective sodium-dependent glucose cotransporter SGLT inhibitor which selectively targets SGLT2
CSN15683 Sotagliflozin 1018899-04-1 LX4211 is an inhibitor of SGLT2 and SGLT1 with antidiabetic activity.
CSN19739 LX2761 1610954-97-6 LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control LX2761 was designed to remain in the intestine after oral delivery to inhibit SGLT1 locally without affecting the SGLT12 mechanism in the kidney
CSN21112 Licogliflozin 1291094-73-9 Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor
CSN16003 α-L-Rhamnose monohydrate   6155-35-7 L-Rhamnose, a natural product isolated and purified from the flowers of Scphora japonica L., increases serum propionate after long-term supplementation, but lactulose does not raise serum acetate, has anticancer potential, they exert a significant suppressive effect on tumour growth, and exhibits potent excellent sodium-glucose transporter (SGLT1 and SGLT2) inhibition activity.
CSN15422 Kushenol X 254886-77-6 Kushenol X is a natural product isolated and purified from the roots of Sophora flavescens Ait. exhibiting inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).
CSN22259 Ipragliflozin (L-Proline)   951382-34-6 Ipragliflozin L-Proline selectively inhibits SGLT2 with IC50 of 28 nM
CSN16022 Ipragliflozin   761423-87-4 Ipragliflozin is a selective inhibitor of SGLT2 with IC50 of 14 nM for hSGLT2
CSN20593 Henagliflozin 1623804-44-3 Henagliflozin is a sodium glucose co-tranporter 2 inhibitor with the IC50 values against human SGLT2 and SGLT1 were 238 and 4324 nmolL respectively and is used for treating patients with type 2diabetes mellitus
CSN23815 Ertugliflozin L-pyroglutamic acid 1210344-83-4 Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2].
CSN13801 Empagliflozin   864070-44-0 Empagliflozin is a selective inhibitor of SGLT-2 with IC50 of 31 nM
CSN13871 Dapagliflozin ((2S)-1,2-propanediol, hydrate)   960404-48-2 Dapagliflozin propanediol is an inhibitor of SGLT2 that is used for the treatment of of type 2 diabetes mellitus
CSN12342 Dapagliflozin 461432-26-8 Dapagliflozin is a selective inhibitor of SGLT2 with EC50 of 11 nM which is used to treat type 2 diabetes mellitus
CSN16237 Canagliflozin hemihydrate   928672-86-0 Canagliflozin selectively inhibits SGLT2 with IC50 of 2.2 nM.
CSN12954 Canagliflozin 842133-18-0 Canagliflozin is a novel C-glucoside with thiophene ring.
CSN17473 Bexagliflozin (EGT1442) 1118567-05-7 Bexagliflozin is an inhibitor of SGLT2 with IC50 value of 2 nM.
CSN51385 Enavogliflozin 1415472-28-4
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