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Sesquiterpenoids

Sesquiterpenoids

Cat. No. Product Name CAS No. Information
CSN13998 Xanthatin 26791-73-1 Xanthatin, a natural product isolated and purified from the fruits of Xanthium sibiricum with cytotoxic, antibacterial and antifungal activities, can inhibit murine melanoma B16-F10 cell proliferation possibly associated with activation of Wnt-catenin pathway and its activity against melanoma tumor might also be relevant to inhibition of angiogenesis.
CSN14458 Vomifoliol 23526-45-6 Vomifoliol, a natural product isolated and purified from the herbs of Vitis vinifera, can cause as much stomatal closure in epidermal strips of Eichhornia crassipes (Mart.) Solms as ABA at identical concentrations.
CSN15519 Vibralactone D 1251748-32-9 Vibralactones D is a natural product isolated and purified from cultures of the basidiomycete Boreostereum vibrans, showing weak inhibitory activities against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD) with IC(50) values of 85.7 mM (human HSD1), 295.2 mM (mouse HSD1), and 87.1 mM (human HSD2).
CSN13958 Tussilagone 104012-37-5 Tussilagone, a natural product isolated and purified from the flower of Tussilago farfara, has potential treatment of neuro-inflammatory diseases through the inhibition of overproduction of nitric oxide and prostaglandin E(2) .
CSN14470 Torilolone 13018-09-2 Torilolone, a natural product isolated and purified from the herbs of Cnidium monnieri, show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 value is 20.6 - 1.86.
CSN13977 Spathulenol 6750-60-3 Spathulenol, a natural product isolated and purified from the herbs of Salvia sclarea, has immunoinhibitory effect and shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
CSN14937 Scabertopin 185213-52-9 Scabertopin, a natural product isolated and purified from the herbs of Elephantopus scaber Linn., exhibits significant antitumor effect in vitro in a concentration-dependent manner.
CSN14454 Santamarine 4290-13-5 Santamarine, a natural product isolated and purified from the root of Dolomiaea souliei (Franch.) Shih, with significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine, and shows anti-bactericidal activity against clinical strains of Mycobacterium tuberculosis.
CSN14938 Piptocarphin A 76248-63-0 Piptocarphin A, a natural product isolated and purified from the herbs of Vernonia volkameriifolia, shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 mM .
CSN11611 Onitin 53823-02-2 Onitin, a natural product isolated and purified from the herbs of Onychium japonicum, exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
CSN11573 Nootkatone   4674-50-4 Nootkatone is a natural organic compound, used as insecticide and food additive.
CSN11543 Nerolidol 7212-44-4 Nerolidol, a natural product isolated and purified from the peel of Citrus maxima, shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presence of oxidative lesions.
CSN11462 Mollugin 55481-88-4 Mollugin, a natural product isolated and purified from the roots of Rubia cordifolia L., may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
CSN14455 Macrocarpal B 142698-60-0 Macrocarpal B is a natural product isolated and purified from the branch of Eucalyptus globulus with antibacterial and antifouling activities.
CSN14694 Lipiferolide 41059-80-7 Lipiferolide, a natural product isolated and purified from the herbs of Liriodendron tulipifera with antiplasmodial activity, is an inhibitor of farnesyl protein transferase, inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, and possesses cytotoxic activity against KB cells.
CSN13549 Linderene 26146-27-0 Linderene is a natural product isolated and purified from the roots of Lindera aggregata (Sims) Kosterm.
CSN19969 Linderane 13476-25-0 Linderane, a natural product isolated and purified from the roots of Lindera aggregata( Sims) Kosterm, is an inactivator of CYP2C9.
CSN13180 Linderalactone 728-61-0 Linderalactone, a natural product isolated and purified from the roots of Lindera aggregata, shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLPCB, values of IC50 is 8.48 gmL.
CSN14473 Leucomisine 17946-87-1 Leucomisine is a natural product isolated and purified from Artemisia leucodes.
CSN14701 Isodeoxyelephantopin 38927-54-7 Isodeoxyelephantopin, a natural product isolated and purified from the herbs of Elephantopus scaber Linn., exerts antitumor effects on several cancer cells by inducing apoptosis, cell cycle arrest, and inhibiting proliferation, and enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kappaB-regulated gene expression.
CSN14457 Isocostic Acid 69978-82-1 Isocostic acid is a natural product isolated and purified from the roots of Aucklandia lappa Decne..
CSN14073 Ilicic Acid 4586-68-9 Ilicic acid is a natural product isolated and purified from the bark of Laggera pterodonta with anti-hyperglycemic and anti-inflammatory activities.
CSN13571 Humulene Epoxide II 19888-34-7 Humulene epoxide II, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe, has mildly phytotoxic and antifungal activities.
CSN16274 Fraxinellone   28808-62-0 Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2 channel, while dictamine relaxed the rat aorta by suppressing the Ca2 influx through both voltage-dependent and receptor-operated Ca2 channels, and can dramatically induce apoptosis of activated peripheral CD4() T cells in vivo, consequently resulting in less CD4() T-cell activation and infiltration to the liver.
CSN14475 Eupatoriopicrin 6856-01-5 Eupatoriopicrin is a natural product isolated and purified from Eupatorium cannabinum L..
CSN10974 Eupatolide 6750-25-0 Eupatolide, a natural product isolated and purified from the herbs of Salvia sclarea with immunoinhibitory effect, inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6.
CSN14468 Deoxyelephantopin 29307-03-7 Deoxyelephantopin is a natural product isolated and purified from the herbs of Elephantopus scaber Linn. with hepatoprotective and antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3p53p21 signaling, MAPK pathway, PI3kAktmTOR pathway, caspase cascades, and ROS .
CSN12303 Dehydrocostus Lactone   477-43-0 Dehydrocostus Lactone a naturally occuring sesquiterpene lactone in the roots of Saussurea lappa with anti-inflammatory activity.
CSN14137 Curzerenone 20493-56-5 Curzerenone, a natural product isolated and purified from the rhizome of Curcuma zedoaria, has slightly effective against E. coli (IZ 10.8 0.52. Curzerenone and holds great promise for use in chemopreventive and chemotherapeutic strategies.
CSN14466 Corchoionoside C 185414-25-9 Corchoionoside C, a natural product isolated and purified from the herbs of Polygonum hydropiper with antifungal, anti-allergic and anti-histaminic effects, inhibits the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
CSN16181 Carabrone 1748-81-8 Carabrone, a natural product isolated and purified from the herbs of Carpesium abrotanoides, exhibit antifungal activities in vitro or in vivo.
CSN14708 Bakkenolide B 18455-98-6 Bakkenolide B, a natural product isolated and purified from the leaves of Peatasites japonicus, has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
CSN13607 Atractylone 6989-21-5 Atractylone, a natural product isolated and purified from the roots of Atractylodes macrocephala, has inhibitory effects on mast cell-mediated allergic reactions, it regulates the degranulation of mast cell, proves its potential in the treatment of mast cell-mediated allergic reactions.
CSN13071 Artesunate   88495-63-0 Artesunate is a part of the artemisinin group of agents with an IC50 of 5 M for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and EXP1 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro.
CSN18461 Arglabin 84692-91-1 Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella and an anticancer natural compound.
CSN16394 Alantolactone   546-43-0 Alantolactone is a sesquiterpene lactone with potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway.
CSN14706 8α-(2-Methylacryloyloxy)hirsutinolide 13-O-Acetate 67667-71-4 8-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate is a natural product isolated and purified from the herbs of Vernonia cinerea showing inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
CSN13034 6,8-Cyclo-1,4-Eudesmanediol 213769-80-3 6,8-Cyclo-1,4-eudesmanediol is a natural product isolated and purified from the branchs of Eucalyptus robusta Smith.
CSN13389 4(15),5,10(14)-Germacratrien-1-Ol 81968-62-9 4(15),5,10(14)-Germacratrien-1-ol is a natural product isolated and purified from the roots of Acorus calamus L..
CSN13027 3,4-Dihydro-2,2-Dimethyl-2H-Naphtho[1,2-B]pyran 16274-33-2 3,4-Dihydro-2,2-dimethyl-2H-naphtho1,2-bpyran is a natural product isolated and purified from the herbs of Catalpa ovata.
CSN13248 1-Hydroxy-2-Prenylnaphthalene 16274-34-3 1-Hydroxy-2-prenylnaphthalene is a natural product isolated and purified from the herbs of Catalpa ovata.
CSN13237 1,4,7-Eudesmanetriol 145400-02-8 1,4,7-Eudesmanetriol is a natural product isolated and purified from the branch of Eucalyptus globulus.
CSN13290 1,10:4,5-Diepoxy-7(11)-Germacren-8-One 32179-18-3 1,104,5-Diepoxy-7(11)-germacren-8-one is a natural product isolated and purified from the herbs of Isodon adenantha.
CSN11893 β-Santalol   11031-45-1 -Santalol is a compound of sandalwood oil showing antiinflammatory property by suppressing of lipopolysaccharide-stimulated cytokinechemokine production in skin cells and anti-viral effect against influenza viral replication in vitro.
CSN20351 β-Elemene 515-13-9 -Elemene is a natural sesquiterpene found in various plants and imparts floral aromas to some plants. This compound has been reported to inhibit the proliferation of a wide range of tumors.
CSN14948 Pterosin B 34175-96-7
CSN13554 Eupalinolide B 877822-41-8
CSN14136 Cryptomeridiol 4666-84-6
CSN14461 Isofuranodiene 57566-47-9
CSN16456 Atractylenolide III 73030-71-4
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