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Ser/Thr Protease

Ser/Thr Protease

Cat. No. Product Name CAS No. Information
CSN23689 (R)-2-((6-((3'-(Aminomethyl)-5-methyl-[1,1'-biphenyl]-3-yl)oxy)-3,5-difluoropyridin-2-yl)oxy)butanoic acid 2271122-53-1 ZK824859 is a new structural class uPA inhibitor with potential effect on treating multiple sclerosis.
CSN23329 UK-371804 HCl 256476-36-5 UK-371804 HCl is a potent and selective urokinase-type plasmogen activator uPA inhibitor with excellent enzyme potency Ki10 nM and selectivity profile 4000-fold versus tPA and 2700-fold versus plasmin
CSN23618 NSC95682   20035-41-0 NSC95682 is a derivative of bromobenzaldehyde which can inhibit inositol-requiring enzyme 1 IRE-1 with IC50 of 008 M
CSN11508 Nafamostat Mesylate   82956-11-4 Nafamostat mesylate is a synthetic inhibitor of serine protease with anticoagulant activity.
CSN18442 Nafamostat 81525-10-2 Nafamostat is a broad spectrum serine protease inhibitor kallikrein inhibitor and inhibits blood coagulation It is also a possible complement inhibitor
CSN11071 Gabexate Mesylate   56974-61-9 Gabexate mesylate could inhibit trypsin plasmin plasma kallikrein and thrombin with IC50s of 94 M 30 M 41 M and 110 M It has certain anticoagulant effect
CSN25456 Benzamidine HCl 1670-14-0 Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively.
CSN23538 7H-Purin-2-amine   452-06-2 7H-Purin-2-amine isomer of adenine is an inhibitor of protein kinase R PKR with antimetabolite effect
CSN24042 3,4-Dichloroisocoumarin 51050-59-0 3,4 Dichloroisocoumarin is a potent, irreversible inhibitor of serine proteases. It reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. 3,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. 3,4 Dichloroisocoumarin inhibits activation of neutral sphingomyelinase and daunorubicin-triggered apoptosis as well as apoptosis induced by camptothecin in HL-60 cells. 3,4 Dichloroisocoumarin inhibits migration of eosinophils through basement membrane components in vitro. 3,4 Dichloroisocoumarin does not affect thiol proteases and metalloproteases. 3,4 Dichloroisocoumarin does not exhibit any activity towards β-lactamases. 3,4 Dichloroisocoumarin is an inhibitor of Chymotrypsin and Trypsin.
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