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RSK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN20281 | SL 0101-1 | 77307-50-7 | SL0101 is a selective inhibitor of ribosomal S6 kinase RSK IC50 89 nM for RSK2 which does not inhibit upstream kinases such as MEK Raf and PKC SL0101 Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line |
| CSN15894 | PF-4708671 | 1255517-76-0 | PF-4708671 is an inhibitor of S6K1 p70 ribosomal S6 kinase 1 with Ki and IC50 of 20 nM and 160 nM respectively |
| CSN21078 | M2698 | 1379545-95-5 | MSC2363318A, also known as M2698, is an orally available inhibitor of the serine/threonine protein kinases ribosomal protein S6 Kinase (p70S6K) and Akt (protein kinase B), with potential antineoplastic activity. |
| CSN17452 | LY-2584702 tosylate salt | 1082949-68-5 | LY2584702 tosylate salt is an inhibitor of p70S6K signaling and can prevent the phosphorylation of S6 subunit of ribosomes |
| CSN15762 | LY-2584702 free base | 1082949-67-4 | LY2584702 is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes |
| CSN17451 | LY-2584702 hydrochloride | 1082948-81-9 | LY2584702 HCl is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes. |
| CSN17965 | LJI308 | 1627709-94-7 | LJI308 is a potent pan-RSK inhibitor with IC50 of 6 nM 4 nM and 13 nM for RSK1 RSK2 and RSK3 respectively |
| CSN17966 | LJH685 | 1627710-50-2 | LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM 5 nM and 4 nM for RSK1 RSK2 and RSK3 respectively |
| CSN10554 | Carnosol | 5957-80-2 | Carnosol, a natural product isolated and purified from the herbs of Rosmarinus officinalis L., enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. Carnosol may as an agonist of TRPA1 with an EC50 value of 12.46 M. |
| CSN17680 | BIX 02565 | 1311367-27-7 | BIX-02565 is a ribosomal S6 kinase 2 RSK2 inhibitor with an IC50 of 11 nM |
| CSN12314 | BI-D1870 | 501437-28-1 | BI-D1870 is an inhibitor of S6 ribosome which can inhibit RSK1 RSK2 RSK3 RSK4 with IC50 of 31 nM 24 nM 18 nM and 15 nM respectively |
| CSN43417 | FMK-MEA | 1414811-15-6 |
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