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ROS
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN27384 | Urolithin C | 165393-06-6 | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. |
| CSN13774 | Tiopronin | 1953-02-2 | Tiopronin derivative of glycine is used to control the rate of cystine precipitation and excretion It can be used as an antioxidant agent and radical scavenger |
| CSN18690 | Tempol | 2226-96-2 | Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. |
| CSN27569 | Tempo | 2564-83-2 | Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects. |
| CSN12258 | Scutellarein | 529-53-3 | Scutellarin is cytotoxic to cancer cells and could induce DNA damage, metabolic suppression and mitochondrial reactive oxygen species. It has has antioxidant, anti-inflammatory, and antiproliferative biological activities that can be can be found in scutellaria lateriflora. |
| CSN33149 | HPF | 686773-84-2 | ROS Probe, a cell-permeable, photo-stable hydroxyphenyl-substituted fluorescein compound. |
| CSN11731 | Piperlongumine | 20069-09-4 | Piperlongumine a natural alkaloid from Piper longum L increases the level of reactive oxygen species ROS and selectively kills cancer cells It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3KAktmTOR in human breast cancer cells |
| CSN12508 | Oleuropein | 32619-42-4 | Oleuropein is an antioxidant polyphenol isolated from the herb of Olea europaea L |
| CSN24072 | N-Acetylcysteine amide | 38520-57-9 | N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production. |
| CSN51114 | Imeglimin tartrate | 775351-66-1 | Imeglimin is the first in a tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. |
| CSN16950 | Imeglimin | 775351-65-0 | Imeglimin is the first in a tetrahydrotriazine-containing class of oral antidiabetic agents the glimins It has been shown to act on the liver muscle and pancreatic -cells to uniquely target the key defects of type 2 diabetes |
| CSN18429 | Imeglimin hydrochloride | 775351-61-6 | Imeglimin HCl is the first in a tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. |
| CSN11185 | Idebenone | 58186-27-9 | Idebenone a synthetic analog of coenzyme Q10 CoQ10 can protect mitochondrial membranes against lipid peroxidation and also used as a neuroprotective agent |
| CSN21114 | H2DCFDA | 4091-99-0 | H2DCFDA, a cell-permeable fluorogenic probe, is useful to detect reactive oxygen species (ROS) and nitric oxide thus determinate the degree of oxidative stress. |
| CSN26546 | GSK5182 | 877387-37-6 | GSK5182 is a specific inverse agonist for estrogen-related receptor γ. |
| CSN12457 | Gramine | 87-52-5 | Gramine, a naturally occurring indole alkaloid isolated and purified from the herbs of Arundo donax L., has dual effect on the bile acid and sterols cell membrane partitioning activity in vivo, and can activate of antioxidants and inactivative of SOD in M. aeruginosa. Gramine has phytotoxicity on M. aeruginosa may be due to oxidative damage via oxidation of ROS . |
| CSN26380 | Ecabet sodium | 86408-72-2 | Ecabet sodium is currently applied to some gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]. |
| CSN24748 | DMNQ | 6956-96-3 | DMNQ is a 1,4-naphthoquinone with redox cycling property. It increases the formation of superoxide and hydrogen peroxide in cells. |
| CSN16599 | Crocin | 42553-65-1 | Crocin, a natural product isolated and purified from the stigma of Crocus sativus L., can relax smooth muscles with a great potential to be a candidate for the treatment of asthma, protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production, improve toxic effects of DZN via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta, protect rat gastric mucosa against ethanol-induced injury via anti-inflammatory, anti-oxidative, anti-apoptotic and mucin-secretagogue mechanisms that are probably mediated by enhanced PGE2 release, significantly inhibit the growth of HO-8910 cells and arrest them in the G0/G1 phase, and also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3. |
| CSN10376 | BAPTA | 85233-19-8 | BAPTA is an chelator of Ca2 that can suppress intracellular reactive oxygen species ROS BAPTA is used as a neuroprotective agent |
| CSN18374 | ATN-224 | 649749-10-0 | ATN-224 a copper-chelator agent can inhibit intracellular SOD1 with IC50 of 175 nM |
| CSN16436 | Acetylcysteine | 616-91-1 | Acetylcysteine is an inhibitor of ROS and the production of TNF. It is a pharmaceutical drug and nutritional supplement used as mucolytic agent. |
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