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Cat. No.	Product Name	CAS No.	Information
CSN16326	ZCL278	587841-73-4	ZCL278 is a modulator of Cdc42 through directly binding to Cdc42 with Kd of 114 M
CSN15778	XRP44X	729605-21-4	XRP44X is an inhibitor of Ras-Net Elk-3 pathway with IC50 of 10 nM - 20 nM and could inhibit the phosphorylation of ERK1ERK2
CSN17256	RBC8	361185-42-4	RBC8 is an inhibitor of GTPases RalA and RalB with IC50 of 35 M in cell assay
CSN19268	NSC 23766	733767-34-5	NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase with IC50 of 50 M and does not inhibit the closely related targets Cdc42 or RhoA
CSN16332	ML141	71203-35-5	ML141 is a reversible and selective inhibitor of Cdc42 GTPase with IC50 of 200 nM
CSN18462	MDK-3017	84783-01-7	MDK-3017 is a K-Ras inhibitor, by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.
CSN19755	MBQ-167	2097938-73-1	MBQ-167 is a dual Rac and Cdc42 inhibitor potential to be developed as an anticancer drug
CSN15978	Kobe2602	454453-49-7	Kobe2602 is an effective small-molecule compound inhibiting RasRaf interaction by SBDD exhibiting potent activity to competitively inhibit the binding of H-RasGTP to c-Raf-1 RBD with a Ki value of 149 55 M
CSN15977	Kobe0065	436133-68-5	Kobe0065 inhibits the binding of H-RasGTP to c-Raf-1 RBD with Ki of 46 13 M
CSN17973	K-Ras G12C-IN-3	1629268-19-4	K-Ras G12C-IN-3 is an irreversible inhibitor of mutant K-ras G12C
CSN17972	K-Ras G12C-IN-2	1629267-75-9	K-Ras G12C-IN-2 is an irreversible inhibitor of mutant K-ras G12C
CSN17971	K-Ras G12C-IN-1	1629265-17-3	K-Ras G12C-IN-1 is an irreversible inhibitor of mutant K-ras G12C
CSN16411	EHT 1864	754240-09-0	EHT 1864 dihydrochloride is an inhibitor of Rac1 Kd 40 nM Rac1b Kd 50 nM Rac2 Kd 60 nM and Rac3 Kd 250 nM
CSN17155	EHop-016	1380432-32-5	EHop-016 is an inhibitor of Rac1 with IC50 of 11 M in MDA-MB-435 cells
CSN16977	CASIN	425399-05-9	CASIN is an inhibitor of GTPase Cdc42 with IC50 of 2 M that can generat a rejuvenated phenotype of HSCs
CSN17244	BQU57	1637739-82-2	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth similar to depletion of Ral by siRNA
CSN10366	Azathioprine	446-86-6	Azathioprine can inhibit GTP-binding protein Rac1 activation and purine synthesis. Azathioprine is used to treat organ transplantation and autoimmune diseases.
CSN18987	ARS-853	1629268-00-3	ARS-853 is an inhibitor of KRAS G12C with IC50 of 25 M
CSN21239	ARS-1630	1698055-86-5	ARS-1630 is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1
CSN21101	ARS-1620	1698055-85-4	ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics
CSN21238	ARS-1323	1698024-73-5	ARS-1323 is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1
CSN24158	AMG 510	2296729-00-3	AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor, which locks KRAS G12C in an inactive GDP-bound state. AMG-510 selectively targets the KRAS p.G12C mutant and shows anti-tumor activity.
CSN18970	6H05 Trifluoroacetate	2061344-88-3	6H05 trifluoroacetate is a selective and allosteric inhibitor of oncogenic mutant K-Ras G12C
CSN17885	6H05	1469338-01-9	6H05 is a selective and allosteric inhibitor of oncogenic mutant K-Ras G12C
CSN24205	1A-116	1430208-73-3	1A-116 is a specific Rac1 inhibitor.
CSN13741	K-Ras(G12C) Inhibitor 12	1469337-95-8
CSN16515	NSC 23766 3HCl	1177865-17-6

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Ras Items: 1–10 of Show: 50 20 50 100

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Ras

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