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Ras

Ras

Cat. No. Product Name CAS No. Information
CSN16630 Schisantherin A 58546-56-8 Schisantherin A is a natural product isolated and purified from the herbs of Chelidonium majus with anti-microbial, anti-oxidant and anti-inflammatory properties, and is a specific inhibitor of Rac1b.
CSN16625 Sanguinarine 2447-54-3 Sanguinarine is a benzophenanthridine alkaloid which has anti-microbial, anti-oxidant and anti-inflammatory properties. It is a specific inhibitor of Rac1b, and with potential antitumor activity.
CSN16332 ML141   71203-35-5 ML141 is a reversible and selective inhibitor of Cdc42 GTPase with IC50 of 200 nM
CSN18462 MDK-3017 84783-01-7 MDK-3017 is a K-Ras inhibitor, by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.
CSN27182 LC-2 2502156-03-6 LC-2 is the first PROTAC capable of degrading endogenous KRAS(G12C). It covalently binds KRASG12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRASG12C degradation leading to suppression of MAPK signaling in both homozygous and heterozygous KRASG12C cell lines.
CSN10366 Azathioprine   446-86-6 Azathioprine can inhibit GTP-binding protein Rac1 activation and purine synthesis. Azathioprine is used to treat organ transplantation and autoimmune diseases.
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