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Quinones

Quinones

Cat. No. Product Name CAS No. Information
CSN17088 Xanthopurpurin 518-83-2 Xanthopurpurin is a natural product isolated and purified from the roots of Rubia cordifolia, effectively inhibits rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells, and shows mainly strong inhibition of collagen-induced platelet aggregation.
CSN14690 Triptoquinone A 142950-86-5 Triptoquinone A, a natural product isolated and purified from the roots of Tripterygium wilfordii Hook.f.
CSN14690 Triptoquinone A 142950-86-5 Triptoquinone A, a natural product isolated and purified from the roots of Tripterygium wilfordii Hook.f.
CSN20034 Thymoquinone   490-91-5 Thymoquinone is a phytochemical compound that acts as an angiogenesis inhibitor. Thymoquinone possesses potential analgesic, anticonvulsant, and anticancer properties in vitro.
CSN12365 Shikonin   517-89-5 Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 M, its a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc..
CSN13928 Sennoside C 37271-16-2 Sennoside C is a natural product isolated and purified from the leaves of Cassia angustifolia.
CSN16471 Sennoside A   81-27-6 Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
CSN15180 Salvisyrianone 250691-57-7 Salvisyrianone is a natural product isolated and purified from the herbs of Salvia syriaca.
CSN15182 Rubioncolin C 132242-52-5 Rubioncolin C is a natural product isolated and purified from plants.
CSN15308 Rubianthraquinone 644967-44-2 Rubianthraquinone is a natural product isolated and purified from the roots of Rubia yunnanensis.
CSN17087 Rubiadin 117-02-2 Rubiadin, a natural product isolated and purified from the roots of Rubia cordifolia with hepatoprotective effects against carbon tetrachloride (CCl 4 )-induced hepatic damage in rats and potent antioxidant property, can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner, and decrease bone loss through the inhibition of osteoclast formation, differentiation and bone resorption.
CSN19356 Rhein     478-43-3 Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.
CSN19889 Purpurin   81-54-9 Purpurin, a natural product isolated and purified from the herbs of Rubia cordifolia L. with antifungal activity, suppresses C. albicans morphogenesis and causes distorted biofilm formation, and is a specific inhibitor of Adipocyte-derived leucine aminopeptidase and could be developed as an anti-angiogenic agent.
CSN13528 Physcion 8-O-beta-D-Monoglucoside 23451-01-6 Physcion 8-O-beta-d-monoglucoside is a natural product.
CSN13997 Phyllostine 27270-89-9 Phyllostine, a natural product isolated and purified from Pencillium urticae, appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these metabolites.
CSN13536 Obtusin 70588-05-5 Obtusin is a natural product isolated and purified from Semen Cassiae.
CSN20571 Menaquinone-7 2124-57-4 Menaquinone-7 is a long-chain menaquinone member of Vitamin K2, showing anti-cancer activity.
CSN20565 Menaquinone-4 863-61-6 Menaquinone-4 is the most important member of short-chain menaquinones in Vitamine K2.
CSN11340 Lucidin 478-08-0 Lucidin is a natural component of Rubia tinctorum L.
CSN11267 Lapachol   84-79-7 Lapachol is a naturally occuring phenolic compound isolated from the bark of the lapacho tree, with anti-inflammatory, analgesic and antibiotic properties.
CSN19714 Juglone 481-39-0 Juglone significantly inhibits the proliferation and induce the apoptosis of SiHa cells and Caski cells, stimulates suicidal erythrocyte death or eryptosis at least in part by upregulation of ceramide abundance, energy depletion and activation of PKC, and prevents high-fat diet-induced liver injury and nerve inflammation in mice through inhibition of inflammatory cytokine secretion, NF-kappa B activation and endotoxin production. Its a natural product isolated and purified from the barks of Juglans regia L..
CSN15179 Isodiospyrin 20175-84-2 Isodiospyrin, a natural product isolated and purified from the herbs of Diospyros morrisiana, exhibits remarkably good antifungal activity, the MIC values of the isodiospyrin was 5-160 μg/mL & the MFC values was 40-160 μg/mL.
CSN20203 Hypocrellin B 123940-54-5 Hypocrellin B, a natural product isolated and purified from Hypocrella bambusae, has sonodynamic action to induce mitochondrial damage, survival inhibition, apoptosis and inhibit adhesion and migration of cancer cells.
CSN11182 Hypocrellin A 77029-83-5 Hypocrellin A is a natural product isolated and purified from the Hypocrella bambusae, with light-induced antitumor, antifungal and antiviral activities, showing photodynamic activity towards microorganisms.
CSN12612 Hypericin 548-04-9 Hypericin, a natural product isolated and purified from the herb of Hypericum perforatum L., is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum.
CSN13964 Aurantio-Obtusin 67979-25-3 GlucoAurantio-obtusin, a natural product isolated and purified from the seeds of Cassia obtusifolia L., possesses hypotensive and hypolipidemic effects.
CSN15029 Floribundone 1 118555-84-3 Floribundone 1 is a natural product isolated and purified from the herbs of Senna septemtrionalis.
CSN13340 Ethyl(1-Hydroxy-4-Oxocyclohexa-2,5-Dien-1-Yl)acetate 60263-06-1 Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate is a natural product isolated and purified from the herbs of Senecio scandens.
CSN10903 Embelin   550-24-3 Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 M in a cell-free assay.
CSN16710 Diacerein     13739-02-1 Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes.
CSN14072 Dehydro-alpha-Lapachone 15297-92-4 Dehydro-alpha-lapachone, a natural product isolated and purified from the roots of Radermachera sinica with antifungal, antibacterial and antitumor activities, can be as a potential drug for reducing cancer metastasis and can inhibit vessel regeneration, interfere with vessel anastomosis, and limit plexus formation in zebrafish.
CSN10741 Damnacanthal 477-84-9 Damnacanthal, a natural product isolated and purified from the fruit of Morinda citrifolia Linn., possesses anti-cancer property and can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGFc-Met axis.
CSN14045 Citreorosein 481-73-2 Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
CSN14045 Citreorosein 481-73-2 Citreorosein, a cAMP phosphodiesterase inhibitor isolated and purified from the root and rhizome of Rheum palmatum L., has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation and subsequent inhibition of transcription factor NF-κB activation.
CSN14572 Chrysophanol 8-O-Glucoside 13241-28-6 Chrysophanol 8-O-glucoside, a natural product isolated and purified from the roots of Rheum with potent inhibitory effect on collagen- and thrombin-induced platelet aggregation, only inhibits platelet phosphatidylserine exposure, but not exerts direct inhibition on intrinsic factors, suggests that it may be of therapeutic benefit for the prevention of platelet-related cardiovascular diseases.
CSN13535 Chrysoobtusin 70588-06-6 Chrysoobtusin is a natural product isolated and purified from Semen Cassiae.
CSN20328 Chlorobenzoyl Mansonone G N/A Chlorobenzoyl mansonone G, a derivative of mansonone G isolated from Mansonia gagei heartwoods, may have beneficial applications in the control of obesity through the suppression of PPAR-induced adipocyte differentiation and lipid accumulation.
CSN13601 beta,beta-Dimethylacrylalkannin 34539-65-6 beta,beta-Dimethylacrylalkannin, a natural product isolated and purified from the roots of Lithospermum erythrorhizon with radical scavenging activity, can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin, shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or stronger than the other compounds and positive control CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM and it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value, and exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 μMol·L-1.
CSN10252 Aloin B 28371-16-6 Aloin B is one isomer of aloin, which is a physiologically active anthraquinone present in aloe.
CSN11403 Aloin A   1415-73-2 Aloin A, an anthracycline from aloe plants, can be used as a chemopreventive factor with antineoplastic activity. It exhibits inhibition of phosphodiesterase and tyrosinase.
CSN17350 Aloe-Emodine   481-72-1 Aloe-emodin, a natural product isolated and purified from the root of Rheum palmatum L. with a specific in vitro and in vivo anti-neuroectodermal tumor activity, reduces the toxicity and ROS induced by both monomeric and oligomeric A species, appears to have some protective effect not only against hepatocyte death but also on the inflammatory response subsequent to lipid peroxidation and has a strong non-carcinogenic stimulant-laxative action when applied to the skin, although it may increase the carcinogenicity of some kind of radiation.
CSN12448 Acetyl Shikonin 24502-78-1 Acetyl shikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc., inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated, and is a non-selective cytochrome P450 inhibitor.
CSN13010 9-Hydroxy-alpha-Lapachone 22333-58-0 9-Hydroxy-alpha-lapachone, a natural product isolated and purified from the herbs of Catalpa ovata, exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 mM.
CSN14687 2-Methoxystypandrone 85122-21-0 2-Methoxystypandrone, a natural product isolated and purified from the roots of Polygonum cuspidatum, displays an immunomodulatory effect in a cellular model, specifically inhibits JAK and IKKβ kinase activities, blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity, concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins, and has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption.
CSN14925 2-CarbaMoyl-3-Hydroxy-1,4-Naphthoquinone 103646-20-4 2-CarbaMoyl-3-hydroxy-1,4-naphthoquinone is a natural product isolated and purified from plants.
CSN13009 2,6-Dimethoxy-1-Acetonylquinol 2215-96-5 2,6-Dimethoxy-1-acetonylquinol, a natural product isolated and purified from the barks of Ailanthus altissima, shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum and is devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line.
CSN18689 2,6-Dimethoxy-1,4-Benzoquinone   530-55-2 2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ugmL, and MBC values of 7.8, 7.8, and 31.2 ugmL respectively. It also produces genotoxic effects in patients taking dimethophrine, its a natural product isolated and purified from the barks of Liriodendron tulipifera.
CSN15309 1-O-Methylnataloe-Emodin 103392-51-4 1-O-Methylnataloe-emodin is a natural product isolated and purified from plants.
CSN15307 1,5,15-Tri-O-Methylmorindol 942609-65-6 1,5,15-Tri-O-methylmorindol, a natural product isolated and purified from the herbs of Morinda citrifolia, has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA.
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