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PTK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN25326 | Tyrphostin AG1433 | 168835-90-3 | Tyrphostin AG1433 is a tyrosine kinases inhibitor and also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50s of 5.0 μM and 9.3 μM, respectively. |
| CSN24162 | ST271 | 106392-48-7 | ST271 is a potent inhibitor of protein tyrosine kinase (PTK), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC50s of 6.7 and 9 μM, respectively. |
| CSN25272 | RG13022 | 136831-48-6 | RG-13022 significantly inhibited EGF-stimulated autophosphorylation of its receptor in two breast cancer cell lines that have abundant, although not amplified, EGF receptor content (MDA-231 and T47D).RG-13022 suppressed not only EGF-stimulated cancer cell proliferation in vitro but also tumor growth in nude mice. RG-13022 also increased the life span of these tumor-bearing nude mice. |
| CSN27382 | CZC-8004 | 916603-07-1 | CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase. |
| CSN23887 | BI-4464 | 1227948-02-8 | BI-4464 is a ATP competitive inhibitor of focal adhesion tyrosine kinase (PTK2/FAK) with IC50 of 17 nM. |
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