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Proteasome
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN25332 | 3,5-Bis(3,4-dichlorobenzylidene)piperidin-4-one | 145888-79-5 | PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor. It inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites, with anticancer activity. |
| CSN11436 | MG-132 | 133407-82-6 | MG-132 is an inhibitor of proteasome IC50 100 nM and calpain IC50 12 nM |
| CSN22376 | Clasto-Lactacystin β-lactone | 154226-60-5 | Clasto-Lactacystin -lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces, acts as an irreversible 20S proteasome inhibitor. |
| CSN14664 | Broussonin B | 73731-86-9 | Broussonin B, a natural product isolated and purified from the branch of Broussonetia papyrifera, induces neurite outgrowth in PC-12 cells at concentration of 50 mgmL and shows moderate inhibitory activities against a chymotrypsin-like activity of the proteasome. |
| CSN10115 | Bortezomib | 179324-69-7 | Bortezomib is an inhibitor of 20S proteasome with Ki of 0.6 nM. |
| CSN20399 | Aclarubicin HCl | 75443-99-1 | Aclarubicin HCl is the HCl salt of aclarubicin, an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. |
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