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Proteasome

Proteasome

Cat. No. Product Name CAS No. Information
CSN25332 3,5-Bis(3,4-dichlorobenzylidene)piperidin-4-one 145888-79-5 PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor. It inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites, with anticancer activity.
CSN11436 MG-132 133407-82-6 MG-132 is an inhibitor of proteasome IC50 100 nM and calpain IC50 12 nM
CSN22376 Clasto-Lactacystin β-lactone 154226-60-5 Clasto-Lactacystin -lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces, acts as an irreversible 20S proteasome inhibitor.
CSN14664 Broussonin B 73731-86-9 Broussonin B, a natural product isolated and purified from the branch of Broussonetia papyrifera, induces neurite outgrowth in PC-12 cells at concentration of 50 mgmL and shows moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.
CSN10115 Bortezomib 179324-69-7 Bortezomib is an inhibitor of 20S proteasome with Ki of 0.6 nM.
CSN20399 Aclarubicin HCl 75443-99-1 Aclarubicin HCl is the HCl salt of aclarubicin, an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus.
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