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Prostaglandin Receptor
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN17319 | Treprostinil sodium | 289480-64-4 | Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.60.1 and 6.21.2 nM, respectively. |
| CSN21858 | Tiaprost | 71116-82-0 | Tiaprost is a prostaglandin F2 alpha analogue as an estrus-synchronizing agent. |
| CSN24068 | TG4-155 | 1164462-05-8 | TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist. |
| CSN21854 | Terbogrel | 149979-74-8 | Terbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor with both IC50s of about 10 nM. |
| CSN22249 | Taprenepag isopropyl | 1005549-94-9 | Taprenepag isopropyl is a highly selective EP2 receptor agonist. |
| CSN12962 | Tafluprost | 209860-87-7 | Tafluprost is an anti-glaucoma prostaglandin (PG) analog. |
| CSN16883 | Setipiprant | 866460-33-5 | Setipiprant is an orally available, selective CRTH2 antagonist. |
| CSN21394 | RO1138452 | 221529-58-4 | RO1138452 is a selective antagonist of prostacyclin (IP) receptor with pKi of 9.3 0.1 in human platelets. |
| CSN19400 | Ramatroban | 116649-85-5 | Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. |
| CSN19825 | Ralinepag | 1187856-49-0 | Ralinepag, is an orally available agonist of the prostacyclin (IP) receptor. |
| CSN23451 | p-Hydroxycinnamic acid | 7400-08-0 | p-Hydroxy-cinnamic acid is the isomer of cinnamic acid with anti-mutagenic and anti-tumor activities. |
| CSN25724 | ONO-8130 | 459841-96-4 | ONO 8130 is an antagonist of EP1 receptor. |
| CSN16825 | Selexipag | 475086-01-2 | NS-304 is an agonist of prostacyclin IP1 receptor with Ki of 260 nM. It is used for the treatment of pulmonary arterial hypertension. |
| CSN11531 | Nedocromil | 69049-73-6 | Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. |
| CSN17385 | MK-2894 sodium salt | 1006036-88-9 | MK-2894 sodium is a highly potent and selective second generation EP4 antagonist. |
| CSN17384 | MK-2894 | 1006036-87-8 | MK-2894 is a highly potent and selective second generation EP4 antagonist. |
| CSN11301 | Limaprost | 74397-12-9 | Limaprost is a PGE1 analog and potent platelet adhesion inhibitor. |
| CSN18339 | Laropiprant | 571170-77-9 | Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM and exhibits 1,000 fold selectivity over DP2 receptor (Ki0.75 M). |
| CSN25731 | L-161982 | 147776-06-5 | L-161,982 is a potent EP4 receptor antagonist with Ki value of 0.024 μM. |
| CSN18274 | GW627368 | 439288-66-1 | GW627368 is a potent and selective competitive antagonist of prostanoid EP4 receptor (Ki 100 nM) with additional human TP receptor affinity (Ki 150 nM). |
| CSN18265 | Grapiprant | 415903-37-6 | Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). |
| CSN18130 | Evatanepag | 223488-57-1 | Evatanepag is an EP2 receptor selective prostaglandin E2 PGE2 agonist that induces local bone formation with EC50 of 03 nM |
| CSN20029 | Esuberaprost Sodium | 88475-69-8 | Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH). |
| CSN20026 | Esuberaprost | 94132-88-4 | Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH). |
| CSN26370 | Epoprostenol sodium | 61849-14-7 | Epoprostenol sodium, a potent agonist at IP prostanoid receptors, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH)[1]. Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation[2]. |
| CSN11793 | Dinoprost tromethamine salt | 38562-01-5 | Dinoprost tromethamine is a natural prostaglandin used as an abortifacient. |
| CSN11792 | Dinoprost | 551-11-1 | Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
| CSN25728 | DG-041 | 861238-35-9 | DG-041 is a potent and selective antagonist of prostanoid EP3 receptor with IC50 of 4.6 nM. |
| CSN21985 | Decursinol angelate | 130848-06-5 | Decursinol angelate (DA) blocks PGE2-induced activation of the EP2 receptor signaling pathway, including the activation of PKA and the phosphorylation of CREB. |
| CSN26495 | CRTh2 antagonist 2 | 780763-95-3 | CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia[1]. |
| CSN25453 | Cloprostenol sodium salt | 55028-72-3 | Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist. |
| CSN26158 | Sodium (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate | 62561-03-9 | Cloprostenol is a PGF2 α analogue, working as an FP receptor agonist. |
| CSN13150 | CJ-42794 | 847728-01-2 | CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits 3H-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). |
| CSN22111 | Carbacyclin | 69552-46-1 | Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. |
| CSN21535 | BW 245C | 72814-32-5 | BW 245C is a selective agonist for the DP1 receptor. |
| CSN17217 | Bimatoprost | 155206-00-1 | Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension. |
| CSN25356 | Asapiprant | 932372-01-5 | Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM. |
| CSN21466 | Aligeron | 70713-45-0 | Aligeron is a non-selective antagonist of prostaglandin (PG) with vasodilatory properties. |
| CSN17196 | AH 6809 | 33458-93-4 | AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. |
| CSN25755 | (+)-Fluprostenol | 54276-17-4 | (+)-Fluprostenol is an agonist of prostaglandin F2α (FP) receptor with Ki of 49.9 nM and EC50 of 2.4 nM. |
| CSN42950 | GSK-269984A | 892664-04-9 |
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