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Prostaglandin Receptor

Prostaglandin Receptor

Cat. No. Product Name CAS No. Information
CSN17319 Treprostinil Sodium 289480-64-4 Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.60.1 and 6.21.2 nM, respectively.
CSN21858 Tiaprost 71116-82-0 Tiaprost is a prostaglandin F2 alpha analogue as an estrus-synchronizing agent.
CSN24068 TG4-155 1164462-05-8 TG4-155 is a brain penetrant prostaglandin EP2 specific antagonist.
CSN21854 Terbogrel 149979-74-8 Terbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor with both IC50s of about 10 nM.
CSN22249 Taprenepag Isopropyl 1005549-94-9 Taprenepag isopropyl is a highly selective EP2 receptor agonist.
CSN16883 Setipiprant 866460-33-5 Setipiprant is an orally available, selective CRTH2 antagonist.
CSN25726 SC 51089 146033-02-5 SC-51089, also known as CID132748, is an antagonist of PGE2 and selective for the EP1 receptor subtype with antinociceptive activity.
CSN25725 SC 51322 146032-79-3 SC 51322 is an antagonist of EP1 prostanoid receptor with Ki of 13.8 nM.
CSN25727 SC 19220 19395-87-0 SC 19220 is a competitive antagonist of EP1 receptor.
CSN23716 Rumodolin 81846-19-7 Rumodolinl, a analog of prostacyclin, is an agonist of IP receptor that used clinically to treat pulmonary arterial hypertension. It is a vasodilator with antithrombotic and anti-inflammatory properties.
CSN21394 RO1138452 221529-58-4 RO1138452 is a selective antagonist of prostacyclin (IP) receptor with pKi of 9.3 0.1 in human platelets.
CSN19400 Ramatroban   116649-85-5 Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.
CSN19825 Ralinepag 1187856-49-0 Ralinepag, is an orally available agonist of the prostacyclin (IP) receptor.
CSN20322 Prostaglandin D2 41598-07-6 Prostaglandin D2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis
CSN24172 Latanoprostene bunod 860005-21-6 PF-3187207 is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity.
CSN23451 p-Hydroxy-Cinnamic Acid   7400-08-0 p-Hydroxy-cinnamic acid is the isomer of cinnamic acid with anti-mutagenic and anti-tumor activities.
CSN25724 ONO 8130 459841-96-4 ONO 8130 is an antagonist of EP1 receptor.
CSN22473 OBE022 2005486-31-5 OBE022 is an oral and selective prostaglandin F2 PGF2 receptor antagonist with Kis of 1 nM 26 nM for human and rat FP receptors respectively
CSN16825 NS-304   475086-01-2 NS-304 is an agonist of prostacyclin IP1 receptor with Ki of 260 nM. It is used for the treatment of pulmonary arterial hypertension.
CSN11531 Nedocromil 69049-73-6 Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
CSN17385 MK-2894 Sodium 1006036-88-9 MK-2894 sodium is a highly potent and selective second generation EP4 antagonist.
CSN17384 MK-2894 1006036-87-8 MK-2894 is a highly potent and selective second generation EP4 antagonist.
CSN11301 Limaprost 74397-12-9 Limaprost is a PGE1 analog and potent platelet adhesion inhibitor.
CSN18339 Laropiprant 571170-77-9 Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM and exhibits 1,000 fold selectivity over DP2 receptor (Ki0.75 M).
CSN25731 L-161,982 147776-06-5 L-161,982 is a potent EP4 receptor antagonist with Ki value of 0.024 μM.
CSN22113 Ifetroban 143443-90-7 Ifetroban is a long-acting thromboxane A2 receptor antagonist with antiplatelet activity
CSN18274 GW627368 439288-66-1 GW627368 is a potent and selective competitive antagonist of prostanoid EP4 receptor (Ki 100 nM) with additional human TP receptor affinity (Ki 150 nM).
CSN18265 Grapiprant 415903-37-6 Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).
CSN10940 Ethamsylate   2624-44-4 Ethamsylate acts as a haemostatic drug by increasing capillary endothelial resistance and promoting platelet adhesion
CSN20029 Esuberaprost Sodium 88475-69-8 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN20026 Esuberaprost 94132-88-4 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN10910 Enprostil 73121-56-9 Enprostil is a synthetic prostaglandin designed to resemble dinoprostone
CSN11793 Dinoprost Tromethamine 38562-01-5 Dinoprost tromethamine is a natural prostaglandin used as an abortifacient.
CSN11792 Dinoprost 551-11-1 Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
CSN25728 DG 041 861238-35-9 DG-041 is a potent and selective antagonist of prostanoid EP3 receptor with IC50 of 4.6 nM.
CSN21985 Decursinol angelate 130848-06-5 Decursinol angelate (DA) blocks PGE2-induced activation of the EP2 receptor signaling pathway, including the activation of PKA and the phosphorylation of CREB.
CSN25453 Cloprostenol Sodium Salt 55028-72-3 Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
CSN26158 (+)-Cloprostenol (sodium salt) 62561-03-9 Cloprostenol is a PGF2 α analogue, working as an FP receptor agonist.
CSN13150 CJ-42794 847728-01-2 CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits 3H-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3).
CSN22111 Carbacyclin 69552-46-1 Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation.
CSN21535 BW245C 72814-32-5 BW 245C is a selective agonist for the DP1 receptor.
CSN17217 Bimatoprost 155206-00-1 Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.
CSN25730 BGC 20-1531 HCl 1962928-26-2 BGC 20-1531 hydrochloride is a selective antagonist of EP4 with Ki of 3 nM.
CSN25356 Asapiprant 932372-01-5 Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM.
CSN19378 Alprostadil 745-65-3 Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction
CSN21466 Aligeron 70713-45-0 Aligeron is a non-selective antagonist of prostaglandin (PG) with vasodilatory properties.  
CSN17196 AH 6809 33458-93-4 AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors.
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