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Prostaglandin Receptor

Prostaglandin Receptor

Cat. No. Product Name CAS No. Information
CSN17319 Treprostinil Sodium 289480-64-4 Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.60.1 and 6.21.2 nM, respectively.
CSN21858 Tiaprost 71116-82-0 Tiaprost is a prostaglandin F2 alpha analogue as an estrus-synchronizing agent.
CSN21854 Terbogrel 149979-74-8 Terbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor with both IC50s of about 10 nM.
CSN23716 Rumodolin 81846-19-7 Rumodolinl, a analog of prostacyclin, is an agonist of IP receptor that used clinically to treat pulmonary arterial hypertension. It is a vasodilator with antithrombotic and anti-inflammatory properties.
CSN21394 RO1138452 221529-58-4 RO1138452 is a selective antagonist of prostacyclin (IP) receptor with pKi of 9.3 0.1 in human platelets.
CSN19400 Ramatroban   116649-85-5 Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.
CSN19825 Ralinepag 1187856-49-0 Ralinepag, is an orally available agonist of the prostacyclin (IP) receptor.
CSN20322 Prostaglandin D2 41598-07-6 Prostaglandin D2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis
CSN23451 p-Hydroxy-Cinnamic Acid   7400-08-0 p-Hydroxy-cinnamic acid is the isomer of cinnamic acid with anti-mutagenic and anti-tumor activities.
CSN11531 Nedocromil 69049-73-6 Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
CSN11301 Limaprost 74397-12-9 Limaprost is a PGE1 analog and potent platelet adhesion inhibitor.
CSN20466 L-798,106 244101-02-8 L-798106 is a potent and highly selective prostanoid EP3 receptor antagonist Ki values are 03 916 5000 and 5000 nM at EP3 EP4 EP1 and EP2 respectively and it can attenuate sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo
CSN25731 L-161,982 147776-06-5 L-161,982 is a potent EP4 receptor antagonist with Ki value of 0.024 μM.
CSN22113 Ifetroban 143443-90-7 Ifetroban is a long-acting thromboxane A2 receptor antagonist with antiplatelet activity
CSN18274 GW627368 439288-66-1 GW627368 is a potent and selective competitive antagonist of prostanoid EP4 receptor (Ki 100 nM) with additional human TP receptor affinity (Ki 150 nM).
CSN18265 Grapiprant 415903-37-6 Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).
CSN18130 Evatanepag 223488-57-1 Evatanepag is an EP2 receptor selective prostaglandin E2 PGE2 agonist that induces local bone formation with EC50 of 03 nM
CSN20029 Esuberaprost Sodium 88475-69-8 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN20026 Esuberaprost 94132-88-4 Esuberaprost is a potential substance for treating pulmonary arterial hypertension (PAH).
CSN11793 Dinoprost Tromethamine 38562-01-5 Dinoprost tromethamine is a natural prostaglandin used as an abortifacient.
CSN11792 Dinoprost 551-11-1 Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
CSN21985 Decursinol angelate 130848-06-5 Decursinol angelate (DA) blocks PGE2-induced activation of the EP2 receptor signaling pathway, including the activation of PKA and the phosphorylation of CREB.
CSN26158 (+)-Cloprostenol (sodium salt) 62561-03-9 Cloprostenol is a PGF2 α analogue, working as an FP receptor agonist.
CSN21535 BW245C 72814-32-5 BW 245C is a selective agonist for the DP1 receptor.
CSN17217 Bimatoprost 155206-00-1 Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.
CSN19378 Alprostadil 745-65-3 Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction
CSN21466 Aligeron 70713-45-0 Aligeron is a non-selective antagonist of prostaglandin (PG) with vasodilatory properties.  
CSN17196 AH 6809 33458-93-4 AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors.
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