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CAS No.: 1025065-69-3

SGI-1776 Catalog No. CSN17161

Synonyms: SGI-1776 Free Base

SGI-1776 free base is an ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay 50- and 10-fold selective versus Pim2 and Pim3 also potent to Flt3 and haspin

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Biological Activity

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Technical Information

CAS No. 1025065-69-3 Storage
Formula C20H22F3N5O Shipping Blue ice
M.W. 405.42 Synonyms SGI-1776 Free Base
Solubility
DMSO500 mg/mL (1233.3 mM) warming
Waterinsoluble
Formulation
IP2% DMSO+2% Tween80+40% PEG300+water8 mg/mLclear
PO0.5% CMC-Na19 mg/mLsuspension

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