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PPAR
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12217 | Wy-14643 | 50892-23-4 | Wy-14643 is an agonist of PPAR with EC50 of 0.63 M that can decrease the inflammatory response. It has other functions including lipid metabolism, cell proliferation, differentiation, adipogenesis etc.. |
| CSN12155 | Troglitazone | 97322-87-7 | Troglitazone is a PPAR agonist with EC50 of 780 nM in murine and 555 nM in human It has no activity at PPAR or PPAR and can act as an anti-diabetic agent |
| CSN18774 | T0070907 | 313516-66-4 | T0070907 is an antagonist of PPAR with IC50 of 1 nM |
| CSN20285 | Suksdorfin | 53023-17-9 | Suksdorfin promotes adipocyte differentiation and improves abnormalities in glucose metabolism via PPAR activation |
| CSN20554 | Seladelpar | 851528-79-5 | Seladelpar is selectively exhibits activation of peroxisome proliferator-activated receptor (PPAR) which may has therapeutic activity against dyslipidemia, metabolic syndrome, type 2 diabetes, and non-alcoholic steatohepatitis. |
| CSN16902 | Saroglitazar | 495399-09-2 | Saroglitazar is a peroxisome proliferator-activated receptor PPAR agonist with predominant PPAR and moderate PPAR activity withEC50values of 065 pM and 3 nM in HepG2 cells respectively |
| CSN12570 | Rosiglitazone Maleate | 155141-29-0 | Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR) with Kd of 40 nM and it also acts as a modulator of TRP channels. |
| CSN12512 | Rosiglitazone | 122320-73-4 | Rosiglitazone is a selective agonist of PPAR with EC50 of 60 nM and has no effect on PPAR and PPAR It is an insulin sensitizing and potent antihyperglycemic agent |
| CSN10123 | Rosiglitazone HCl | 302543-62-0 | Rosiglitazone hydrochloride is a blood glucose-lowering drug stimulating insulin secretion by binding to the PPAR receptors in fat cells |
| CSN22489 | Pparδ Agonist | 942594-93-6 | PPAR agonist is a PPAR agonist extracted from patent US20180071304 compound example 10 |
| CSN22490 | Pparδ Agonist 1 | 1902161-12-9 | Ppar agonist 1 is a PPAR- agonist with an EC50 of 506 nM used in the research of PPAR-delta related diseases such as mitochondrial diseases muscular diseases vascular diseases demyelinating diseases and metabolic diseases |
| CSN10029 | Pioglitazone | 111025-46-8 | Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPAR, EC50 500-600 nM) over PPAR. It also a thiazolidinedione (TZD) anti-diabetic. |
| CSN12489 | Pioglitazone HCl | 112529-15-4 | Pioglitazone hydrochloride is a selective agonist of PPAR with EC50 of 0.93 M which is used to treat diabetes. |
| CSN18945 | Pemafibrate | 848259-27-8 | Pemafibrateis a selective PPAR modulator SPPARM that has antihyperlipidaemic activity |
| CSN18946 | Pemafibrate Racemate | 848258-31-1 | Pemafibrate racemate is a selective PPAR modulator SPPARM |
| CSN11647 | Palmitoylethanolamide | 544-31-0 | Palmitoylethanolamide endogenous fatty acid amide is an agonist of PPAR- in vitro with an EC50 value of 31 04 M It can be used for preventing the infection of virus |
| CSN20649 | Oleoylethanolamide | 111-58-0 | Oleoylethanolamide is a lipid mediator and analog of anandamide that is involved in peripheral regulation of feeding It is also a selective GPR55 agonist EC50 values are 044 30 and 30 M at GPR55 CB1 and CB2 respectively and PPAR agonist EC50 120 nM |
| CSN20225 | MHY553 | 6265-56-1 | MHY553 a PPAR agonist alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging |
| CSN11258 | L-165,041 | 79558-09-1 | L-165041 is a cell permeable PPAR agonist which induces adipocyte differentiation in NIH-PPAR cells |
| CSN20539 | IVA-337 | 927961-18-0 | IVA-337 is a agonist of peroxisome proliferator-activated receptors PPAR which is widely used in the study of lung fibrosis and pulmonary hypertension |
| CSN11131 | GW9662 | 22978-25-2 | GW9662 selectively antagonizes PPAR with IC50 of 3.3 nM. It can inhibit the growth of mammary cancer cells. |
| CSN11130 | GW1929 | 196808-24-9 | GW1929 is a synthetic peroxisome proliferator-activated receptor- (PPAR) agonist with IC50 of 6.2 nM and 13 nM for human and mouse PPAR, respectively. |
| CSN13142 | GW0742 | 317318-84-6 | GW0742 is an agonist of PPAR with EC50 of 11 nM It can protect right heart from hypertrophy and enhance lipid metabolism in heart |
| CSN22426 | GW 6471 | 880635-03-0 | GW 6471 is a potent PPAR antagonist |
| CSN15822 | GSK3787 | 188591-46-0 | GSK3787 selectively and irreversibly antagonizes PPAR with pIC50 of 66 with no significant effect on hPPAR or hPPAR |
| CSN15777 | GSK0660 | 1014691-61-2 | GSK0660 is a selective antagonist of PPAR and exhibits inverse agonist effects when used alone |
| CSN22403 | Fonadelpar | 515138-06-4 | Fonadelpar is a PPAR agonist, used in the research of neuroparalytic keratopathy. |
| CSN18750 | Fenofibric Acid | 42017-89-0 | Fenofibric acid is an agonist of PPAR that can regulate lipid level. It also exhibits inhibition of COX-2. |
| CSN12680 | Fenofibrate | 49562-28-9 | Fenofibrate is an agonist of PPAR EC50 30 M and an inhibitor of CYP2C19 IC50 02 M and CYP2B6 IC50 07 M Fenofibrate is a fibric acid derivative and used to treat hypercholesterolemia and hypertriglyceridemia |
| CSN13948 | Eupatilin | 22368-21-4 | Eupatilin is an activiator of PPAR It is a lipohilic flavonoid extracted from artemisia species with antioxidant anti-tumor and anti-inflammatory activities |
| CSN16153 | Elafibranor | 923978-27-2 | Elafibranor is an agonist of PPAR and PPAR with EC50 values of 45 nM and 175 nM respectively Elafibranor also attenuates nonalcoholic steatohepatitis without fibrosis worsening |
| CSN17750 | DG172 2HCl | 1361504-77-9 | DG172 dihydrochloride is a PPAR-selective ligand showing high binding affinity IC50 27 nM and potent inverse agonistic properties |
| CSN13070 | Clofibric Acid | 882-09-7 | Clofibric acid is an agonist of PPAR and can act as a hypolipidemic agent |
| CSN11481 | Clofibrate | 637-07-0 | Clofibrate a fibric acid derivative is a selective agonist of peroxisome proliferator-activated receptor PPAR with EC50 of 50 M Clofibrate has been used to treat hyperlipoproteinemia type III and severe hypertriglyceridemia |
| CSN10653 | Ciprofibrate | 52214-84-3 | Ciprofibrate is an agonist of peroxisome proliferator-activated receptor PPAR It is used in dyslipidaemia |
| CSN18278 | CDDO-Im | 443104-02-7 | CDDO-Im is a synthetic triterpenoid more potent than its parent compound CDDO both in vitro and in vivo and a PPAR agonist. |
| CSN17378 | BMS-687453 | 1000998-59-3 | BMS-687453 is a potent and selective PPAR agonist with an EC50 of 10 nM for human PPAR and 410-fold selectivity vs human PPAR in PPAR-GAL4 transactivation assays |
| CSN10445 | Bezafibrate | 41859-67-0 | Bezafibrate is the agonist of PPAR and the EC50 for PPAR PPAR PPAR is 50 20 and 60 nM respectively It has hypolipidemic effect |
| CSN18081 | Balaglitazone | 199113-98-9 | Balaglitazone is a partial agonist of PPAR-. |
| CSN14141 | Arjunolic Acid | 465-00-9 | Arjunolic acid a natural peroxisome proliferator-activated receptor alpha agonist isolated and purified from the fruits of Terminalia chebula Retz can protect against cisplatin-induced testicular injury by attenuating oxidative stress parameters along with downregulation of iNOS TNF- and p38-MAPK testicular expressions |
| CSN20181 | AMG-131 | 315224-26-1 | AMG-131 is a hypoglycemic agent It is a potent PPAR partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs |
| CSN10234 | Aleglitazar | 475479-34-6 | Aleglitazar is a dual PPAR- agonist with IC50 of 2.8 nM4.6 nM. |
| CSN12767 | 4-(4-Hydroxyphenyl)-2-Butanone | 5471-51-2 | 4-4-Hydroxyphenyl-2-butanone is the primary aroma compound of red raspberries and shows PPAR- agonistic activity |
| CSN22773 | CP 775146 | 702680-17-9 | |
| CSN22845 | GW 1929 HCl | 1217466-21-1 | |
| CSN22759 | Ciglitazone | 74772-77-3 | |
| CSN22800 | Edaglitazone | 213411-83-7 | |
| CSN22706 | BADGE | 1675-54-3 | |
| CSN23086 | S26948 | 353280-43-0 | |
| CSN23127 | SR 202 | 76541-72-5 |
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