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PPAR

PPAR

Cat. No. Product Name CAS No. Information
CSN12217 Wy-14643 50892-23-4 Wy-14643 is an agonist of PPAR with EC50 of 0.63 M that can decrease the inflammatory response. It has other functions including lipid metabolism, cell proliferation, differentiation, adipogenesis etc..
CSN12155 Troglitazone 97322-87-7 Troglitazone is a PPAR agonist with EC50 of 780 nM in murine and 555 nM in human It has no activity at PPAR or PPAR and can act as an anti-diabetic agent
CSN18774 T0070907   313516-66-4 T0070907 is an antagonist of PPAR with IC50 of 1 nM
CSN20285 Suksdorfin 53023-17-9 Suksdorfin promotes adipocyte differentiation and improves abnormalities in glucose metabolism via PPAR activation
CSN20554 Seladelpar   851528-79-5 Seladelpar is selectively exhibits activation of peroxisome proliferator-activated receptor (PPAR) which may has therapeutic activity against dyslipidemia, metabolic syndrome, type 2 diabetes, and non-alcoholic steatohepatitis.
CSN16902 Saroglitazar 495399-09-2 Saroglitazar is a peroxisome proliferator-activated receptor PPAR agonist with predominant PPAR and moderate PPAR activity withEC50values of 065 pM and 3 nM in HepG2 cells respectively
CSN12570 Rosiglitazone Maleate   155141-29-0 Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR) with Kd of 40 nM and it also acts as a modulator of TRP channels.
CSN12512 Rosiglitazone     122320-73-4 Rosiglitazone is a selective agonist of PPAR with EC50 of 60 nM and has no effect on PPAR and PPAR It is an insulin sensitizing and potent antihyperglycemic agent
CSN10123 Rosiglitazone HCl 302543-62-0 Rosiglitazone hydrochloride is a blood glucose-lowering drug stimulating insulin secretion by binding to the PPAR receptors in fat cells
CSN22489 Pparδ Agonist 942594-93-6 PPAR agonist is a PPAR agonist extracted from patent US20180071304 compound example 10
CSN22490 Pparδ Agonist 1 1902161-12-9 Ppar agonist 1 is a PPAR- agonist with an EC50 of 506 nM used in the research of PPAR-delta related diseases such as mitochondrial diseases muscular diseases vascular diseases demyelinating diseases and metabolic diseases
CSN10029 Pioglitazone   111025-46-8 Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPAR, EC50 500-600 nM) over PPAR. It also a thiazolidinedione (TZD) anti-diabetic.
CSN12489 Pioglitazone HCl   112529-15-4 Pioglitazone hydrochloride is a selective agonist of PPAR with EC50 of 0.93 M which is used to treat diabetes.
CSN18945 Pemafibrate 848259-27-8 Pemafibrateis a selective PPAR modulator SPPARM that has antihyperlipidaemic activity
CSN18946 Pemafibrate Racemate 848258-31-1 Pemafibrate racemate is a selective PPAR modulator SPPARM
CSN11647 Palmitoylethanolamide   544-31-0 Palmitoylethanolamide endogenous fatty acid amide is an agonist of PPAR- in vitro with an EC50 value of 31 04 M It can be used for preventing the infection of virus
CSN20649 Oleoylethanolamide 111-58-0 Oleoylethanolamide is a lipid mediator and analog of anandamide that is involved in peripheral regulation of feeding It is also a selective GPR55 agonist EC50 values are 044 30 and 30 M at GPR55 CB1 and CB2 respectively and PPAR agonist EC50 120 nM
CSN20225 MHY553 6265-56-1 MHY553 a PPAR agonist alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging
CSN11258 L-165,041 79558-09-1 L-165041 is a cell permeable PPAR agonist which induces adipocyte differentiation in NIH-PPAR cells
CSN20539 IVA-337   927961-18-0 IVA-337 is a agonist of peroxisome proliferator-activated receptors PPAR which is widely used in the study of lung fibrosis and pulmonary hypertension
CSN11131 GW9662 22978-25-2 GW9662 selectively antagonizes PPAR with IC50 of 3.3 nM. It can inhibit the growth of mammary cancer cells.
CSN11130 GW1929 196808-24-9 GW1929 is a synthetic peroxisome proliferator-activated receptor- (PPAR) agonist with IC50 of 6.2 nM and 13 nM for human and mouse PPAR, respectively.
CSN13142 GW0742   317318-84-6 GW0742 is an agonist of PPAR with EC50 of 11 nM It can protect right heart from hypertrophy and enhance lipid metabolism in heart
CSN22426 GW 6471 880635-03-0 GW 6471 is a potent PPAR antagonist
CSN15822 GSK3787   188591-46-0 GSK3787 selectively and irreversibly antagonizes PPAR with pIC50 of 66 with no significant effect on hPPAR or hPPAR
CSN15777 GSK0660 1014691-61-2 GSK0660 is a selective antagonist of PPAR and exhibits inverse agonist effects when used alone
CSN22403 Fonadelpar 515138-06-4 Fonadelpar is a PPAR agonist, used in the research of neuroparalytic keratopathy.
CSN18750 Fenofibric Acid   42017-89-0 Fenofibric acid is an agonist of PPAR that can regulate lipid level. It also exhibits inhibition of COX-2.
CSN12680 Fenofibrate   49562-28-9 Fenofibrate is an agonist of PPAR EC50 30 M and an inhibitor of CYP2C19 IC50 02 M and CYP2B6 IC50 07 M Fenofibrate is a fibric acid derivative and used to treat hypercholesterolemia and hypertriglyceridemia
CSN13948 Eupatilin   22368-21-4 Eupatilin is an activiator of PPAR It is a lipohilic flavonoid extracted from artemisia species with antioxidant anti-tumor and anti-inflammatory activities
CSN16153 Elafibranor 923978-27-2 Elafibranor is an agonist of PPAR and PPAR with EC50 values of 45 nM and 175 nM respectively Elafibranor also attenuates nonalcoholic steatohepatitis without fibrosis worsening
CSN17750 DG172 2HCl 1361504-77-9 DG172 dihydrochloride is a PPAR-selective ligand showing high binding affinity IC50 27 nM and potent inverse agonistic properties
CSN13070 Clofibric Acid   882-09-7 Clofibric acid is an agonist of PPAR and can act as a hypolipidemic agent
CSN11481 Clofibrate   637-07-0 Clofibrate a fibric acid derivative is a selective agonist of peroxisome proliferator-activated receptor PPAR with EC50 of 50 M Clofibrate has been used to treat hyperlipoproteinemia type III and severe hypertriglyceridemia
CSN10653 Ciprofibrate   52214-84-3 Ciprofibrate is an agonist of peroxisome proliferator-activated receptor PPAR It is used in dyslipidaemia
CSN18278 CDDO-Im 443104-02-7 CDDO-Im is a synthetic triterpenoid more potent than its parent compound CDDO both in vitro and in vivo and a PPAR agonist.
CSN17378 BMS-687453 1000998-59-3 BMS-687453 is a potent and selective PPAR agonist with an EC50 of 10 nM for human PPAR and 410-fold selectivity vs human PPAR in PPAR-GAL4 transactivation assays
CSN10445 Bezafibrate   41859-67-0 Bezafibrate is the agonist of PPAR and the EC50 for PPAR PPAR PPAR is 50 20 and 60 nM respectively It has hypolipidemic effect
CSN18081 Balaglitazone 199113-98-9 Balaglitazone is a partial agonist of PPAR-.
CSN14141 Arjunolic Acid 465-00-9 Arjunolic acid a natural peroxisome proliferator-activated receptor alpha agonist isolated and purified from the fruits of Terminalia chebula Retz can protect against cisplatin-induced testicular injury by attenuating oxidative stress parameters along with downregulation of iNOS TNF- and p38-MAPK testicular expressions
CSN20181 AMG-131 315224-26-1 AMG-131 is a hypoglycemic agent It is a potent PPAR partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs
CSN10234 Aleglitazar 475479-34-6 Aleglitazar is a dual PPAR- agonist with IC50 of 2.8 nM4.6 nM.
CSN12767 4-(4-Hydroxyphenyl)-2-Butanone   5471-51-2 4-4-Hydroxyphenyl-2-butanone is the primary aroma compound of red raspberries and shows PPAR- agonistic activity
CSN22773 CP 775146 702680-17-9
CSN22845 GW 1929 HCl 1217466-21-1
CSN22759 Ciglitazone 74772-77-3
CSN22800 Edaglitazone 213411-83-7
CSN22706 BADGE 1675-54-3
CSN23086 S26948 353280-43-0
CSN23127 SR 202 76541-72-5
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