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PPAR

PPAR

Cat. No. Product Name CAS No. Information
CSN12217 Wy-14643 50892-23-4 Wy-14643 is an agonist of PPAR with EC50 of 0.63 M that can decrease the inflammatory response. It has other functions including lipid metabolism, cell proliferation, differentiation, adipogenesis etc..
CSN20285 Suksdorfin 53023-17-9 Suksdorfin promotes adipocyte differentiation and improves abnormalities in glucose metabolism via PPAR activation
CSN23127 SR 202 76541-72-5 SR 202 is a selective PPARγ antagonist which attenuates troglitazone-induced PPARγ transcriptional activity with IC50 value of 140μM. It inhibits PPARγ-dependent adipocyte differentiation and growth in vitro and in vivo and improves insulin sensitivity in diabetic ob/ob mice and increases HDL levels in rats in vivo.
CSN12570 Rosiglitazone Maleate   155141-29-0 Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR) with Kd of 40 nM and it also acts as a modulator of TRP channels.
CSN12570 Rosiglitazone Maleate   155141-29-0 Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR) with Kd of 40 nM and it also acts as a modulator of TRP channels.
CSN10029 Pioglitazone   111025-46-8 Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPAR, EC50 500-600 nM) over PPAR. It also a thiazolidinedione (TZD) anti-diabetic.
CSN12489 Pioglitazone HCl   112529-15-4 Pioglitazone HCl is a selective agonist of PPARγ with EC50 of 0.93 μM which is used to treat diabetes.
CSN12489 Pioglitazone HCl   112529-15-4 Pioglitazone HCl is a selective agonist of PPARγ with EC50 of 0.93 μM which is used to treat diabetes.
CSN25412 Oroxin A 57396-78-8 Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence.
CSN13703 MK-886   118414-82-7 MK886 is an inhibitor of 5-lipoxygenase activating protein FLAP PPAR and the biosynthesis of leukotriene LT
CSN20225 MHY553 6265-56-1 MHY553 a PPAR agonist alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging
CSN21901 Imiglitazar 250601-04-8 Imiglitazar is a potent and dual human PPARα and PPARγ1 agonist with EC50 values of 67 and 31 nM, respectively.
CSN27564 Gypenoside XLIX 94987-08-3 Gypenoside XLIX, a dammarane-type glycoside, is a prominent component of G. pentaphyllum. Gypenoside XLIX is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator and inhibits cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) overexpression and hyperactivity in human endothelial cells.
CSN11131 GW9662   22978-25-2 GW9662 selectively antagonizes PPAR with IC50 of 3.3 nM. It can inhibit the growth of mammary cancer cells.
CSN11130 GW1929 196808-24-9 GW1929 is a synthetic peroxisome proliferator-activated receptor- (PPAR) agonist with IC50 of 6.2 nM and 13 nM for human and mouse PPAR, respectively.
CSN11100 Glabridin   59870-68-7 Glabridin has many biological functions such as regulating the synthesis and activity of iNOS under high-glucose levels, significantly inhibiting free radicals generated during metabolism in the body, and protecting against oxidation-sensitive biomacromolecules (LDL, LDL, DNA) and cell walls. It is a natural product isolated and purified from the roots of Glycyrrhiza glabra L. with whitening and anti-aging activity.
CSN18750 Fenofibric Acid   42017-89-0 Fenofibric acid is an agonist of PPAR that can regulate lipid level. It also exhibits inhibition of COX-2.
CSN25193 Cinnamyl alcohol 104-54-1 Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon.
CSN22759 Ciglitazone 74772-77-3 Ciglitazone is a selective agonist at PPARγ (peroxisome proliferator-activated receptor γ) with an EC50 of 3 μM in vitro.
CSN18278 CDDO-Im 443104-02-7 CDDO-Im is a synthetic triterpenoid more potent than its parent compound CDDO both in vitro and in vivo and a PPAR agonist.
CSN10449 Bilobetin 521-32-4 Bilobetin, a natural product isolated and purified from the leaves of Ginkgo biloba L., whose treatment ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats by stimulating PPAR-mediated lipid catabolism.
CSN10380 Bavachinin 19879-30-2 Bavachinin is an agonist of PPAR with EC50s of 4.0 M, 8.1 M, and 0.74 M for ,, and respectively. It is a natural flavanone with anti-angiogenic effect.
CSN18081 Balaglitazone 199113-98-9 Balaglitazone is a partial agonist of PPAR-.
CSN22706 BADGE 1675-54-3 BADGE is a PPARγ antagonist.
CSN20493 Astaxanthin   472-61-7 Astaxanthin is a carotenoid pigment found primarily in marine organisms including Haematococcus Pluvialis, shrimp and salmon. It is a potent lipid-soluble antioxidant.
CSN22075 MBX 102 24136-23-0 Arhalofenate is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ ans is used for the treatment of type 2 diabetes.
CSN20181 AMG-131 315224-26-1 AMG-131 is a hypoglycemic agent It is a potent PPAR partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs
CSN16319 Alpinetin 36052-37-6 Alpinetin can act as an inhibitor of UCK2 and shows antioxidant, anticancer and antithrombotic properties. Alpinetin is mainly found in ginger plants.
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