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PLK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN18009 | Poloxime | 17302-61-3 | Poloxime is an analogue of thymoquinone which bind to the phosphoserinephosphothreonine recognition site of the polo-box domain of polo-like kinase 1 |
| CSN16519 | HMN-214 | 173529-46-9 | HMN-214 is a potent PLK1 inhibitor an average IC50 of 012 M and a prodrug of HMN-176 which alters the cellular spatial orientation of Plk1 |
| CSN19103 | HMN-176 | 173529-10-7 | HMN-176 is the active derivative of HMN-214 which can alter the cellular spatial orientation of Plk1 |
| CSN12461 | BI-2536 | 755038-02-9 | BI-2536 is a potent Plk1 inhibitor with IC50 of 083 nM BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3 and also is a BRD4 inhibitor IC50 25 nM |
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