Protein Kinase D | Apoptosis| CSNpharm

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Anti-infection Antibacterial Antifungal Antiparasitic CMV Filovirus HBV HCV HIV HIV Integrase HIV Protease HRV HSV Influenza Virus NNRTI NRTI Orthopoxvirus Reverse Transcriptase RSV SARS-CoV CCR Dengue Virus H37Rv HHV LpxC Neuraminidase NS2B-NS3 Protease Prion SQLE Antiviral β-lactamase 3CLpro M2 proton channel Antiprotozoal FIP Viral MTase
Apoptosis Apoptosis Inducer Bcl-2 Caspase c-Myc c-RET DAPK IAP MDM2 p53 PD-1/PD-L1 PERK PKD Survivin Thymidylate Synthase TNF-alpha
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Cell Cycle APC Aurora Kinase Casein Kinase CDK Chk c-Myc CRISPR/Cas9 CRM1 DHFR DNA/RNA Synthesis DUB DYRK eIF G-quadruplex Haspin Kinase HSP IRE1 Kinesin LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PD-1/PD-L1 PERK PLK PPAR PTEN RAD51 Rho ROCK Wee1 BUB HSF Mad2 p21 E1/E2/E3 Enzyme FOXM1 MKLP TACC
Cytoskeleton Akt Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK Wnt β-catenin Selectin Arp2/3 Complex PKC Spastin MLCK TACC
DNA Damage ATM/ATR DNA/RNA Synthesis DNA Alkylator/Crosslinker DNA-PK HDAC MTH1 PARP Sirtuin Telomerase Topoisomerase OGG ATAD5
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Immunology/Inflammation CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTR MALT1 NADPH Oxidase NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK STING Thrombopoietin Receptor TLR Calcineurin Complement Receptor IL IRF3 MIF S100A9 TSPO cGAS Immunology & Inflammation Related LTA4H MYD88 NFAT FPR
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LIF/Stat3 LIF
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Membrane Transporter/Ion Channel AMPAR BCRP CFTR Chloride Channel CRAC Channel CRM1 EAAT2 HCN Channel MAT MCT Na+/Ca2+ Exchanger NKCC P2X Receptor P-gp Potassium Channel Proton Pump Sodium Channel TRPV URAT1 VDAC GABA Receptor IBAT Oct SGLT AChR ATPase Calcium Channel EAAT1 GlyT1 Na+/K+ ATPase NBC NMDAR TRP Channel SLC PIEZO1 UCP ENT GABA transporter Glycine transporter Kainate receptor ABC Transporter
Metabolic Enzyme 15-PGDH ACC ACE Adenosine Deaminase Adenosine Kinase AhR ALDH Aldose Reductase Aminopeptidase ATP Citrate Lyase Carbonic Anhydrase Cathepsin CETP COMT CPA Decarboxylase Dehydrogenase DGAT DHFR Elastase Enolase FAAH FABP Factor Xa FAS Ferroptosis FXR Glucokinase GLUT1 GSNOR GST Hexokinase HIF HIV Integrase HMGCR HSP Hydroxylase IDH IDO Lipase Lipoxygenase LXR MAO Mineralocorticoid Receptor NAE NAMPT Neprilysin P450 PAI-1 More >>
Neuronal Signaling AChE Adenosine Kinase Adrenergic Receptor AMPAR Amyloid-β CaMK CGRP Receptor COMT COX DAT Dopamine Receptor FAAH GABA Receptor GlyT1 Histamine Receptor Imidazoline Receptor MAO mGluR MT Receptor NK Receptor NMDAR Opioid Receptor OX Receptor P2X Receptor P-gp Secretase SSRIs Substance P Choline Cholinesterase Enkephalinase Glucosylceramide Synthase NET PSD-95 RAGE SERT 5-HT Receptor AChR PIEZO1 Proprotein convertases QC AQP4 CHT GABA transporter Glycine transporter Kainate receptor
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN RSK FOXO PHLPP
Protease Caspase Cysteine Protease DPP4 Glutaminase HIV Protease MMP Proteasome Secretase Ser/Thr Protease NEP PE Aspartic Protease Tyrosinase DPP2
Protein Tyrosine Kinase/RTK Ack1 ALK Bcr-Abl BMX Kinase BTK c-FMS c-Kit c-Met/HGFR c-RET DDR1/DDR2 Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 HER2 IGF-1R Insulin Receptor ITK PDGFR PKA PTK Pyk2 Src Syk TAM Receptor Tie-2 Trk Receptor VEGFR BRK FGF Tec
Stem Cells/Wnt Casein Kinase ERK Gli GSK-3 Hedgehog JAK MST Notch PKA PORCN ROCK Secretase sFRP-1 Smo STAT Wnt YAP β-catenin BMI-1 TGF-beta Receptor CREB Hes1
TGF-beta/Smad TGF-beta Receptor Smad TGF-beta Smurf
Phosphatase
Ubiquitin APC DUB NAE p97 Proteasome E1/E2/E3 Enzyme SUMO
NF-κB HDAC IKK MALT1 NF-κB NOD1 Nrf2 PPAR RIP Kinase TAK1
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Others Phosphatase SRPK Cardiolipin Peroxidase Diuretic DUE-B E2F ECE FANCJ FAP Fer/FerT Fucosyltransferase Galectin-3 GBF1 GCase HIPK2 HPPD Insecticide LAT1 MLKL MPO MPTP MTP MTTP NMD NO Synthesis Nur77 PAX2 PBR PCA1 PCSK9 PDX1 PFKFB3 Phosphorylase PIN1 PKG Platelet Protein Synthesis Rev-ErbA SAP Serine Hydrolase SQS SREBP STK33 Sweetener Tgase TIR1 UGT1A1 Urease Vanin More >>
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PKD

PKD

PKD

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Cat. No.	Product Name	CAS No.	Information
CSN16110	kb NB 142-70	1233533-04-4	kb NB 142-70 is a selective protein kinase D PKD inhibitor IC50 values are 283 587 and 532 nM for PKD1 2 and 3 respectively
CSN22547	CRT0066101	1883545-60-5	CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins.
CSN13787	CID-755673	521937-07-5	CID-755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM and exhibits selective PKD1 inhibition when compared with AKT PLK1 CAK CAMKII and PKC isoforms
CSN15791	CID-2011756	638156-11-3	CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells

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