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PKD
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN16110 | kb NB 142-70 | 1233533-04-4 | kb NB 142-70 is a selective protein kinase D PKD inhibitor IC50 values are 283 587 and 532 nM for PKD1 2 and 3 respectively |
| CSN22547 | CRT0066101 | 1883545-60-5 | CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins. |
| CSN13787 | CID-755673 | 521937-07-5 | CID-755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM and exhibits selective PKD1 inhibition when compared with AKT PLK1 CAK CAMKII and PKC isoforms |
| CSN15791 | CID-2011756 | 638156-11-3 | CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells |
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