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PI3K

PI3K

Cat. No. Product Name CAS No. Information
CSN13129 Quercetin Dihydrate   6151-25-3 Quercetin Dihydrate inhibits various proteins including tyrosine protein kinase, mitochondrial phospholipase A2 and phosphodiesterases. It is a flavonoid with anticancer activity via suppressing type II estrogen receptors and blocking cell cycle progression. Quercetin could be found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine etc..
CSN27247 PIK-75   372196-67-3 PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM.
CSN11346 LY294002   154447-36-6 LY294002 is the first synthetic molecule known to inhibit p110α, p110β and p110δ with IC50 of 0.5 μM, 0.57 μM, 0.97 μM.
CSN12216 Wortmannin 19545-26-7 KY 12420 is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. It also blocks autophagosome formation and potently inhibits DNA-PKATM with IC50 of 16 nM and 150 nM in cell-free assays.
CSN22904 IITZ-01   1807988-47-1 IITZ-01 is an inhibitor of lysosomotropic autophagy It can enhance autophagosome accumulation and inhibit autophagosomal degradation that finally resulting in the inhibition of autophagy
CSN12350 Acacetin   480-44-4 Acacetin shows inhibiton of the proliferation and induction apoptosis for cancer cells. It is a flavonoid purified from the bark of acacia farnesiana with anti-peroxidant, antiarthritic, and anti-inflammatory activities,
CSN19389 3-Methyladenine   5142-23-4 3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3K with IC50 of 25 M and 60 M.
CSN13521 1,3-O-Dicaffeoylquinic Acid 19870-46-3 1,3-O-Dicaffeoylquinic acid is a natural product isolated and purified from the herbs of Cynara scolymus L., which may activates PI3KAkt.
CSN25447 Erucic acid 112-86-7
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