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Phosphorylase

Phosphorylase

Cat. No. Product Name CAS No. Information
CSN17223 Tipiracil hydrochloride 183204-72-0 Tipiracil HCl is an inhibitor of thymidine phosphorylase (TPase) with IC50 of 35 nM. It has been used in the combination therapy of metastatic colorectal cancer.
CSN21983 Trifluridine/tipiracil hydrochloride mixture 733030-01-8 TAS-102 is an oral combination drug consisting of trifluridine (FTD), which is a thymidine-based nucleoside analog, and tipiracil HCl (TPI), which improves the bioavailability of FTD by inhibiting its catabolism by thymidine phosphorylase (TP).
CSN28966 MT-DADMe-ImmA 653592-04-2 MT-DADMe-ImmA, a chemically stable analogue for the proposed transition state of human MTAP, is a novel MTAP inhibitor with potential for the treatment of human head and neck and prostate carcinoma.
CSN22431 Ingliforib 186392-65-4 Ingliforib is a glycogen phosphorylase inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity.
CSN10057 Doxifluridine   3094-09-5 Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 M.
CSN21273 AVE5688 613260-13-2 AVE5688 is an inhibitor of glycogen phosphorylase GP with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase rmGPb and rmGPa respectively can be used for the research of type 2 diabetes
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