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PERK

PERK

Cat. No. Product Name CAS No. Information
CSN20416 ISRIB 548470-11-7 trans-ISRIB is an Integrated Stress Response Inhibitor trans-ISRIB inhibits the eIF2 phosphorylation-mediated unfolded protein response following induction of ER stress IC50 5 nM in a cell-reporter assay
CSN11888 Salubrinal     405060-95-9 Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit eIF2 dephosphorylation
CSN17942 ISRIB trans-Isomer   1597403-47-8 ISRIB is a potent inhibitor of PERK signaling showing inhibition of the ATF4 luciferase reporter in HEK293T cells with IC50 of 5 nM
CSN15812 GSK2656157 1337532-29-2 GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC50 of 09 nM and is highly selective for PERK with IC50 values 100 nM against a panel of 300 kinases
CSN15902 GSK2606414   1337531-36-8 GSK2606414 is an orally available potent and selective PERK inhibitor with an IC50 of 04 nM
CSN15903 GSK PERK Inhibitor 1337531-89-1 GSK PERK inhibitor is a biochemical for proteomics research
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