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PDK is a kinase enzyme which acts to inactivate the enzyme pyruvate dehydrogenase by phosphorylating it using ATP.
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN17379 | PDK1 Inhibitor | 1001409-50-2 | PDK1 inhibitor is a potent and selective inhibitor of PDK1 with potential as anticancer agent |
| CSN25617 | PDK-4 Inhibitor compound 8c HCl | 2310262-11-2 | PDK-4 Inhibitor compound 8c HCl is an allosteric PDK-4 inhibitor with IC50 value of 84nM. |
| CSN27211 | JX06 | 729-46-4 | JX06 is a selective covalent PDK1 inhibitor with IC50 values of 49, 101 and 313nM for PDK-1, PDK-2 and PDK-3, respectively. |
| CSN17589 | GSK2334470 | 1227911-45-6 | GSK2334470 is a PDK1 inhibitor with IC50 of 10 nM with no activity at other close related AGC-kinases |
| CSN12711 | BX795 | 702675-74-9 | BX795 is a potent and selective dual inhibitor of TBK1PDK1 with IC50s of 2 nM6 nM respectively also inhibit Aurora B and IB kinase IKK |
| CSN19146 | BX517 | 850717-64-5 | BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM |
| CSN17175 | BX-912 | 702674-56-4 | BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 PDK1 with IC50 of 12 nM showing 10 fold selectivity over PKA PKC C-Kit EGFR etc |
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