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PD-1/PD-L1

PD-1/PD-L1

Cat. No. Product Name CAS No. Information
CSN17334 BMS-202   1675203-84-5 PD1-PDL1 inhibitor 2 is an inhibitor of the PD-1 (Programmed death- 1) PD-Ll (Programmed death-ligand 1) proteinprotein interaction with IC50 of 18 nM.
CSN16212 PD1-PDL1 Inhibitor 1 1675201-83-8 PD-1PD-L1 inhibitor 1 is a small-molecule inhibitor of PD-1PD-L1 interaction with IC50 of 6 nM.
CSN19235 PD1-PDL1 Inhibitor 3 1629654-95-0 PD-1/PD-L1 Inhibitor 3 is capable of inhibiting the interaction of PD-L1 with PD-1 and with CD80.
CSN20303 PD-1-PDL1 Inhibitor C2a HCl N/A PD-1-PD-L1 inhibitor C2a is a potential inhibitor of PD-1PD-L1 interaction by inducing an enlarged interaction interface that results in the open face-back tunnel through the PD-L1 dimer
CSN20302 PD-1-PDL1 Inhibitor C1a HCl 2108101-94-4 PD-1-PD-L1 inhibitor C1a is a potential inhibitor of PD-1PD-L1 interaction which exhibits the structures capped on one side of the channel of PD-L1 homodimer
CSN23861 PD1-IN-1 1673560-66-1 PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM[1].
CSN24495 BMS-1166 1818314-88-3 BMS-1166 can disrupt PD-1/PD-L1 interaction with IC50 value of 1.4nM. It can antagonize the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
CSN24471 AUPM-170 1673534-76-3 AUPM-170 is one of CA-170 analogues extracted from patent WO 2015033299 A1, compound example 4.
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