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PARP
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN13901 | Rucaparib Phosphate | 459868-92-9 | Rucaparib phosphate is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. |
| CSN13914 | Rucaparib | 283173-50-2 | Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. |
| CSN17163 | PJ34 | 344458-19-1 | PJ34 is a potent specific inhibitor of PARPl2 with IC50 of 110 nM and 86 nM respectively |
| CSN13594 | PJ34 HCl | 344458-15-7 | PJ34 HCl is a potent specific inhibitor of PARP-l2 with IC50 of 110 nM and 86 nM |
| CSN11806 | Picolinamide | 1452-77-3 | Picolinamide is found to be a strong inhibitor of poly ADP-ribose synthetase of nuclei from rat pancreatic islet cells |
| CSN27556 | Nudifloramide | 701-44-0 | Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro. |
| CSN10181 | NU1025 | 90417-38-2 | NU1025 is a potent PARP inhibitor with IC50 of 400 nM |
| CSN16905 | MN-64 | 92831-11-3 | MN-64 is an inhibitor of tankyrases showed 6 nM potency against tankyrase 1 isoenzyme selectivity and Wnt signaling inhibition |
| CSN13146 | MK-4827 | 1038915-60-4 | MK-4827 is an excellent PARP1 and PARP2 inhibitor with IC50 of 38 and 21 nM respectively |
| CSN17047 | INO-1001 | 3544-24-9 | INO-1001 is a potent inhibitor of PARP with IC50 of 50 nM in CHO cells and a mediator of oxidant-induced myocyte dysfunction during reperfusion. |
| CSN24184 | GeA-69 | 2143475-98-1 | GeA-69 is a selective PARP14 inhibitor with Kd value of 2.1 µM, targeting on macrodomain 2. |
| CSN25274 | BYK204165 | 1104546-89-5 | BYK204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). |
| CSN12304 | BSI-201 | 160003-66-7 | BSI-201 is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). |
| CSN12304 | BSI-201 | 160003-66-7 | BSI-201 is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). |
| CSN12830 | BGP-15 | 66611-37-8 | BGP-15 is a nicotinic amidoxime derivative with PARP inhibitory activity It has been demonstrated that BGP-15 protects against ischemia-reperfusion injury |
| CSN22652 | 4-HQN | 491-36-1 | 4-HQN is a PARP inhibitor with IC50 of 95 M |
| CSN23547 | 3-Methoxybenzamide | 5813-86-5 | 3-Methoxybenzamide is a competitive poly(ADP-ribose) synthetase inhibitor with Ki value < 2 μM and also inhibits ADP-ribosyltransferase (ADPRT). |
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