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PAFR

PAFR

Cat. No. Product Name CAS No. Information
CSN22535 YM-264 131888-54-5 YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes.
CSN14378 Yangambin 13060-14-5 Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role.
CSN21880 Tulopafant 116289-53-3 Tulopafant is a platelet activating factor (PAF) antagonist.
CSN24298 Tcv 309 131311-25-6 TCV-309 is a PAFR (platelet-activating factor receptor) antagonist.
CSN19121 TCV-309 Chloride 121494-09-5 TCV-309 chloride is a platelet activating factor (PAF) antagonist.
CSN22030 Secoisolariciresinol diglucoside 158932-33-3 Secoisolariciresinol diglucoside is an antagonist of platelet activating factor-receptor and used as an antioxidant.
CSN25659 SDZ 62-434 115621-95-9 SDZ 62-434 is a PAF antagonist which showed strong antiproliferative activity (2-40μM)after 24, 48, and 72h of incubation in CCL-121, CCL-218 and HTB-38 cell lines.
CSN21926 Rupatadine Fumarate 1217234-48-4 Rupatadine Fumarate is a dual antagonist of histamine H1 and platelet-activating factor receptors.
CSN14365 Piperenone 57625-31-7 Piperenone a PAF-acether antagonist isolated and purified from the stems of Piper schmidtii Hook f has anti-platelet-activating factorPAF activity
CSN14239 Pinusolide 31685-80-0 Pinusolide, a natural potent and specific PAF antagonist isolated and purified from the barks of Biota orientalis L., inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in immunoglobulin E (IgE)Ag-induced bone marrow-derived mast cells (BMMCs) in a concentration-dependent manner.
CSN19864 PAF (C16) 74389-68-7 PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors.
CSN14342 Niranthin 50656-77-4 Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites.
CSN20856 Ginkgolide K 153355-70-5 Ginkgolide K is a novel naturally small molecule compound isolated from Ginkgo biloba and also acts as a PAF antagonist with potential neuroprotection activity.
CSN12569 Ginkgolide B 15291-77-7 Ginkgolide B an important active terpenoid from Ginkgo biloba leaves a PAFR antagonist with IC50 of 36 M is reported to increase cell viability and decrease cell apoptosis
CSN14643 Futoenone 19913-01-0 Futoenone a natural product isolated and purified from the stem of Piper kadsura inhibitory activities against matrix metalloproteinases the molecular modelings of these compounds indicate the preferred binding of the P2 site of the enzymes and exhibits both platelet activating factor receptorPAFand 5-lipoxygenase antagonist activity
CSN22388 E-6123 131614-02-3 E-6123 is a platelet-activating factor (PAF) receptor antagonist.
CSN22010 48740 RP 93363-11-2 48740 RP (RP-55778) is a platelet-activating factor (PAF) antagonist.
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