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PAFR
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22535 | YM-264 | 131888-54-5 | YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes. |
| CSN14378 | Yangambin | 13060-14-5 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. |
| CSN21880 | Tulopafant | 116289-53-3 | Tulopafant is a platelet activating factor (PAF) antagonist. |
| CSN24298 | Tcv 309 | 131311-25-6 | TCV-309 is a PAFR (platelet-activating factor receptor) antagonist. |
| CSN19121 | TCV-309 Chloride | 121494-09-5 | TCV-309 chloride is a platelet activating factor (PAF) antagonist. |
| CSN22030 | Secoisolariciresinol diglucoside | 158932-33-3 | Secoisolariciresinol diglucoside is an antagonist of platelet activating factor-receptor and used as an antioxidant. |
| CSN25659 | SDZ 62-434 | 115621-95-9 | SDZ 62-434 is a PAF antagonist which showed strong antiproliferative activity (2-40μM)after 24, 48, and 72h of incubation in CCL-121, CCL-218 and HTB-38 cell lines. |
| CSN21926 | Rupatadine Fumarate | 1217234-48-4 | Rupatadine Fumarate is a dual antagonist of histamine H1 and platelet-activating factor receptors. |
| CSN14365 | Piperenone | 57625-31-7 | Piperenone a PAF-acether antagonist isolated and purified from the stems of Piper schmidtii Hook f has anti-platelet-activating factorPAF activity |
| CSN14239 | Pinusolide | 31685-80-0 | Pinusolide, a natural potent and specific PAF antagonist isolated and purified from the barks of Biota orientalis L., inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in immunoglobulin E (IgE)Ag-induced bone marrow-derived mast cells (BMMCs) in a concentration-dependent manner. |
| CSN19864 | PAF (C16) | 74389-68-7 | PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. |
| CSN14342 | Niranthin | 50656-77-4 | Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. |
| CSN20856 | Ginkgolide K | 153355-70-5 | Ginkgolide K is a novel naturally small molecule compound isolated from Ginkgo biloba and also acts as a PAF antagonist with potential neuroprotection activity. |
| CSN12569 | Ginkgolide B | 15291-77-7 | Ginkgolide B an important active terpenoid from Ginkgo biloba leaves a PAFR antagonist with IC50 of 36 M is reported to increase cell viability and decrease cell apoptosis |
| CSN14643 | Futoenone | 19913-01-0 | Futoenone a natural product isolated and purified from the stem of Piper kadsura inhibitory activities against matrix metalloproteinases the molecular modelings of these compounds indicate the preferred binding of the P2 site of the enzymes and exhibits both platelet activating factor receptorPAFand 5-lipoxygenase antagonist activity |
| CSN22388 | E-6123 | 131614-02-3 | E-6123 is a platelet-activating factor (PAF) receptor antagonist. |
| CSN22010 | 48740 RP | 93363-11-2 | 48740 RP (RP-55778) is a platelet-activating factor (PAF) antagonist. |
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