P38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy.
|Cat. No.||Product Name||CAS No.||Information|
|CSN23943||SJFδ||2254609-23-7||SJFδ is a PROTAC selectively targeting on p38δ, consist of a warhead of foretinib linked to VHL-recruiting ligand. SJFδ exhibited DC50/Dmax values of 79.2nM/98.4% and 45.9nM/34.5% for degradation of p38δ and p38α, respectively.|
|CSN23942||SJFα||2254609-27-1||SJFα is a PROTAC selectively targeting on p38α, consist of a warhead of foretinib linked to VHL-recruiting ligand.|