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p38 MAPK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN15958 | TAK-715 | 303162-79-0 | TAK-715 is a p38 MAPK inhibitor for p38 with IC50 of 7.1 nM, being 28-fold selective for p38 over p38, showing no inhibition to p38, JNK1, ERK1, IKK, MEKK1 or TAK1. |
| CSN13149 | SKF-86002 | 72873-74-6 | SKF-86002 is a potent inhibitor of p38 MAP kinase with IC50 of 0.5-1 M and inhibits LPS-induced IL-1 and TNF- production in human monocytes (IC50 1 M). |
| CSN27555 | SD-169 | 1670-87-7 | SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. |
| CSN18176 | SD-06 | 271576-80-8 | SD-06 is a p38 MAP kinase inhibitor and inhibits p38 with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats(83 inhibition at 1mgkg, po). |
| CSN16503 | Scopoletin | 92-61-5 | Scopoletin has important anti-inflammatory activity by inhibiting the phosphorylation of NF-B and p38 MAPK. |
| CSN13746 | SB-242235 | 193746-75-7 | SB-242235 is a potent and selective p38 MAP kinase inhibitor with IC50 of 10 M |
| CSN11899 | SB-203580 | 152121-47-6 | SB-203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 M. |
| CSN11899 | SB-203580 | 152121-47-6 | SB-203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 M. |
| CSN12897 | SB-239063 | 193551-21-2 | SB 239063 is a potent, selective and oral active p38 MAPK inhibitor with IC50 of 44 nM for recombinant purified p38. |
| CSN13817 | PD169316 | 152121-53-4 | PD169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 89 nM). |
| CSN23347 | Methyl Ferulate | 2309-07-1 | Methyl Ferulate is a naturally-occurring phenolic with antioxidant activities and inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages. |
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