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P-gp
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12903 | Zosuquidar | 167354-41-8 | Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60 at 2 and 10M and had no effect at 008 and 04M measured by P-gp ATPase activity |
| CSN12751 | Zosuquidar 3HCl | 167465-36-3 | Zosuquidar 3HCl is the 3HCl form of Zosuquidar. Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60% at 2 and 10μM and had no effect at 0.08 and 0.4μM. |
| CSN12182 | Valspodar | 121584-18-7 | Valspodar is a P-glycoprotein P-gp inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance MDR |
| CSN12910 | Tariquidar | 206873-63-4 | Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 51 nM reverses drug resistance in MDR cell Lines |
| CSN22057 | Sinapine | 18696-26-9 | Sinapine is an alkaloid from seeds of the cruciferous species which shows antioxidant and radio-protective activities and decreases expression of P-glycoprotein in Caco-2 cells. |
| CSN19434 | Schizandrin | 7432-28-2 | Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities. |
| CSN25413 | RCGD423 | 108237-91-8 | RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair. |
| CSN13555 | Isosinensetin | 17290-70-9 | Isosinensetin exhibits HIV-1 protease inhibiting and antioxidant activities. It is a natural product isolated and purified from the fruit of Citrus aurantium L.. |
| CSN23176 | UCLA GP130 2 | 339303-87-6 | gp130-agonist-2 is a brain penetrant gp130 agonist which protects against NMDA-induced toxicity and increases STAT3 phosphorylation. |
| CSN10894 | Elacridar | 143664-11-3 | Elacridar is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. |
| CSN13175 | Elacridar HCl | 143851-98-3 | Elacridar HCl is a P-glycoprotein (P-gp) inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-gp to investigate the role of transporters in the disposition of various test molecules. |
| CSN17662 | Dofequidar | 129716-58-1 | Dofequidar is a quinoline compound which can reverse P-glycoprotein P-gp-mediated MDR |
| CSN22768 | CP 100356 HCl | 142715-48-8 | CP 100356 HCl is a high affinity P-glycoprotein (P-gp) inhibitor with Kis of 58 and 94 nM for mouse Pgp1a and Pgp1b isoforms. |
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