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P-gp
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12751 | Zosuquidar 3HCl | 167465-36-3 | Zosuquidar 3HCl is the 3HCl form of Zosuquidar. Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60% at 2 and 10μM and had no effect at 0.08 and 0.4μM. |
| CSN12910 | Tariquidar | 206873-63-4 | Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 51 nM reverses drug resistance in MDR cell Lines |
| CSN22057 | Sinapine | 18696-26-9 | Sinapine is an alkaloid from seeds of the cruciferous species which shows antioxidant and radio-protective activities and decreases expression of P-glycoprotein in Caco-2 cells. |
| CSN19434 | Schizandrin | 7432-28-2 | Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities. |
| CSN25413 | RCGD423 | 108237-91-8 | RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair. |
| CSN13555 | Isosinensetin | 17290-70-9 | Isosinensetin exhibits HIV-1 protease inhibiting and antioxidant activities. It is a natural product isolated and purified from the fruit of Citrus aurantium L.. |
| CSN10894 | Elacridar | 143664-11-3 | Elacridar is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. |
| CSN17662 | Dofequidar | 129716-58-1 | Dofequidar is a quinoline compound which can reverse P-glycoprotein P-gp-mediated MDR |
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