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P-gp

P-gp

Cat. No. Product Name CAS No. Information
CSN12903 Zosuquidar 167354-41-8 Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60 at 2 and 10M and had no effect at 008 and 04M measured by P-gp ATPase activity
CSN12751 Zosuquidar 3HCl 167465-36-3 Zosuquidar 3HCl is the 3HCl form of Zosuquidar. Zosuquidar is P-gp modulator that inhibited Pgp-ATPase activity 50-60% at 2 and 10μM and had no effect at 0.08 and 0.4μM.
CSN12182 Valspodar 121584-18-7 Valspodar is a P-glycoprotein P-gp inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance MDR
CSN12910 Tariquidar 206873-63-4 Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 51 nM reverses drug resistance in MDR cell Lines
CSN22057 Sinapine 18696-26-9 Sinapine is an alkaloid from seeds of the cruciferous species which shows antioxidant and radio-protective activities and decreases expression of P-glycoprotein in Caco-2 cells.
CSN19434 Schizandrin   7432-28-2 Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities.
CSN25413 RCGD423 108237-91-8 RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.
CSN13555 Isosinensetin 17290-70-9 Isosinensetin exhibits HIV-1 protease inhibiting and antioxidant activities. It is a natural product isolated and purified from the fruit of Citrus aurantium L..
CSN23176 UCLA GP130 2 339303-87-6 gp130-agonist-2 is a brain penetrant gp130 agonist which protects against NMDA-induced toxicity and increases STAT3 phosphorylation.
CSN10894 Elacridar   143664-11-3 Elacridar is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules.
CSN13175 Elacridar HCl 143851-98-3 Elacridar HCl is a P-glycoprotein (P-gp) inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-gp to investigate the role of transporters in the disposition of various test molecules.
CSN17662 Dofequidar 129716-58-1 Dofequidar is a quinoline compound which can reverse P-glycoprotein P-gp-mediated MDR
CSN22768 CP 100356 HCl 142715-48-8 CP 100356 HCl is a high affinity P-glycoprotein (P-gp) inhibitor with Kis of 58 and 94 nM for mouse Pgp1a and Pgp1b isoforms.
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