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Cat. No. Product Name CAS No. Information
CSN22262 VH-032 1448188-62-2 VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHLHIF-1 interaction with Kd of 185 nM.
CSN22297 Gefitinib-Based PROTAC 3 2230821-27-7 Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).
CSN23768 E3 ligase Ligand 5 1264754-13-3 E3 ligase Ligand 5 is a ligand of E3 ligase, extracted from patent US 20160058872A1, Paragraph 0515.
CSN22288 CCT-367766 2229856-58-8 CCT-367766 (CCT367766) is a heterobifunctional PROTAC that binds and degrades the putative transcription factor regulator Pirin in cells.
CSN22261 VHL Ligand 3 1448189-98-7 A VHL ligand for PROTAC.
CSN22260 Bis-PEG5-acid 77855-75-5 A PEG linker for PROTAC.
CSN22276 Bis-PEG6-acid 77855-76-6 A PEG linker for PROTAC.
CSN22312 CM11 N/A A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines, in a highly isoform-selective fashion and without triggering a hypoxic response a chemical probe for selective VHL knockdown.
CSN25475 5-Ethynyl-2'-dU 61135-33-9 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker.
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