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Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

Cat. No. Product Name CAS No. Information
CSN23440 Uridin 58-96-8 Uridin is a nucleoside and one of main component in RNA.
CSN21870 Triciribine Phosphate 61966-08-3 Triciribine Phosphate is a DNA synthesis inhibitor, also inhibits Akt and HIV-1/2 with IC50 of 130 nM, and 0.02-0.46 μM, respectively.
CSN13929 Tipiracil 183204-74-2 Tipiracil is a thymidine phosphorylase TPase inhibitor
CSN17223 Tipiracil HCl 183204-72-0 Tipiracil HCl is an inhibitor of thymidine phosphorylase (TPase) with IC50 of 35 nM. It has been used in the combination therapy of metastatic colorectal cancer.
CSN21983 Lonsurf 733030-01-8 TAS-102 is an oral combination drug consisting of trifluridine (FTD), which is a thymidine-based nucleoside analog, and tipiracil HCl (TPI), which improves the bioavailability of FTD by inhibiting its catabolism by thymidine phosphorylase (TP).
CSN23840 Sapacitabine 151823-14-2 Sapacitabine is an orally available nucleoside analog prodrug that is structurally related to cytarabine.
CSN21152 Guadecitabine Sodium 929904-85-8 Same as guadecitabine is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine with potential antineoplastic activity
CSN16876 RX-3117 865838-26-2 RX-3117 is a cytidine analog showing anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.
CSN17509 Mycophenolate Mofetil HCl 116680-01-4 Mycophenolate mofetil HCl, is an immunosuppressant drug used to prevent rejection in organ transplantation.
CSN18532 LY2334737 892128-60-8 LY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy
CSN20570 Guadecitabine 929901-49-5 Guadecitabine aslo known as SGI-110 is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine with potential antineoplastic activity
CSN18105 Gemcitabine Elaidate 210829-30-4 Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.
CSN13668 Fodosine 209799-67-7 Forodesine is an orally bioavailable PNP inhibitor with picomolar potency and induces apoptosis, mainly in T cells.
CSN18179 Forodesine HCl 284490-13-7 Forodesine HCl is an orally bioavailable PNP inhibitor with picomolar potency and induces apoptosis, mainly in T cells.
CSN24306 Cytidine 65-46-3 Cytidine is a non-essential aminoacid.
CSN10734 Cytarabine HCl   69-74-9 Cytarabine HCl is the hydrochloride form of Cytarabine. Cytarabine (Ara-C) is an antineoplastic and antileukemic agent in current clinical treatment.
CSN22029 CNDAC 135598-68-4 CNDAC is a major metabolite of oral drug sapacitabine and a nucleoside analog.
CSN12531 Azaguanine-8   134-58-7 Azaguanine-8 is a purine analog showing antineoplastic activity by competing with guanine in the metabolism.
CSN13714 6-Thioguanine   154-42-7 6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites, and is a purine analogue of the nucleobase guanine. It was found to inhibit SARS-CoV PLpro.
CSN25514 6-Mercaptopurine-9-β-D-ribofuranoside 574-25-4 6-Mercaptopurine-9-β-D-ribofuranoside is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα[1][2].
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