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Nucleoside Antimetabolite/Analog
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN23440 | Uridin | 58-96-8 | Uridin is a nucleoside and one of main component in RNA. |
| CSN21870 | Triciribine Phosphate | 61966-08-3 | Triciribine Phosphate is a DNA synthesis inhibitor, also inhibits Akt and HIV-1/2 with IC50 of 130 nM, and 0.02-0.46 μM, respectively. |
| CSN13929 | Tipiracil | 183204-74-2 | Tipiracil is a thymidine phosphorylase TPase inhibitor |
| CSN17223 | Tipiracil HCl | 183204-72-0 | Tipiracil HCl is an inhibitor of thymidine phosphorylase (TPase) with IC50 of 35 nM. It has been used in the combination therapy of metastatic colorectal cancer. |
| CSN21983 | Lonsurf | 733030-01-8 | TAS-102 is an oral combination drug consisting of trifluridine (FTD), which is a thymidine-based nucleoside analog, and tipiracil HCl (TPI), which improves the bioavailability of FTD by inhibiting its catabolism by thymidine phosphorylase (TP). |
| CSN23840 | Sapacitabine | 151823-14-2 | Sapacitabine is an orally available nucleoside analog prodrug that is structurally related to cytarabine. |
| CSN21152 | Guadecitabine Sodium | 929904-85-8 | Same as guadecitabine is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine with potential antineoplastic activity |
| CSN16876 | RX-3117 | 865838-26-2 | RX-3117 is a cytidine analog showing anticancer activity in several cancer cell lines, including gemcitabine-resistant variants. |
| CSN17509 | Mycophenolate Mofetil HCl | 116680-01-4 | Mycophenolate mofetil HCl, is an immunosuppressant drug used to prevent rejection in organ transplantation. |
| CSN18532 | LY2334737 | 892128-60-8 | LY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy |
| CSN20570 | Guadecitabine | 929901-49-5 | Guadecitabine aslo known as SGI-110 is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine with potential antineoplastic activity |
| CSN18105 | Gemcitabine Elaidate | 210829-30-4 | Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. |
| CSN13668 | Fodosine | 209799-67-7 | Forodesine is an orally bioavailable PNP inhibitor with picomolar potency and induces apoptosis, mainly in T cells. |
| CSN18179 | Forodesine HCl | 284490-13-7 | Forodesine HCl is an orally bioavailable PNP inhibitor with picomolar potency and induces apoptosis, mainly in T cells. |
| CSN24306 | Cytidine | 65-46-3 | Cytidine is a non-essential aminoacid. |
| CSN10734 | Cytarabine HCl | 69-74-9 | Cytarabine HCl is the hydrochloride form of Cytarabine. Cytarabine (Ara-C) is an antineoplastic and antileukemic agent in current clinical treatment. |
| CSN22029 | CNDAC | 135598-68-4 | CNDAC is a major metabolite of oral drug sapacitabine and a nucleoside analog. |
| CSN12531 | Azaguanine-8 | 134-58-7 | Azaguanine-8 is a purine analog showing antineoplastic activity by competing with guanine in the metabolism. |
| CSN13714 | 6-Thioguanine | 154-42-7 | 6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites, and is a purine analogue of the nucleobase guanine. It was found to inhibit SARS-CoV PLpro. |
| CSN25514 | 6-Mercaptopurine-9-β-D-ribofuranoside | 574-25-4 | 6-Mercaptopurine-9-β-D-ribofuranoside is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα[1][2]. |
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