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Nrf2

Nrf2

Cat. No. Product Name CAS No. Information
CSN23062 RA 839 1832713-02-6 RA-839 is a noncovalent small molecule binder to Keap1 and selective activator of Nrf2 signaling. RA-839 also suppresses LPS-induced iNOS and nitric oxide expression in macrophages.
CSN19067 NK-252 1414963-82-8 NK-252 is a Nrf2 activator, exhibits a greater Nrf2-activating potential than OPZ.
CSN22981 MMF   2756-87-8 MMF can induce Nrf2 activation
CSN22320 ML385 846557-71-9 ML-385 is a selective inhibitor of NRF2 via binding to Neh1 DNA binding domain with IC50 of 19 M
CSN16363 Mangiferin   4773-96-0 Mangiferin is the predominant constituent of extracts of the mango plant Mangifera Indica L. with potential antidiabetic activity.
CSN21243 KI696 1799974-70-1 KI696 is a high affinity probe that disrupts the Keap1NRF2 interaction.
CSN22428 Hesperin 4430-35-7 Hesperin is a bioactive ingredient present in Japanese horseradish wasabi and has been shown to be an Nrf2 activator
CSN17434 Ginsenoside Rh3 105558-26-7 Ginsenoside Rh3, a natural product isolated and purified from the roots of Panax ginseng C.
CSN10136 Farrerol 24211-30-1 Farrerol is a natural product isolated and purified from the leaves of Rhododendron dauricum L.
CSN10930 Eriodictyol-7-O-Glucoside 38965-51-4 Eriodictyol-7-O-glucoside, a natural product isolated and purified from the herbs of Dracocephalum rupestre, can activate Nrf2ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic, suggesting that targeting the Nrf2ARE pathway may be a promising approach for therapeutic intervention in stroke.
CSN18597 CDDO-EA 932730-51-3 CDDO-EA is an activator of Nrf2ARE with neuroprotective effect.
CSN15955 Astilbin 29838-67-3 Astilbin is a flavonoid compound that can enhance NRF2 activition with anti-inflammatory properties. It could be extracted from chinese astilbe. Astilbin has been found to have significant immunosuppressive effects in recent years.
CSN19355 AKBA 67416-61-9 AKBA is a novel Nrf2 activator which can increase basal and UVA-induced levels of Nrf2
CSN23667 4-Octyl Itaconate   3133-16-2 4-Octyl itaconate is the endogenous metabolite of itaconate with anti-inflammatory activity. It can decrease cytokine production and protect against lipopolysaccharide-induced lethality in vivo.
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