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Nrf2
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12060 | TBHQ | 1948-33-0 | TBHQ is a synthetic aromatic organic compound used as an antioxidant and preservative. |
| CSN23062 | RA839 | 1832713-02-6 | RA-839 is a noncovalent small molecule binder to Keap1 and selective activator of Nrf2 signaling. RA-839 also suppresses LPS-induced iNOS and nitric oxide expression in macrophages. |
| CSN19067 | NK-252 | 1414963-82-8 | NK-252 is a Nrf2 activator, exhibits a greater Nrf2-activating potential than OPZ. |
| CSN22981 | Monomethyl fumarate | 2756-87-8 | MMF can induce Nrf2 activation |
| CSN22320 | ML385 | 846557-71-9 | ML-385 is a selective inhibitor of NRF2 via binding to Neh1 DNA binding domain with IC50 of 19 M |
| CSN16363 | Mangiferin | 4773-96-0 | Mangiferin is the predominant constituent of extracts of the mango plant Mangifera Indica L. with potential antidiabetic activity. |
| CSN21243 | KI696 | 1799974-70-1 | KI696 is a high affinity probe that disrupts the Keap1NRF2 interaction. |
| CSN10136 | Farrerol | 24211-30-1 | Farrerol is a natural product isolated and purified from the leaves of Rhododendron dauricum L. |
| CSN29518 | Ezetimibe ketone | 191330-56-0 | Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor.Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. |
| CSN10930 | Eriodictyol-7-O-glucoside | 38965-51-4 | Eriodictyol-7-O-glucoside, a natural product isolated and purified from the herbs of Dracocephalum rupestre, can activate Nrf2ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic, suggesting that targeting the Nrf2ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CSN13701 | Dimethyl fumarate | 624-49-7 | Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator which induces upregulation of antioxidant gene expression. |
| CSN15955 | Astilbin | 29838-67-3 | Astilbin is a flavonoid compound that can enhance NRF2 activition with anti-inflammatory properties. It could be extracted from chinese astilbe. Astilbin has been found to have significant immunosuppressive effects in recent years. |
| CSN19355 | AKBA | 67416-61-9 | AKBA is a novel Nrf2 activator which can increase basal and UVA-induced levels of Nrf2 |
| CSN25689 | 1-Chloro-3-methanesulfonyl-6,6-dimethyl-4,5,6,7-tetrahydro-2-benzothiophen-4-one | 882288-28-0 | AI-3 is an antivator of antioxidant response element (ARE). It can disrupt Nrf2/Keap1 and Keap1/Cul3 interactions and stabilize Nrf2. |
| CSN23667 | 4-Octyl Itaconate | 3133-16-2 | 4-Octyl itaconate is the endogenous metabolite of itaconate with anti-inflammatory activity. It can decrease cytokine production and protect against lipopolysaccharide-induced lethality in vivo. |
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