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Notch

Notch

Cat. No. Product Name CAS No. Information
CSN22137 tCFA15 220757-88-0 tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain promotes the differentiation of neurons and may regulates Notchsignaling
CSN27258 SAHM1 2050906-89-1 SAHM1 is a stabilized hydrocarbon-stapled alpha helical peptide targeting Notch pathway. It mimics a dominant negative form of MAML, inhibits canonical Notch transcription complex formation.
CSN27582 RIN1 N/A RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling.
CSN18826 IMR-1A 331862-41-0 IMR-1A is the metabolite of IMR-1 a Notch inhibitor targeting the transcriptional activation
CSN18825 IMR-1   310456-65-6 IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 M for targeting the transcriptional activation
CSN13458 Bruceine D 21499-66-1 Bruceine D, a natural product isolated and purified from the barks of Ailanthus altissima, may have the potential to be used as a natural viricide, or a lead compound for viricides, inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1, and induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
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