Notch
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN27582 | RIN1 | N/A | RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling. |
CSN18826 | IMR-1A | 331862-41-0 | IMR-1A is the metabolite of IMR-1 a Notch inhibitor targeting the transcriptional activation |
CSN13458 | Bruceine D | 21499-66-1 | Bruceine D, a natural product isolated and purified from the barks of Ailanthus altissima, may have the potential to be used as a natural viricide, or a lead compound for viricides, inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1, and induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway. |