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Apoptosis Apoptosis Inducer Bcl-2 Caspase c-Myc c-RET DAPK IAP MDM2 p53 PD-1/PD-L1 PERK PKD Survivin Thymidylate Synthase TNF-alpha
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MAPK/ERK Pathway ERK JNK KLF MEK MLK MNK p38 MAPK Raf RSK MAP4K4
LIF/Stat3 LIF
Membrane Transporter/Ion Channel AChR AMPAR BCRP CFTR Chloride Channel CRAC Channel CRM1 EAAT2 HCN Channel MAT MCT Na+/Ca2+ Exchanger NKCC P2X Receptor P-gp Potassium Channel Proton Pump Sodium Channel TRPV URAT1 VDAC GABA Receptor IBAT Oct SGLT ATPase Calcium Channel EAAT1 GlyT1 Na+/K+ ATPase NBC NMDAR TRP Channel SLC
Metabolic Enzyme 15-PGDH ACC ACE Adenosine Deaminase Adenosine Kinase AhR ALDH Aldose Reductase Aminopeptidase ATP Citrate Lyase Carbonic Anhydrase Cathepsin CETP COMT CPA Decarboxylase Dehydrogenase DGAT DHFR Elastase Enolase FAAH FABP Factor Xa FAS Ferroptosis FXR Glucokinase GLUT1 GSNOR GST Hexokinase HIF HIV Integrase HMGCR HSP Hydroxylase IDH IDO Lipase Lipoxygenase LXR MAO Mineralocorticoid Receptor NAE NAMPT Neprilysin P450 PAI-1 More >>
Neuronal Signaling AChE AChR Adenosine Kinase Adrenergic Receptor AMPAR Amyloid-β CaMK CGRP Receptor COMT COX DAT Dopamine Receptor FAAH GABA Receptor GlyT1 Histamine Receptor Imidazoline Receptor MAO mGluR MT Receptor NK Receptor NMDAR Opioid Receptor OX Receptor P2X Receptor P-gp Secretase SSRIs Substance P Choline Cholinesterase Enkephalinase Glucosylceramide Synthase RAGE 5-HT Receptor
PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN RSK FOXO PHLPP
Protease Caspase Cysteine Protease DPP4 Glutaminase HIV Protease MMP Proteasome Secretase Ser/Thr Protease NEP Aspartic Protease Tyrosinase
Protein Tyrosine Kinase/RTK Ack1 ALK Bcr-Abl BMX Kinase BTK c-FMS c-Kit c-Met/HGFR c-RET DDR1/DDR2 Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 HER2 IGF-1R Insulin Receptor ITK PDGFR PKA PTK Pyk2 Src Syk TAM Receptor Tie-2 Trk Receptor VEGFR BRK
Stem Cells/Wnt Casein Kinase ERK Gli GSK-3 Hedgehog JAK MST Notch PKA PORCN ROCK Secretase sFRP-1 Smo STAT Wnt YAP β-catenin BMI-1
TGF-beta/Smad TGF-beta Receptor Smad TGF-beta
Ubiquitin APC DUB NAE p97 Proteasome E1/E2/E3 Enzyme
Phosphatase
NF-kB HDAC IKK MALT1 NF-kB NOD1 Nrf2 PPAR RIP Kinase TAK1
Others Phosphatase SRPK ECE FANCJ Fucosyltransferase Galectin-3 GBF1 GCase HPPD LAT1 MLKL MPO MTP MTTP NMD Nur77 PCSK9 PFKFB3 Phosphorylase PKG Platelet Protein Synthesis Rev-ErbA Serine Hydrolase SQS STK33 Sweetener Tgase Urease VDA Vitamin XOR Cancer Stem Cells CD73 CerK Chelating Agent ITPKA Legumain OxPhos Others
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Notch

Notch

Notch

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Cat. No.	Product Name	CAS No.	Information
CSN22137	tCFA15	220757-88-0	tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain promotes the differentiation of neurons and may regulates Notchsignaling
CSN15691	LY3039478	1421438-81-4	LY3039478 is a novel potent Notch inhibitor with an IC50 of 041 nM
CSN18826	IMR-1A	331862-41-0	IMR-1A is the metabolite of IMR-1 a Notch inhibitor targeting the transcriptional activation
CSN18825	IMR-1	310456-65-6	IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 M for targeting the transcriptional activation
CSN18205	FLI-06	313967-18-9	FLI-06 is a Notch signaling inhibitor with EC50 of 2.3 μM which can disrupt Notch trafficking and processing.
CSN17939	BMS-983970	1584713-87-0	BMS-983970 is an oral pan-Notch inhibitor for the treatment of cancer

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