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NOS
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN19029 | ZL006 | 1181226-02-7 | ZL006 is a potent inhibitor of nNOSPSD-95 interaction and inhibits NMDA receptor-mediated NO synthesis |
| CSN14855 | Verminoside | 50932-19-9 | Verminoside, a natural product isolated and purified from the barks of Kigelia pinnata with anti-inflammatory effect, inhibits both iNOS expression and NO release in the LPS-induced J774.A1 macrophage cell line. |
| CSN14690 | Triptoquinone A | 142950-86-5 | Triptoquinone A, a natural product isolated and purified from the roots of Tripterygium wilfordii Hook.f. |
| CSN23846 | Tetrahydrobiopterin | 17528-72-2 | Tetrahydrobiopterin is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms. |
| CSN22638 | (S)-Methylisothiourea Sulfate | 867-44-7 | S-Methylisothiourea Sulfate is a highly selective potent and competitive inhibitor of iNOS |
| CSN10641 | prim-O-Glucosylcimifugin | 80681-45-4 | Prim-O-glucosylcimifugin is a natural product isolated and purified from the root of Saposhnikovia divaricata (Turcz.) Schischk., which can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0G1 phase. |
| CSN22647 | Piperidin-2-imine HCl | 16011-96-4 | Piperidin-2-imine HCl is a selective iNOS inhibitor. |
| CSN21155 | L-NMMA Acetate | 53308-83-1 | L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 M, respectively. |
| CSN22944 | L-NIO 2HCl | 159190-44-0 | L-NIO 2HCl is an inhibitor of nitric oxide (NO) synthase, including iNOS, eNOS and nNOS. |
| CSN22943 | L-NIL HCl | 150403-89-7 | L-NIL HCl is a selective inhibitor of inducible nitric oxide synthase with IC50 of 3.3 μM. |
| CSN16603 | L-NAME HCl | 51298-62-5 | L-NAME HCl is a non-selective NOS inhibitor with Ki values of 15 nM 39 nM and 44 M for nNOS bovine eNOS human and iNOS murine respectively |
| CSN22880 | L-Canavanine Sulfate | 2219-31-0 | L-Canavanine Sulfate is a NO synthase inhibitor. |
| CSN15716 | L-Arginine HCl | 1119-34-2 | L-Arginine HCl is a substrate of NOS and a nonessential amino acid in human. |
| CSN20293 | JS-K | 205432-12-8 | JS-K is an antiproliferative nitric oxide donor |
| CSN16369 | Imperatorin | 482-44-0 | Imperatorin is a naturally occuring multiple-target inhibitor of NOS with IC50 value of 9.2 M, BChE with IC50 value of 31.4 M, a potent calcium antagonist on vascular smooth muscle. It is also a weak agonist of TRPV1 with EC50 of 12.63.2 M. |
| CSN19030 | IC-87201 | 866927-10-8 | IC87201 an inhibitor of PSD95-nNOS protein-protein interactions suppresses NMDAR-dependent NO and cGMP formation |
| CSN18103 | GW274150 | 210354-22-6 | GW274150 is an arginine-competitive, NADPH-dependent iNOS inhibitor that has been identified from a series of acetamide amino acids that have a high selectivity for iNOS vs both eNOS ( 260-fold) and nNOS ( 219-fold) and high bioavailability ( 90) after oral administration. |
| CSN22803 | EIT Hydrobromide | 1071-37-0 | EIT Hydrobromide is a potent, selective and reversible inhibitor of isoform II NO synthase with IC50 of 13 nM. |
| CSN12661 | Dehydroevodiamine | 67909-49-3 | Dehydroevodiamine is an alkaloid isolated from E. rutaecarpa and possesses anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities. |
| CSN10310 | Dehydroandrographolide | 134418-28-3 | Dehydroandrographolide is extracted from herbal medicine Andrographis paniculata (Burm f) Nees and alleviates oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS. |
| CSN22730 | BYK 191023 2HCl | 1216722-25-6 | BYK 191023 2HCl is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) with IC50 of 86 nM. |
| CSN22685 | AR-C 102222 | 1781934-50-6 | AR-C 102222 is a selective iNOS inhibitor with IC50 of 0.037 μM. |
| CSN19966 | Apiin | 26544-34-3 | Apiin can inhibit iNOS expression and nitrite production in J774.A1 cells. It is a flavonoid isolated from the herbs of petroselinum crispum. |
| CSN22682 | AMT HCl | 21463-31-0 | AMT HCl is a potent, selective and reversible inhibitor of iNOS with IC50 of 3.6 nM. |
| CSN10284 | Aminoguanidine HCl | 1937-19-5 | Aminoguanidine HCl is a selective and irreversible iNOS inhibitor. |
| CSN23420 | Agmatine sulfate | 2482-00-0 | Agmatine sulfate is a competitive NOS inhibitor |
| CSN23606 | 7-Nitroindazole | 2942-42-9 | 7-Nitroindazole is a competitive reversible and non-selective NOS inhibitor |
| CSN12781 | 2-(2-Aminoethyl)isothiourea dihydrobromide | 56-10-0 | 2-2-Aminoethylisothiourea dihydrobromide inhibits nitric oxide synthase NOS |
| CSN14783 | 15-Methoxypinusolidic Acid | 769928-72-5 | 15-Methoxypinusolidic acid, a natural product isolated and purified from the leaves of Biota orientalis, induces apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression, inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression, and attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors. |
| CSN16858 | 1400W 2HCl | 214358-33-5 | 1400W 2HCl is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase (iNOS). |
| CSN25404 | L-NNA | 2149-70-4 | |
| CSN25443 | 3-Bromo-7-nitroindazole | 74209-34-0 |
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