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NO Synthesis

Cat. No. Product Name CAS No. Information
CSN21831 S-Methyl-L-Thiocitrulline 156719-41-4 S-MTC is a selective NOS inhibitor with selectivity toward the neuronal isoform compared to eNOS and iNOS.
CSN14822 Kazinol B 99624-27-8 Kazinol B, a natural product isolated and purified from the barks of Broussonetia papyrifera, inhibits the NO synthesis with an IC(50) of 21.6 mM, stimulates respiratory burst, is probably mediated by the synergism of PKC activation and [Ca2+]i elevation in rat neutrophils, stimulates Ca(2+) release from internal Ca(2+) store, probably through the sphingosine 1-phosphate and IP(3) signaling, activates external Ca(2+) influx mainly through a non-store-operated Ca(2+) entry (non-SOCE) pathway, and inhibits SOCE, probably attributable to a break in the Ca(2+) driven force of mitochondria.
CSN19905 Crocin II 55750-84-0 Crocin, a natural product with anti-inflammatory, antihyperlipidemic, antidepressant and anti-apoptotic effects, can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite, its isolated and purified from the stigma of Crocus sativus L..
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