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NMDAR

NMDAR

Cat. No. Product Name CAS No. Information
CSN21328 UK-240455 178908-09-3 UK-240455 is a potent and selective N-methyl D-aspartate NMDA glycine site antagonist
CSN24287 Traxoprodil mesylate   189894-57-3 Traxoprodil a selective antagonist of the NR2B subunit of the NMDA receptor.
CSN21414 Transcrocetin meglumine salt N/A Transcrocetin meglumine salt extracted from saffron Crocus sativus L acts as an NMDA receptor antagonist with high affinity
CSN26714 Transcrocetinate disodium 591230-99-8 Trans-crocetin sodium, also known as Transcrocetinate sodium or Sodium crocetinate, is potentially for the treatment of glioblastoma. Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients. trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices. Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.
CSN25802 TCN 201 852918-02-6 TCN-201 is a sulphonamide derivative that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor.
CSN18033 SDZ 220-581 hydrochloride 179411-93-9 SDZ 220-581 HCl is a potent, competitive antagonist at the NMDA glutamate receptor subtype (pKi= 7.7).
CSN18034 SDZ 220-581 Ammonium salt 179411-94-0 SDZ 220-581 ammonium is a potent competitive antagonist at the NMDA glutamate receptor subtype pKi 77
CSN15699 Sarcosine   107-97-1 Sarcosine is an NMDAR co-agonist at the glycine binding site. It is an intermediate and byproduct in glycine synthesis and degradation.
CSN17353 Ro 25-6981 169274-78-6 Ro 25-6981 is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit
CSN26712 Rislenemdaz 808732-98-1 Rislenemdaz, also known as MK-0657, is a NR2B-selective NMDA antagonist potentially for the treatment of Parkinson's disease.
CSN17520 Rapastinel 117928-94-6 Rapastinel is a putative NMDAR functional glycine-site partial agonist
CSN23784 Radiprodil 496054-87-6 Radiprodil is a selective antagonist of NMDA NR2B that used in treatment of neuropathic pain.
CSN16857 QNZ46   1237744-13-6 QNZ46 is a noncompetitive and voltage-independent GluN2CGluN2D-selective NMDA antagonist with IC50 values of 3 6 229 M for GluN2D GluN2C GluN2A respectively
CSN17346 PEAQX 459836-30-7 PEAQX is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A2A IC50270 nM rather than 1A2B29600 nM
CSN19272 PEAQX tetrasodium hydrate N/A PEAQX is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A2A IC50270 nM rather than 1A2B29600 nM
CSN24186 NMDAR antagonist 1 2220162-06-9 NMDAR antagonist 1 is a NR2B-selective NMDAR antagonist.
CSN17347 NMDA-IN-1 700878-19-9 NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 085 nM Its NR2B Ca2 influx IC50 is 97 nM without activities on NR2A NR2C NR2D hERG-channel and 1-adrenergic receptor
CSN13790 NMDA   6384-92-5 NMDA is an amino acid derived specific agonist at the NMDA receptor
CSN29465 L-Cysteinesulfinic acid 1115-65-7 NMDA and mGlu agonist.
CSN11379 Mephenesin   59-47-2 Mephenesin is a centrally acting muscle relaxant which may work as an NMDA receptor antagonist.
CSN13916 MDL 105519 161230-88-2 MDL 105519 is a potent and selective inhibitor of 3Hglycine binding to the NMDA receptor with Kd of 389 nM
CSN25807 cis-α-(Carboxycyclopropyl)glycine 117857-95-1 L-CCG-IV is a potent agonist of the NMDA receptor.
CSN17128 L-701324 142326-59-8 L-701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor
CSN21303 Kynurenic acid sodium 2439-02-3 Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, 7 nicotinic acetylcholine receptor. Kynurenic acid is also a selective ligand of the GPR35 receptor.
CSN21125 Ibotenic acid 2552-55-8 Ibotenic acid has agonist activity at both the N-methyl-D-aspartate NMDA and trans-ACPD or metabolotropic quisqualate Qm receptor sites
CSN22199 GNE 5729 2026635-66-3 GNE 5729 is a brain permeable positive allosteric modulator of NMDAR with an EC50 of 37 nM for GluN2A 47 and 95 M for GluN2C and GluN2D respectively
CSN22417 GNE-0723 1883518-31-7 GNE 0723 is a brain permeable positive allosteric modulator of NMDAR with an EC50 of 21 nM for GluN2A 74 and 62 M for GluN2C and GluN2D respectively
CSN25810 Gavestinel sodium salt 153436-38-5 Gavestinel is a selective antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex with Kd of 0.8 nM.
CSN17519 Felbamate hydrate 1177501-39-1 Felbamate is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate NMDA
CSN21590 D-AP5 79055-68-8 D-AP5 is an antagonist of NMDA receptor (N-methyl-D-aspartate receptor).
CSN18296 CIQ 486427-17-2 CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit
CSN19842 CGP 37849 127910-31-0 CGP 37849 is a potent selective and competitive NMDA receptor antagonist Ki 35 nM
CSN22349 Apimostinel 1421866-48-9 Apimostinel is an oral NMDA receptor partial agonist.
CSN22086 7-Chlorokynurenic acid sodium salt 1263094-00-3 7-Chlorokynurenic acid sodium salt is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with Ki of 0.59 μM.
CSN25808 7-Chlorokynurenic acid 18000-24-3 7-Chlorokynurenic acid is an antagonist of NMDA receptor acting at the glycine site. It can also act as competitive inhibitor of L-glutamate transport into synaptic vesicles.
CSN24923 6-Methoxy-2-naphthoic acid 2471-70-7 6-Methoxy-2-naphthoic acid is an modulator of NMDAR.
CSN25440 1-Aminocyclobutanecarboxylic acid 22264-50-2 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1.
CSN23429 L-Glutamic acid   56-86-0 (S)-Glutamic acid acts as an excitatory neurotransmitter in the central nervous system.
CSN25118 D-Serine 312-84-5 (R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins.
CSN25441 (-)-Aspartic acid 1783-96-6 (-)-Aspartic acid is an endogenous NMDA receptor agonist.
CSN13883 Dizocilpine maleate 77086-22-7 ()-MK 801 Maleate is a highly potent, selective and non-competitive NMDA receptor antagonist with Ki of 30.5 nM.
CSN64512 Quinolinic acid 89-00-9
CSN50046 Bis(7)-tacrine dihydrochloride 224445-12-9
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